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21 Cards in this Set

  • Front
  • Back
vitamine
coined by Casimir Funk upon isolation of thiamin-containing accessory factor

termed "vital amine" because of the presence of an amine group
vitamin (5 criteria)
1. organic compound
2. natural component of food
3. essential in minute amounts for normal physiological function
4. deficiency results in specialized syndrome
5. not synthesized in adequate amounts by host
vitamers
isomers of the same vitamin "family"
provitamin
precursor of an actual vitamin

ex: carotenoids metabolized to form active vitamin A
scurvy
disease related to vitamin C deficiency

involves sore gums, painful joints, and multiple hemorrhages
beriberi
disease related to thiamin deficiency

involves severe fatigue, complications of cardiovascular, nervous, GI, and muscular systems
rickets
disease of growing bones (vitamin D deficiency)

involves deformation of long bones, swollen joints, and/or enlarged heads
pellagra
disease related to niacin deficiency

involves lesions of skin and mouth and GI and mental disturbances
requirements of nutrition research
1. repeatability
2. relevance
purified diet
diet of defined composition

formulated using highly refined ingredients with well known chemical compositions

provided predictability (through being repeatable)
polyneuritis
damaged nerves of peripheral system

symptom of thiamin deficiency in chickens
accessory factor
factors (aside from fats, proteins, and carbohydrates) that are required in small amounts for growth
vitamine theory
presented by Funk

discarded germ theory and provided new concept for interpretation of diet-related phenomena
xerophthalmia
xeros = "dry"
opthalmos = "eye"

dryness of eyeball, hyperkeratosis of conjunctiva, and inflammation/edema of cornea

leads to infection, ulceration, and blindness

symptom of vitamin A deficiency
beta-carotene
provitamin for vitamin A
retinen
chromophore (retinal pigment) formed by oxidation of vitamin A

aka RETINAL
ergocalciferol
vitamer of Vitamin D

formed from ergosterol

called vitamin D2
cholecalciferol
vitamer of vitamin D

formed from cholesterol

called vitamin D3
flavin
initially, used as describer of accessory factors with a prefix indicating the source material in which it was isolated from:

ovoflavin (egg white)
hepatoflavin (liver)
lactoflavin (milk)

later called riboflavin
black tongue disease
necrotic degeneration of the tongue

clinical manifestation of niacin deficiency in animal models

led to discovery of niacin
bioavailability
proportion of an ingested nutrient that is absorbed/retained/metabolized through pathways to exert normal physiological function