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201 Cards in this Set

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Avodart generic
dutasteride
Avodart adverse effects
fetal damage (pregnancy X)
hirsutism
Claritin-D ingredients
loratadine
pseudoephedrine
Claritin-D dosing
1 tab q12h

extended release: 1 tab QD
Inspra generic
eplerenone
Uroxatral generic
alfuzosin
Uroxatral MOA
alpha 1 blocker
Uroxatral indication
functional symptoms of BPH
Hytrin generic
terazosin
Hytrin MOA
alpha 1 blocker
treprostinil brand
Remodulin
trepostinil MOA
direct dilator of both pulmonary and systemic arterial vascular beds
inhibits platelet aggregation
trepostinil indication
pulmonary arterial hypertension in pts w/ NYHA class II-IV symptoms
diazoxide brand
Hyperstat
diazoxide MOA
Vasodilator: direct smooth muscle relaxxation of peripheral arterioles which results in decrease in blood pressure and reflex increase in HR and CO

Hypoglycemia: inhibits insulin release from pancreas
diazoxide indications
hypertensive emergencies
hypoglycemia
nitroprusside brand
NitroPress
nitroprusside MOA
peripheral vasodilation by direct action on venous and arteriolar smooth muscle
increases CO by decreasing afterload
reduces aortal and left ventricular impedance
treatment of cyanide intoxication
amyl nitrite perles
sodium nitrite
sodium thiosulfate
Tolectin generic
Tolmetin
Tolectin MOA
NSAID
Tolectin should not be used in a patient with a
CrCL <25
Nitroglycerin sublingual tablets must be
packaged in a glass container
Senokot generic
senna
Senokot MOA
anthraquinone glycoside which produces mild stimulant effect on GI tract
Other stimulant laxatives
Cascara, Aloe
Advantages of stimulant laxatives
not significantly absorbed from GI tract which minimizes systemic side effects
Nor-QD generic
norethindrone
norethindrone pharmacologic category
progestin only oral contraceptive
Ortro-Gynol II jelly
non-oxynol-9
contraceptive
vaginal lubricant
What is an example of a phenytoin prodrug
fosphenytoin
fosphenytoin brand
Cerebyx
parenterally administered Dilantin
precipitation likely if combined w/ B-complex w/ C in an IV admixture (acidic)
IM administration should be avoided
morbilliform refers to
measleslike
drugs that are appropriate to use in status epilepticus
propofol
midazolam
lorazepam
Active ingredient in Colace
docusate sodium
docusate sodium MOA
anionic surfactant that promotes the penetration of water into the intestinal contents
Ingredient in Centrum is lycoopene. What is lycopene used for?
antioxidant that has been shown to reduce the incidence of prostate cancer
decreases LDL
Levodopa patients should avoid vitamin supplements that contain
pyridoxine (enhance peripheral conversion of levodopa to dopamine by dopa-decarboxylase)
Sinemet adverse effect
darkening of the urine
Cogentin generic
benztropine
switching from levodoopa to sinemet
permit at least 8 hours to elapse between last dose and first dose

daily levodopa dose in the Sinemet should be 75-80% lower that when levodopa is used alone
Product provides individual doses of carbidopa
Lodosyn
Emsam generic
selegiline
Emsam indications
orally for adjunctive therapy when Sinemet therapy is deteriorating

transdermally for major depressive disorder
Timoptic-XE generic
timolol (gel-forming solution)
timolol MOA
nonselective beta blocker that reduces IOP by reducing aqueous humor production or possibly outflow
Timoptic-XE dosing
instill 1 drop once daily

soln: instill 1 drop twice daily
acetazolamide brand
Diamox
acetazolamide MOA in glaucoma
carbonic anhydrase inhibitor decreases production of aqueous humor
dipivefrin brand
Propine
dipivefrin MOA
stimulates alpha/beta receptors increasing aqueous humor outflow
dipivefrin dosing
1 drop q12 hours
dipivefrin is a prodrug of
epinephrine
propofol brand
Diprivan
carbachol brand
Isopto
Miostat
Carbastat
carbachol MOA
cholinergic agonist increases aqeuous humor outflow
Normal IOP
10-20mmHg
Timoptic XE dosage form
gel forming solution
bimatoprost brand
Lumigan
bimatoprost adverse effects
conjunctival hyperemia
growth of eyelashes
ocular pruritus
Betagan generic
levobunolol
Betagan contains edetate disodium which functions as a
metal scavenger which binds free metal ions
Orudis-KT generic
ketoprofen
Advil ingredient
ibuprofen
Aleve ingredient
naproxen
Haltran ingredient
ibuprofen
Datril ingredient
acetaminophen
Actron ingredient
ketoprofen
Visine advanced allergy relief generic
tetrahydrozoline
Visine advanced allergy MOA
alpha 1 agonist
Timoptic XE and levobunolol adverse effect
respiratory distress
Benzac AC wash generic
benzoyl peroxide
BenzaClin generic
clinamycin and benzoyl peroxide
Retin-A warnings
avoid excessive sunlight exposure
avoid contact w/ eyes, mucous membranes, etc
do not use 0.05% crm longer than 48wks
do not use 0.02% crm longer than 52wks
gel is flammable
tretinoin MOA
keratinocytes in sebaceous follicle become less adherent

inhibits microcomedone formation and eliminates lesions already present
retin-A liquid containes buylated hydroxytoluene which its function is
oil-soluble antioxidant
Retin-A micro is a product that is only available as a
gel that containes microspheres
Accutane is most closely related to
beta carotene. It contains isotretinoin that is an isomer of retinoic acid, a metabolite of retinol (vitamin A). betacarotene is provitamin A
Common adverse effects of Accutane
chelitis
conjunctivitis
hyperlipidemia
Accutane administration oral
administer with food
capsules can be swallowed or chewed and swallowed
capsule can be opened and contents placed on applesauce or ice cream
whole caps should be swallowed with a full glass of liquid
Accutane prescriptions
written for a 1-month supply and must be filled within 7 days
Bravisol containes aluminum oxide which is an ingredient used
as an abrasive. aluminum oxide is a water-insoluble material
Pernox scrub contains salicylic acid which is used
as a keratolytic agent
Vanceril generic
beclomethasone (Beconase AQ, QVAR)
Using Proventil Aerosol in an elderly patient may require the use of a
spacer device
What formulations is Proventil available in?
aerosol
powder for inhalation
oral liquid
oral tabs
What should be done when Proventil Aerosol and vanceril Aerosol are to be used at the same time?
use the broncodilator at least several minutes before the corticosteroid to promote better passage of corticosteroid into the lower lung
Habitrol generic
Nicotine
Nicotine brandnames
Commit
NicoDerm CQ
Nicorette
Nicotrol inahler
Nicotrol NS
Nicotrol Patch
How to determine what strength gum a smoker should begin with
<25cigarettes/d = 2mg
>25 cigarettes/d = 4mg
Nicotine gum dosage breakdown
weeks 1-6: chew 1 piece of gum q1-2h
chew at least 9 pieces/d during first 6 weeks

weeks7-9: chew 1 piece of gum q2-4hours

weeks10-12: chew 1 piece of gum q4-8hours
Nicotine inhaler use
6-16 cartidges per day (freq cont puffing q20minutes)

duration 3 months

wean from inhaler by reduction in daily dose over 6-12wks
How to determine the nicotine lozenge strength
patients who smoke first cigarette w/in 30mins of waking = 4mg

otherwise 2mg strength recommended
Nicotine lozenge dosing breakdown
weeks 1-6: one lozenge q1-2h

weeks 7-9: one lozenge q2-4h

weeks 10-12: one lozenge q4-8h

use atleast 9 lozenges per day (max 20/d)
Nicotine spray dosing
1-2sprays/hr (max 10sprays/hr; 80sprays/d)
2sprays contains how much nicotine
1mg
Nicotine trasdermal patch directions
apply new patch q24h to nonhairy, clean,d ry skin on upper body or upper outer arm
NicoDerm CQ directions
>10cigs/d: begin w/ step 1 (21mg/d) x4-6wks, followed by step (14mg/d) x2wks; finish w/ step 3 (7mg/d) x2wks

<10cigs/d: begin step 2 (14mg/d)x6wks, followed by step 3 (7mg/d)x 2wks
NicoDerm CQ initial starting dose in patients <100 poiunds or hx of cardiovascular disease
14mg/d x4-6wks, followed by 7mg/d x2-4wks
Nicotrol directions
one patch daily x6wks
Benefits of use of nicotine trasdermal patches beyound ___ months have not been demonstrated
3
Nicotine gum counseling
chew slowly until it tingles, then park gum between cheek and gum until tingle is gone; repeat process until most of tingle is gone (30mins)
Nicotine patch interesting fact
contains metal (aluminum) remove in MRI
Advantage of albuterol over isoproterenol is
fewer cardiac effects
isoproterenol brand
Isuprel
isoproterenol MOA
beta1/2 agonist resulting in relaxation of bronchial, GI, and uterine smooth muscle, increased HR and contractility, vasodilation of peripheral vasculature
Atrovent generic
Ipratropium
Tornalate generic
bitolterol (bronchodilator)
Maxair generic
pirbuterol (beta2 agonist)
Beclovent generic
beclomethasone
Sustaire generic
theophylline
theophylline MOA
blocks phosphodiesterase
dipyridamole MOA
inhibits activity of adenosine deaminase and phosphodiesterase

inhibits platelet aggregation and may cause vasodilation
dipyridamole brand
Persantine
Humalog generic
insulin lispro
Humalog notes
recombinant DNA tech
clear solution
How many mL's if a patient needs 32 U lantus dose?
0.32mL
100units/mL
Units for blood glucose
mg/dl
Symlin generic
pramlintide
Symlin MOA
amylinomimetic
reduces PPG increases via:
1)prolongation of gastric emptying
2)reduction of postprandial glucagon secretion
3)centrally mediated appetite suppression

type 1 and 2
Symlin storage
unopened vials: refrigerated
opened vials: refrigerated or room temp

discard opened vial after 28 days
Insulin that does not have a pH of 7.4?
Lantus

not compatible with other insulins
B-D lo-Dose syringes capacity
0.5mL (useful if measuring <50units)

others are 1.0mL
Diabeta generic
glyburide
Prandin generic
repaglinide
Precose generic
acarbose
2nd generation sulfonylureas
glyburide (Diabeta, Micronase)
glimepiride (Amaryl)
glipizide (Glucotrol)
Thyrolar generic
liotrix
liotrix composition
T4:T3 in 4:1 ratio by weight
Cytomel generic
liothyronine
liothyronine composition
T3
Euthroid generic
liotrix
Use of thyrolar and effect on warfarin requirement
increases the catabolism of vitamin K dependent clotting factors which decreases warfarin requirment
administred in a radiation emergency
potassium iodide
NSAIDs effect on warfarin
displaces warfarin from protein binding sites increasing its effect
Empirin/Codeine and warfarin interaction
Aspirin can displace warfarin from protein binding sites increasing its effect
Trimox generic
amoxicillin
Bactrim generic
trimethoprim/sulfamethoxazole
Septra generic
trimethoprim/sulfamethoxazole
Bactrim MOA
sulfa: inhibition of dihydrofolic acid formation from para-aminobenzoic acid (PABA)

trimethoprim: inhibits dihydrofolic acid reduction to tetrahydrofolate resulting in sequential inhibition of enzmes of folic acid pathway
Bactrim administration
8oz of water on an empty stomach, 1 hr before or 2 hours after meals for best absorption
Avelox generic
moxifloxacin
Levaquin generic
levofloxacin
meperidine and MAO-I interaction
may enhance the serotenergic effect of meperidine
can test urine with this to determine the presence of bacteruria
microstix-3

designed to test for nitrite in urine
Pyridium generic
phenazopyridine
Pyridium classification
urinary analgesic
Pyridium should not be administered for longer than
2 days
Tests for urine ketones
Acetest
Ketostix
Uristat generic
phenazopyridine
Symptoms of PMS
backache
cramping
edema
irritability
weight gain
Midol PMS formula
APAP
Pamabrom
Pyrilamine
Other brand names for Midol
Pamprin multisymptom
Premsyn PMS caplets
Microbes responsible for conjunctivitis
staph aureus
staph epidermidis
strep pneumoniae
opthmalic quinolones for conjunctivitis
ciprofloxacin (Ciloxan)
ofloxacin (Ocuflox)
Ancoban generic
flucytosine
Risk factors for macular degeneration
aging
HTN
females > males ?
sunlight
smoking
Dietary supplements that have shown some effectiveness in reducing age-related macular degeneration (AMD)
lutein
vitamin C
vitamin E
zinc + copper
Methods of reducing the incidence of AMD
smoking cessation
reduction of HTN
sunglasses
daily antioxidants
Factors that contribute to why females are more prone to incontinence than males
less well-defined internal sphincter
greater depednence on body estrogens (decline in estrogen in post-menopausal women increases risk)
Urinary catheter for men
Texas (external catheter attached around penis to allow urine flow)
Urinary catheters for anyome
Foley
intermittent catheters

(both inserted through the urethra into the bladder)
Given for bladder irrigation for disinfecting the urinary tract and catheter
diluted acetic acid 0.25%
Vitamin B12 injection storage color
clear pink to red solutions are stable at room temperature
Vitamin B12 dosage forms
injection solution
intranasal solution spray
lozenge
tablet (oral , SL)
Resin (oral, SL, buccal)
Which of the following drugs may contribute to iron deficiency anemia?

a)aspirin
b)ampicillin
c)multivitamins
d)tetracycline
e)vitamin B complex
aspirin-GI bleed
Criteria for diagnosis of type 2 diabetes
1)symtoms of diabetes plus random plasma glucose >= 200mg/dL

OR

2)fasting plasma glucose >= 126mg/dL on 2 occasions

OR

3)2 hour plasma glucose >= 200mg/dL during OGTT with 75 gram glucose load
How long before noticeable improvement after taking Zoloft?
2-4weeks
Compression stockings notes
-stockings should be put on first thing in the morning

-stockings designated as antiembolism stockings exert only 20mm of pressure

-stockings with gradient pressures exert the greatest pressure on the lower extremities
Nasonex generic
mometasone
Nasonex notes
-prior to first use prime pump by actuating 10 times

-use in each nostril daily
mometasone brand
Asmanex, Twisthaler, Elocon, Nasonex
Clarinex generic
desloratadine
Clarinex dosage forms
tablets
reditabs
Clarinex dosing
5-10mg QD
Clarinex versus Allegra potency
Clarinex more potent

5-10mg QD vs. 60mg BID - 180mg QD
Aleve generic
naproxen
Alavert generic
loratadine
Contac generic
pseudoephedrine
Tavist generic
clemastine
Vivarin generic
caffeine
What is the active ingredient in Burow's solution?

What is this ingredient used as?
5% aluminum acetate used as an astrigent dressing
Burow's solution uses?
athlete's foot
diaper rash
dry skin
dermatitis such as poison ivy
Use of Aquaphor
good absorbent of liquids such as Burow's solution and will ease its incorporation into the oleaginous petrolatum base.
Another name for carbolic acid
phenol
Use of salicylic acid in topical products
keratolytic agent
Digoxin drug interactions: increased effect
amiodarone (reduce digoxin dose 50%)
cyclosporine
itraconazole
erythromycin/clarithromycin
methimazole
quinidine (reduce digoxin dose 33-50% on initiation)
methylphenidate brand names
Concerta, Daytrana, Metadate, Methylin, Ritalin
Daytrana administration
10mg patch once daily, remove up to 9 hours after application; application should occur 2 hours prior to desired effect to hip area alternating daily
Concerta administration
with or without food but should be taken with water, milk, or juice

other tablets and SR products should be taken 30-45 minutes before meals
Orap generic
pimozide
Cylert generic
pemoline
Strattera generic
atomoxetine
pimozide MOA
atypical antiphyschotic agent that is a potent centrally acting dopamine receptor antagonist
pemoline
CNS stimulant
pemoline adverse effect
severe hepatic failure (withdrawn from market)
atomoxetine MOA
selectively inhibits the reuptake of NE
atomoxetine adverse effects
headache, insomnia
xerostomia
decreased appetite
nausea, vomiting, abdominal pain
pimozide indications
suppresion of severe motor and phonic tics in pts w/ Tourette's syndrome
atomoxetine indications
ADHD