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16 Cards in this Set

  • Front
  • Back

Vitamin A

Function
Deficiency
Excess
Source
Retinol

* Function *
Constituents of visual pigments

* Deficiency *
Night blindness
Dry Skin

* Excess *
Arthralgia
Fatigue
H/a
Sore throat
Alopecia

* Source *
Green Leafys
Vitamin B1

Thiamine

* Function *
Oxidative decarboxylation of alpha keptoacids
Transketolase (HMP shunt)

* Deficiency *
Dry Beriberi: polyneuritis, muscle wasting
Wet Beriberi: high output failure, edema
Wernicke-Korsakoff: CNS Hemorrhagic lesions, confusion, ataxia, ophthalmoplegia, memory loss, confabulation
Vitamin B2
Riboflavin

* Function *
FADH2 (Redox)

* Deficiency *
Angular stomatitis
Cheilosis
Corneal vasculature
Vitamin B3
Niacin

* Function *
NAD/NADP

* Deficiency *
Pellagra: Diarrhea, Dermatitis, Dementia,

Causes:
Hartnup Dz (reduced trp abs)
Malignant Carcinoid (trp metabolism
INH (less B6)
Vitamin B5
Pantothenate

* Function *
Component of CoA
Fatty acid synthase

* Deficiency *
Dermatitis
Enteritis
Alopecia
Adrenal Insufficiency
Vitamin B6
Pyridoxine

* Function *
Transamination
Decarboxylation
Heme Synthesis

* Deficiency *
Convulsions
Hyperirritability (inducible by INH and OCP)
Peripheral neuropathy
Vitamin B12

Cobalamine

* Function *
Homocysteine methylation
Methylmalonyl CoA handling

* Deficiency *
Megaloblastic anemia
Optic neuropathy
Paresthesias
Glossitis

* Causes *
Sprue
Enteritis
Diphyllobothrium latum
Pernicious anemia
Crohn's Dz

* Diagnostics *
Schilling Test
Folic Acid
* Deficiency *
Megaloblastic anemia without neuro
Neural tube defects in fetus

* Function *
THF required for methylation
Base synthesis
Biotin
* Deficiency *
Dermatitis
Enteritis

* Carboxylation:
Pyruvate --> oxaloacetate
Acetyl CoA --> Malonyl CoA
Proprionyl-CoA --> methylmalonyl CoA
Vitamin C
* Deficiency *
Scurvy:
swollen gums
bruising
anemia
poor wound healing

* Function *
proline and lysine hydroxylation
DA --> NE synthesis
Vitamin D
* Deficiency *
Osteomalacia (children)
Osteoporosis (adults)
hypocalcemic tetany

* Function *
GI Ca uptake
Vitamin E

* Deficiency *
Hemolysis
Neurodysfunction

* Function *
Antioxidant
Vitamin K

* Deficiency *
Bleeding

* Function *
Carboxylation of II, VII, IX, X, Protein C, Protein S
Zinc
* Deficiency *
Delayed wound healing
hypogonadism
reduced hair
Kwashiorkor

Protein deficit

Skin lesions
edema
Hepatic fatty change
Marasmus
Total calorie deficiency

muscle wasting
loss of sc fat
edema