Nursing 3Rd Medsurg: Respiratory Drugs

Front 1

Isoniazid or ____ is a medication used to treat ________.

Back 1

Isoniazid or INH is a medication used to treat tuberculosis.

Front 2

Isoniazid or INH is an antitubercular. Other than treating TB, it can also be used for what? Is it first line or second line? What is the most common side effect?

Back 2

Isoniazid or INH is a first line therapy of active tuberculosis, in combination with other agents. It is also used alone in prevention of TB in patients exposed to active disease or in tx of latent TB.
The main neuro symptom is peripheral neuropathy. It can also cause a rash, and other CNS side effects such as psychosis, seizures, and visual disturbances.

Front 3

Isoniazid or INH can cause drug induced _______. Patients should regularly have _____ function evaluated prior to and monthly throughout therapy. Caution patients to avoid the use of _____ during therapy, as this may increase the risk of ______.

Back 3

Isoniazid or INH can cause drug induced hepatitis. Patients should regularly have liver function evaluated prior to and monthly throughout therapy. Caution patients to avoid the use of alcohol during therapy, as this may increase the risk of hepatotoxicity.

Front 4

Pyridoxine may be used concurrently with INH or Isoniazid to prevent ______.

Back 4

Pyridoxine may be used concurrently with INH or Isoniazid to prevent neuropathy.

Front 5

Rifampin or Rifadin is used to treat what? It's a __________ in the ____ pharmacologic class.

Back 5

tuberculosis. It is an antitubercuin in the rifamycin pharmacologic class.

Front 6

What are the main side effects of Rifampin?

Back 6

Red discoloration of body fluids
GI symptoms (abdominal pain, diarrhea, flatulence, heartburn, nausea, vomiting)
thrombocytopenia

Front 7

What are 3 nursing implications involved with the administration of Rifampin?

Back 7

RIfAMpin
Report flu like symptoms
Interferes with birth control
Avoid alcohol during use.
Monitor liver & renal function as well as uric acid levels

Front 8

Ethambutol is used to treat active TB or other mycobacterial diseases (with at least one other drug). How does it work?

Back 8

Ethambutol is used to treat active TB or other mycobacterial diseases (with at least one other drug). It inhibits growth of mycobacteria, a tuberculostatic or bacteriostatic effect.

Front 9

Safety is not established for the use of Ethambutol in children younger than ___. What are the main side effect?

Back 9

13
OPTIC NEURITIS
Also can cause GI s/s
(hepatitis, abdominal pain, anorexia, nausea, vomiting)
neuro s/s (peripheral nephritis confusion, h/a, malaise, dizziness, hallucinations)

Front 10

What needs to be monitored with Ethambutol?
5

Back 10

Regular assessments of visual function. Advise patient to report blurred vision, constriction of visual fields, or changes in color perception immediately. Visual impairment, if not identified early, may lead to permanent slight impairment.

Monitor renal, hepatic function, CBC, and uric acid levels. Frequently causes elevated uric acid concentrations, which may precipitate an attack of gout.

Front 11

Which TB drug should not be given to pregnant women?

Back 11

Pyrazinamide (PZA)

Front 12

Pyrazinamide (PZA) is used in combination with other agents in the tx of active TB. Is it first line or second line? Is the action bactericidal or bacteriostatic?

Back 12

First line
Bacteriostatic

Front 13

Pyrazinamide (PZA) can cause life threatening hepatotoxicity when taken with _____ and should be avoided.

Back 13

Rifampin

Front 14

Many TB drugs can have ____ ______. For example, if someone is allergic to ethionamide, isoniazin, they may also be allergic to Pyrazinamide (PZA).

Back 14

cross sensitivity

Front 15

The main side effects of Pyrazinamide (PZA) include ______.
what are 2 others?

Back 15

hyperuricemia
Other side effects include photosensitivity & arthralgia

Front 16

What's is pyroxidine commonly known as? It can be used with ____ to prevent ______.

Back 16

Pyroxidine is Vitamin B 6 and can be used with INH to prevent neuropathy.

Front 17

What should be monitored with Pyrazinamide (PZA)? When may this drug be contraindicated?

Back 17

Monitor serum uric acid concentrations.
Evaluate hepatic function regularly (q 2-4 weeks) during therapy. Increased liver function tests may not be predictive of clinical hepatitis and may return to normal levels during tx.
Contraindicated in pregnancy. Patients with impaired liver function should receive this drug only if crucial to tx.

Front 18

Diabetic patients taking (Pyrazinamide) PZA should know that it can interfere with ____ _____ determinations.

Back 18

Diabetic patients taking (Pyrazinamide) PZA should know that it can interfere with urine ketone determinations.

Front 19

rifabutin (Mycobutin) is an agent that is effective against atypical mycobacterium. It is a ____ line drug. It is commonly used in npatients with advanced ___.

Back 19

first
HIV

Front 20

The main side effect of rifabutin (Mycobutin) is...

Back 20

brown-orange discoloration of urine

Front 21

What are the nursing Implications about rifibutin (Mycobutin)?

Back 21

Monitor bowel function. Diarrhea, abdominal cramping, fever, and bloody stools should be reported because they are a sign of pseudomembranous colitis

May interfere with birth control

Monitor CBC, may cause neutropenia, thrombocytopenia

.

Front 22

When is rifabutin (Mycobutin) contraindicated?

Back 22

Pregnancy (safety not established)
Active TB

...? (deglin p 1111)

Front 23

Don't take ________ with rifabutin (Mycobutin) if GI side effects occur.

Back 23

antidiarrheals
(could be pseudomembranous colitis, need to get tx)

Front 24

rifapentine or Priftin is an antitubercular used to treat pulmonary TB. It is contraindicated in hypersensitivity to _____ or _____. Use extreme caution with protease ____ therapy.

Back 24

rifapentine or Priftin is an antitubercular used to treat pulmonary TB. It is contraindicated in hypersensitivity to rifamycins- rifampin or rifabutin. Use extreme caution with protease inhibitor therapy.

Front 25

rifapentine or Priftin may interfere with ____ _____. It must be used in conjunction with other antituberculars. What is a main complication?

Back 25

birth control
Pseudomembranous colitis

Front 26

___________ is an aminoglyocide also commonly used as a first line drug in tx of TB. What are the common side effects?

Back 26

Streptomycin
liver toxivity,
renal toxcity, ototoxicity