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50 Cards in this Set

  • Front
  • Back
What is radioactivity?
The ability of certain nuclides to

1. Undergo spontaneous uncontrolled decay.
2. emit penetrating radiation
Production of radionuclides are produced by what?
Irradiation of stable nuclides by subatomic particles such as deutrons or neutrons in a cyclotron or nuclear reactor.
What can be added to a number of compounds so that the compound is not altered physiologically?
Technetium99m
Length of time it takes for original number of atoms to disintegrate or decay to one half its original number?
Half life
Flash of light produced in a phosphor by radiation? What compound is most widely used?
Scinitillation

Sodium Iodide
sensitive device used to detect ionizing radiation by electronically measuring the light produced?
Scintillation detector
Examples of tracers in nuclear medicine?
1. Radioactive Iodine

2. Technetium-99m
Area in any organ where concentration is less than in surrounding tissue?
cold spot- cancer
Any organ where concentration is significantly greater than surrounding tissue.
Hot spot- brain tumor
Used in large percentage of studies because of the ideal energy and ideal half life?
Technetium-99m

140 kEv and 6 hour half life
When is Thyroid studied?

What is the procedure?

What are the results of this study?
suggested disturbance of function and size.
oral administration of iodine 123 collection
normal uptake at 10%-30% at 24 hours, hypothyroid anything lower hyperthyroid anything higher.
Brain indications:
early detection of brain tumors and/or metastases, subdural hematomas, CVAs, abscesses
Procedure for brain study?

Results?
2-mci of Tc 99m DTPA given with anterior images being taken every 3 seconds.

changes in distribution or flow shows CVA's and carotid artery obstructions.
What is nuclear medicine used for in bone studies?
Evaluates metastases, tumors, arthritis, paget's disease
What is the procedure for bone studies?

What are the results for bone studies?
IV injection of 20 mCi Tc99m labeled with phosphate complex. Total body scans performed 2 hours after injections.

hot spots indicate problems such as metastases and arthritis
What is nuclear medicine used to study the lungs for?
Pulmonary Emboli, CA, COPD
What is the prcocedure for studying the lungs in nuclear medicine?

What are the results of this study?
10-20 mCi of Xenon into breathing apparatus

normal- uniform distribution of radioactive gases with no activity after 3 minutes

abnormal- ventilation defects plus areas of nonradioactivity.
what kind of badges do nuc med techs wear?
ring badges
SPECT
single photon emission computed tomography
How does spect work?
may utilize one to three gamma camera detectors to produce tomographic or sectional images of a structure.
PET?
Positron Emission Tomography
How does PET work?
uses positron emissions form radionuclides to produce detailed functional images within the body
What does PET show?
1. blood flows

2. metabolic processes at cellular level
what does annhilation radiation result from?
positron decay
Positron emitters releases two identical ______ in exactly opposite directions
photons
Radionuclides have ______ halflives. They are produced in ___________.
short, cyclotrons.
Give 3 examples of radionuclides
Fluorine-18

radioactive water

Fluoride ions (FDG)
for glucose metabolism in the brain
fluorine 18
local cerebral blood flow
radioactive water
glucose utilization in the brain, heart, tumors or other tissues.
Fluoride ions.
what is PET used to measure?
human cellular, organ, or system function.
What clinical studies is PET used for?
1. detection of cancer whether it is benign or malignant. FDG

2. Monitoring effectiveness of drugs
What is myelograpy used to radiograph?
spinal cord and it's nerve root structures
what does the central nervous system consists of?
Brain and Spinal Cord
Where does the spinal cord end?
L1 or L2
Where is CSF produced?
ventricle
In myelography what type of injection is done?

Where is the injection given?
Introthecal

Subarachnoid space
Brains outer potion is called?

inner portions?
Cortex

White matter
What parts does the brain consists of?
Cerebrum, cerebellum, brain stem
what seperates the cerebrum into right and left hemispheres?
longitudinal fissure
spinal cord consists of inner _____ substance and outer _________ white substance.
gray, white
Where does the spinal cord extend from?
foramen magnum and medulla oblongota to L1 or L2.
What pointed structure does the spinal cord end in?
conus medularis
How many pairs of spinal nerves are there?
31
spinal nerves are tranmitted through what?
intervertebral and sacral foramina
Spinal nerves below the termination of the spinal below extend inferiorly through what?
vertebral canal
Spinal nerves below the termination of the spinal cord are referred to as?
cauda equina
inner sheath of brain and spinal cord?
pia matter
the middle sheath of the brain and spinal cord.
arachnoid
the strong outer covering of brain and spinal cord?
dura mater