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32 Cards in this Set

  • Front
  • Back

What effect does a pure agonist cause?

A 100% positive reaction

What are the side effects of salbutamol?

Bronchodilation


Tachycardia


Agitation


What is the best drug to prevent/reduce the imflammatory response in asthma??

Prednisolone- Steroid

What is the best anticholingergenic drug used to treat COPD

Ipratropium - affects parasympathetic system

What is the best drug to treat candiadiasis (thrush)

Nyastatin

Why do they use levodopa instead of dopamine for parkinsons?

Dopamine does not cross the blood brain barrier.

What is the half life of levodopa?

Half an hour.

What are donepezil, galentamine and rivastigmine used to treat?

Alzheimers

Why is memantine only used rarely in alzheimers?

Because it destroys nerve cells

What are the side effects of the alzheimers drugs galantamine and rivastigmine?

Affects the parasympathetic nervous system- bradycardia, reduced blood pressure, weight loss, cardiac issues

What drug is often given to people with nerve pain?

Amitriptyline at night- antidepressant

What happens if you stop anti-depressants suddenly?

Your body has become used to not having to produce as many neurons because the anti-depressants are making artifical ones which leaves a massive imbalance

What do interneurons do?

Transmit impulses between neurone in the brain

What does serotonin effect?

Controls the sleep wake cycle, temperature, pain perception, aggression and nausea and vomiting

Where is acetylcholine found?

Found in skeletal pathways


Linked to degnerative diseases


What does noradrenaline control?

Sense of arousal, altertness and mood

What does dopamine control?

Mood, motivation and sexual behaviour

What happens if someone has too much dopamine?

Psychosis can form- distrupts PNS

Where is Gamma aminobutyric acid found?

Central nervous system


What type of drugs are benzopiazines?

Anti-anxiety drugs

How to benzodiazepines work?

By depressing part of the brain that regulates activity levels- increasing the action of a substance called gamma-aminobutyric acid (GABA)

What does anaesthesia provide?

Analgesia


Amnesia


Immobilisation


What are the routes of anaesthesia?

Inhalation


Intravenous


Local

When are inhalation anaesthetic used?

Labour


bone Injury



As well as anaesthetic what else is used in surgery?

Neuromuscular blocking agents

What is the difference between non- depolarising and depolarising neuromuscular blocking agents?

You have to wait for depolarising agents to wear off.


Neuromuscular blocking agents non depolarising?

Atracurium


Vecuronium


Pancuronium


Tubocurarine

Depolarising neuromuscular blocking agents?

Suxemethonium- mostly used in intensive care for brain injury


What is propofol? Think MJ

Induction agent used to get patients to sleep

What is fentanyl?

A pain medicine used beore during and after surgery

What is succinylcholine?

A muscle relaxant that makes placement of breathing tubes and surgery easier to achieve

What is halothane?

An anesthesia gase used to keep patients asleep for surgery delivered though a breathing tube or mask