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50 Cards in this Set

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discriminatory zone of b-hCG with gestational sac in uterus
1500-2000

low = early pregnancy OR ectopic
high = ectopic
super high = molar

peaks at 10 wks at 100,000
What is Naegele's Rule to calculate EDD based off LMP?
(LMP - 3 months) + 7 days
*based on 28 d cycle
eg: LMP - June 8; EDD - March 15
Calculate EDD for LMP with 21 d cycle? 35 d cycle?
21 d --- subtract 0 d
35 d --- add 14 d
changes in heme
dilutional anemia
increased plasma volume x 50%
increased RBC x 30%
Coagulation factors increase
Fibrinogen increases (TE-lic)
changes in renal
GFR increases
lower BUN:Cr
dilation of collecting system secondary to progesterone
R>L since uterus lies to the R c/o sigmoid colon
changes in GI
constipation
GERD
nl LFTs
increased alk phos from placenta production
decreased total protein, albumin
changes in respiratory
respiratory alkalosis
increased TV
nl RR
decreased FRC
progesterone --> bronchodilates
changes in cardio
increased CO
increased plasma volume
decreased BP (2T, increased to baseline 3T)
decreased AFP
Down's syndrome
increased AFP
omphamacele
NTDs
multiples
what is the most common cause of abnormal AFP?
wrong dating
Anhydramnios, renal agenesis, flat facies, pulmonary hypoplasia
Potter Syndrome
sacral agenesis
aka caudal regression syndrome

c/o Classic DM anomaly (rare)
what are the risk factors of placenta previa?

how does it present?
RF = prior C-section/uterine surgery

presents = PAINLESS bleeding in 2T

dx = US; must be delivered by C/S
!placenta accreta --> hyst
what are the risk factors of placental abruption?

how does it present?
RF = HTN, smoking, cocaine, trauma

presents = PAINFUL with ctx +/- fetal distress; ! DIC

dx: clinical, US does NOT r/o; KLEIHAUER-BETKE
if stable, deliver vaginally
what is the pathogenesis of vasa previa?

how do does it present?
umbilical vessels run thru membranes and course over cervical os. vessels rupture during LND.

presents = after AROM, immediate rupture and severe decels or bradycardia

tx= STAT C/S. high mortality
dx: APT test
what is the number one cause of postpartum hemorrhage?

what are the risk factors?
uterine atony

RF= tired uterus, grand multip, multiple gestation, polyhydramnios, chorio, magnesium, pitocin, long labor, macrosomia
what is the treatment for uterine atony/pph?
1. pitocin and bimanual compression
2. methergine (!with HTN)
3. hemabate (!with asthma)
4. misprostol (!fever, GI distress)
5. Balkri balloon
6. Uterine emoblization
7. Surgery -- B-lynch, ligate uterine aa, hyst
what are the risk factors for retained products?

what is the treatment?
prematurity
placental abnormalities
manual extraction of placenta

tx = D&C
what are the risk factors for hereditary v. acquired coagulopathy?
Hereditary = factor deficiencies

Acquired/DIC = preeclampsia, eclampsia, HELLP, abruption, amniotic fluid embolism
what are the risk factors for preterm labor? What is the treatment?
RF = #1 prior preterm birth, multiple gestation, uterine anomalies, polyhydraminos, infection/chorio

tx = tocolytics (nifedipine, indocin, Mag)
Steroids. GBS proph.
what are the risk factors for PPROM?
what is the treatment?
RF = infection, labor, abruption, cord prolapse

tx = azithromycin. DO NOT TOCOLYZE to mask infection
Steroids. Hospitalization til 34 wks.
what are the risk factors for preeclampsia?
tx?
RF = extremes of age, nulliparity, new father, maternal disease (HTN, DM, collagen vascular disease, renal disease) multiple gestation

tx = 1. stabilize mother ... DELIVERY ** vaginal.
if laboring mother with dx of preeclampsia starts to seize, what should you do next?
1. ABCs
2. stabilize mother
NOT C/S
Describe the pathophysiology of gestational diabetes... what is the role of maternal glucose and insulin?
Glucose crosses the placenta. Insulin does not.
Fetal insulin acts like GROWTH FACTOR = MACROSOMIA
transient hypoglycemia postpartum
lemon/banana sign?
NTD
double bubble sign?
duodenal atresia, increased with Down's
omphalocele v. gastoschisis
omphalocele = other malformations; in sac

gastoschisis = random mutation; no membrane
what are the fetal causes for oligohydraminos?
maternal causes?
fetal = renal/bladder anomalies

maternal = compromised placenta, lupus, HTN
what are the fetal causes for polyhydraminos?
maternal causes?
fetal = GI tract obstruction (tracho-esophageal fistula, duogenal atresia, ileal atresia)

maternal = DM
Pt presents with hyperemesis, size greater than dates, vaginal bleeding, hypertensive and sweating

tx?
molar pregnancy

tx = suction D&C, follow beta for 6 m
!choriocarcinoma
Pt presents with chronic pelvic pain, dysmenorrheal, dyspareunia, cyclic pain...

tx?
endometriosis

exam: fixed retroverted uterus with uterosacral nodularity

tx:
1. NSAIDS
2. OCPs
3. Lupron
4. Surgical ablation
5. hyst
Multip woman presents with pain and heavy bleeding...
on PE, boggy, enlarged uterus...


tx?
Adenomyosis

tx: hyst
Pt presents with heavy bleeding, urgency and frequency...
PE = enlarged irregular uterus

tx?
Fibroids

tx:
1. no treatment
2. Lupron
3. ?children -- myomectomy
4. ?no more children -- hyst
***estrogen dependent
pt with significant vulvar pruritus, cigarette paper or parchment paper characteristic...

tx?
lichen sclerosis

tx: clobetasol
if pregnant with positive pap smear...
1. always colpo HGSIL
2. NO endocervical curettes
3. ASCUS and LGSIL deferred to postpartum
?ovarian cyst and premenopausal... how do we manage?
low oncology risk.
repeat US in 6 wks.
?CA125
what are the risk factors for urinary prolapse?

tx?
RF = childbirth, pregnancy, obesity, chronic cough, constipation

tx =
1. Kegels
2. Pessary
3. Surgery
tx for gonorrhea?
ceftriaxone
tx for chlamydia?
azithromycin x1 or doxy
tx for trich?
flagyl/metronadizole
dx and tx for syphillis?
PAINLESS ulcer
dx=
1. RPR/VRDRL --> FTA ABS

tx =
1. PCN
2. allergy -- Doxy or Erythro
Pregnant --- desensitize and tx with PCN
painful ulcer with inguinal lymphadenopathy

tx?
chancroid (H. ducreyi)

tx = azithro or ceftriaxone
painful, burning sores.
1st outbreak with prodrome

tx?
herpes

tx = valcyclovir, acyclovir
PID tx?

what about inpatient mgmt?
ceftriaxone, doxy +/- flagyl

inpatient (TOA, failed outpatient, can't tolerate po) =
cefoxitin/doxy
gent/clinda
Pregnancy infection with chicken pox.
how do we ID?
check IgG
+ = immune
- = varicella Ig
Herpes infection during pregnancy

how do we tx?
Valtrex at 36 wks.

inspect for lesions at labor -- ?C/S
Hep B prophylaxis during pregnancy
Baby gets Hep B and Hep B Ig
HIV positive pregnant woman

how do we manage?
mother - multidrug therapy; C/S (v. <1000 viral load)

intrapartum AZT

baby AZT for 6 mo; NO BREASTFEEDING
Pt presents with irregular periods, acanthos nigricans, facial hair, obese.

dx?

tx?
PCOS

dx: testosterone levels

tx: metformin +/- clomide (clomiphene)