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22 Cards in this Set

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What is another name for Vitamin B3?
Niacin
In the body, what are 3 functions of Niacin?
Crutial to ATP production
Co-enzyme in energy metabolism
RBC formation
What are some sources of Vit B3?
Lean meat, poultry, fish
Peanuts & peanutbutter
Fortified breads & cereals

**Indirectly from the conversion of tryptophan by intestional microbs.**
Excess niacin results in…(3 items)
Facial Flushing
Decrease in blood lipids (it’s a good thing)
Can damage the liver
What is the name for a deficiency in Niacin/B3?
Pellagra
Pellagra is also known as goose flesh.
What are the 3 classic symptoms for Pellagra?
1) Dementia 2) Diarrhea 3) Dermatitis
(4-- Eventual Death)
What are some mucus membrane symptoms of Pellagra?
Scarlet glossitis
Ulcerations may appear underneath the tongue, mucosa of lower lip & buccal mucosa
Gingival inflamation may resemble ulcerative gingivitis

**Remember Pellagra can be associate with a heavy Maze diet-->usually outside of the US.**
What is another name for Vitamin B6?
Pyridoxine
*Need to know this term*
What are the 3 primary functions of Pyridoxine (Vit B6)?
1)Co-enzyme
2) Converts tryptophan to Niacin
3) Hemoglobin synthesis for RBC's
What foods provide Vit B6?
Meat, poultry, fish, & Eggs
Whole Grains
Non Citrus Fruits
Legumes
Dark green leafy vegetables
What does and Excess of Pyridoxine lead to? Deficiency?
Excess: Toxicity tymptoms from Megadoses like:
Ataxia (loss of coordination)
Bone & muscle weakness
Severe sensory neuropathy
Deficiency: Glossitis & Angular Chelitis (cheilosis)

**It is the most toxic of the B vitamins…think deficiency with red or burning tongue.**
What is another name for Folate?
Folic Acid
Folate is a co-enzyme for approximately ___ other enzymes.
20 other enzymes
As far a reproduction goes what is so important about Folic Acid?
What about its importance with RBC's?
Synthesis of DNA & RNA.
Involved in the maturation of RBC's

**Also its important in the proper formation of neural tubes during fetal development.*
What is a major source of Folic Acid?
Dark Green Leafy Vegetables-->Spinach!
What are the most common deficiences among the B Vitamins? (4 items)
Neural Tube Defects
Cleft lip/palate
Megaloblastic anemia (blood disorder w/ apperance of very large RBC's)
Glossitis (Firey red denuded papillae)

*Alcoholics are at risk for Vit B deficiency too.**
What is another name for Vit B12?
Cobalamin
What are the physiological roles of Cobalamin?
Converts folate into a form that is used to produce RBC's & nucleic acids for DNA snythesis
Formation & regeneration RBC's and for myelin synthesis

**10-30% of elderly may be unable to absorb B12 naturally due to reduced stomach acidity/lack of intrinsic factor-->Get B12 shots.**
What are typical sources for B12/Cobalamin?
Animal Protein
Organ Meat
Milk/Cheese/Eggs
Fish
In addition to the elderly who else might be at risk for a B12 deficiency?
Vegans-->since no intake of animal foods.
A deficency in Vit B12 is also called Cobalamin deficency.
What are some conditions of this deficency? (3)
Pernicious Anemia (immature RBC's)
Stomatitis or yellowish mucosa
Hemoragic gingiva & bone loss.

*Possible link to Alzheimer's risk.*
What is Biotin & Pantothenic acid good for?
They are coenzymes for the metabolism of :
Carbs, Fats & Proteins