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35 Cards in this Set
- Front
- Back
importance of nuleic acids
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they store and process information at the molecular level. DNA-genetic blueprint
RNA- carries out instructions of DNA. |
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RNA is located
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mostly in the cytoplasm
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DNA is located
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in the nucleus
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3 components of nucleotides
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1. nitrogenous base
2. pentose sugar 3. phosphate group |
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DNA's pentose sugar
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deoxyribose
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RNA's pentose sugar
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ribose
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nucleic acids contain
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carbon, oxygen, hydrogen, nitrogen, and phosphorus
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purines
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adenine (A) and guanine (G)
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pyrimidines
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uracil (U), cytosine (C), and thymine (T)
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nitrogen bases of RNA
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adenine, uracil, cytosine, and guanine
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nitrogen bases of DNA
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adenine, thymine, cytosine, and guanine
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dsDNA is held together with
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H bonds between the bases
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DNA
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long double stranded polymer
contains instructions for gene expression/protein synthesis |
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RNA
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single strands of nucleotides
does the grunt work of protein synthesis |
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the genetic code
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method of information instruction and storage in DNA
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triplet
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sequence of 3 nitrogen bases that signal for a specific amino acid.
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gene
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functional unit of heredity. a gene contains a triplet code to encode for a protein.
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promotor
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start segment of a gene. needs to be unbound from a histone for the gene to be activated.
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DNA replication
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occurs in the nucleus. a copy of each parent gene must go into each daughter cell. requires DNA, helicases, nuleotides, and DNA polymerase.
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helicases
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unwind the dsDNA and break the H bond between the DNA strands. the exposed nitrogen bases are complimentary base paired to create a new strand of DNA. this is done by DNA polymerase.
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DNA polymerase
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enzyme needed to synthesize new DNA. copies the DNA by complementary base pairing. also acts as a "spell checker" to correct any nucleotide misplacement.
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mutations
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occur when nucleotide misplacement is not corrected. point mutations (one nucleotide wrong in a triplet) can cause diseases such as sickle cell anemia.
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gene activation
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once the histone moves away from the gene's promoter and the h bonds are broken between the complementary bases, the gene is activated.
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RNA polymerase
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binds to the promoter of a gene and starts synthesizing mRNA from DNA template strand by complementary base paring (A-U, T-A, C-G. G-C)
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coding strand
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contains the actual gene squence for the protein being made. complementary base paired with the template strand.
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template strand
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acts as a template for the RNA polymerases to make mRNA.
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transcription
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process which mRNA is transcribed from DNA template strand. RNA polymerase takes notes or transcribes the mRNA. done inside the nucleus. needs DNA, RNA polymerase, and nucleotides to make mRNA
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codon
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triplet code of nitrogen bases for mRNA to encode for a specific protein.
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immature mRNA
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includes codons for functional protein plus nunsense codons. nonsense codons must be edited out before the mRNA leaves the nucleus.
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introns
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nonsense regions of a gene or immature mRNA
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exons
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coding regions for functional proteins spliced together for mature mRNA
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splicing
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process of cutting out introns and ligating exons by nuclear enzymes
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translation
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translating the message from mRNA into an actual protein. occurs at the ribosomes in the cytoplasm. requires mRNA, tRNA, and rRNA to make the protein.
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transfer RNA (tRNA)
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brings the specific amino acid to the ribosome for protein synthesis.
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anticodon
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code on the tRNA to complement mRNA codon. the correct amino acid is carried by the tRNA that has a complementary base pairing of its anticodon with the mRNA's codon.
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