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32 Cards in this Set
- Front
- Back
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Example of a meglitinide?
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Repaglinide
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Example of a biguanide?
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Metformin
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Example of a sulfonlurea?
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Glipizide
Glyburide |
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Example of a Alpha glucosidase inhibitor?
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Acarbose
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Example of a glitazone?
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Rosiglitazone
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Other name for sitagliptin?
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Januvia
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Other name for Metformin?
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Glucophage
Janument Metfromin/Sitagliptin |
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Other name for repaglinide?
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Prandin
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MOA of repaglinide?
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Stimulates release of pancreatic insulin
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MOA of metformin?
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Decreases hepatic glucose production increase peripheral insulin sevsitivity
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MOA of glipizide?
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increases pancreatic insulin release
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MOA of acarbose?
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Delays breakdown or absorption of carb in gut
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MOA of rosiglitazone?
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Promotes muscle and fat glucose uptake
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SE of Repaglinide?
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short acting
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SE of Metformin?
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Lactic acidosis
diarrhea nausea |
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Contra to taking Metformin?
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CR>1.4
liver dx Etoh abuse CHF acute illness |
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How do you monitor Metformin?
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Periodic Cr & CBC
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If a meal is skipped, what when should Repaglinide be taken?
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don't take if skipping meal
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How should Repaglinide be adjusted?
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titrate to meals
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Glipzide SE?
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hypoglycemia
90% liver excr. t1/2 12-24 hr |
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Glipzide contra?
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liver dx
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Glipzide monitoring?
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BG daily when increasing dose
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Glyburide SE?
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hypoglycemia;
mostly renal excr t 1/2 24 hr |
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Glyburide contra?
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renal dx
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Glyburide monitoring?
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BG daily when increasing dose
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Acarbose MOA?
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delays breakdown absorption of carbs in gut
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Acarbose SE?
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flatulence
abdominal pain dose dependent liver toxicity |
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Acarbose contra?
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GI disorders
liver dx |
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Rosiglitazone MOA?
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promotes muscle and fat glucose uptake
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Rosiglitazone SE?
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Liver toxicity fluid retention
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Rosiglitazone contr?
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ALT > 1.5 x nl
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Monitoring for Rosiglitazone?
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ALT q month for six months then periodic
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