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35 Cards in this Set

  • Front
  • Back
importance of nuleic acids
they store and process information at the molecular level. DNA-genetic blueprint
RNA- carries out instructions of DNA.
RNA is located
mostly in the cytoplasm
DNA is located
in the nucleus
3 components of nucleotides
1. nitrogenous base
2. pentose sugar
3. phosphate group
DNA's pentose sugar
deoxyribose
RNA's pentose sugar
ribose
nucleic acids contain
carbon, oxygen, hydrogen, nitrogen, and phosphorus
purines
adenine (A) and guanine (G)
pyrimidines
uracil (U), cytosine (C), and thymine (T)
nitrogen bases of RNA
adenine, uracil, cytosine, and guanine
nitrogen bases of DNA
adenine, thymine, cytosine, and guanine
dsDNA is held together with
H bonds between the bases
DNA
long double stranded polymer
contains instructions for gene expression/protein synthesis
RNA
single strands of nucleotides
does the grunt work of protein synthesis
the genetic code
method of information instruction and storage in DNA
triplet
sequence of 3 nitrogen bases that signal for a specific amino acid.
gene
functional unit of heredity. a gene contains a triplet code to encode for a protein.
promotor
start segment of a gene. needs to be unbound from a histone for the gene to be activated.
DNA replication
occurs in the nucleus. a copy of each parent gene must go into each daughter cell. requires DNA, helicases, nuleotides, and DNA polymerase.
helicases
unwind the dsDNA and break the H bond between the DNA strands. the exposed nitrogen bases are complimentary base paired to create a new strand of DNA. this is done by DNA polymerase.
DNA polymerase
enzyme needed to synthesize new DNA. copies the DNA by complementary base pairing. also acts as a "spell checker" to correct any nucleotide misplacement.
mutations
occur when nucleotide misplacement is not corrected. point mutations (one nucleotide wrong in a triplet) can cause diseases such as sickle cell anemia.
gene activation
once the histone moves away from the gene's promoter and the h bonds are broken between the complementary bases, the gene is activated.
RNA polymerase
binds to the promoter of a gene and starts synthesizing mRNA from DNA template strand by complementary base paring (A-U, T-A, C-G. G-C)
coding strand
contains the actual gene squence for the protein being made. complementary base paired with the template strand.
template strand
acts as a template for the RNA polymerases to make mRNA.
transcription
process which mRNA is transcribed from DNA template strand. RNA polymerase takes notes or transcribes the mRNA. done inside the nucleus. needs DNA, RNA polymerase, and nucleotides to make mRNA
codon
triplet code of nitrogen bases for mRNA to encode for a specific protein.
immature mRNA
includes codons for functional protein plus nunsense codons. nonsense codons must be edited out before the mRNA leaves the nucleus.
introns
nonsense regions of a gene or immature mRNA
exons
coding regions for functional proteins spliced together for mature mRNA
splicing
process of cutting out introns and ligating exons by nuclear enzymes
translation
translating the message from mRNA into an actual protein. occurs at the ribosomes in the cytoplasm. requires mRNA, tRNA, and rRNA to make the protein.
transfer RNA (tRNA)
brings the specific amino acid to the ribosome for protein synthesis.
anticodon
code on the tRNA to complement mRNA codon. the correct amino acid is carried by the tRNA that has a complementary base pairing of its anticodon with the mRNA's codon.