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28 Cards in this Set

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___ infections result from hospital or hospital-like settings after 48 hours of admission or within 30 days after discharge

Nosocomial

The most common nosocomial infections are of what type?

Urinary tract infections




Some studies say pneumonia

What is the single most important measure in controlling nosocomial infections?

Hand washing

Immunosuppressants, steroids, antineoplastics and antacids all leave patients more susceptible to what?

Nosocomial infections

What are some common causes of altered mental status?

Alcohol, endocrine, insulin (hypoglycemia), oxygen, overdose, uremia (AEIOU)




Trauma, temperature, infection, psychiatric, stroke, shock, space occupying lesion (TIPS)

Most nosocomial UTIs are associated with what?

Catheters

What is the most common causative organism in nosocomial UTIs?

E. Coli

What is the treatment method for nosocomial UTIs if febrile and bacteremic?

IV broad spectrum abx: cipro, levofloxacin, 3rd generation cephalosporings, piperacillin-tazobactam (zosyn)

What is the treatment method for nosocomial UTIs without bacteremia?

Nitrofurantoins, TMP--SMX

What are some preventative measures that can be taken to prevent nosocomial UTIs?

Avoid catheter use or limit duration < 5 days. Proper insertion technique, drainage tube below the bladder.

What are the indications for a foley catheter?

Urinary retention, stage 4 decubitis ulcer on the buttocks

What is the leading cause of death from nosocomial infections?

Hospital acquired pneumonia

Hospital acquired pneumonia is usually due to pathogens entering the body in what way?

Microaspiration of oropharyngeal secretions

What organism involved in hospital acquired pneumonia produces the highest mortality rate?

Pseudomonas aeriginosa

What are some of the common microbes involved in nosocomial pneumonia (4)?

Pseudomonas aeruginosa, klebsiella, e. coli, acinetobacter

Why is ventilator associated pneumonia (VAP) increased with ET intubation?

Impaired cough reflex, no clearance of secretions, accumulation of bacteria above the inflated tube

Worsening or new pulmonary infiltrate PLUS either bacteremia or pleural fluid culture OR two of the following:


Fever


Leukocytosis


Purulent tracheobronchial secretions


Hypoxemia


+ Blood culture




These are the clinical criteria for diagnosing what kind of pneumonia?

Ventilator Associated Pneumonia (VAP)

Number one causative organism in VAP?

P. Aeruginosa followed by staph aureus

What are some preventative measures that can be taken to reduce the incidence of VAP?

HOB > 30 degrees, frequent oral care, frequent extubation evaluation, chlorohexadine rinse q6h while intubated.mupirocin BID x6 doses for MRSA eradication, carafate while intubated, NPO during intubation

Nosocomial pneumonia treatment for non-icu patients

2/3 generations cephalosporin with zithromax, moxiflaxacin




IV then PO with clinical improvement

Nosocomial pneumonia treatment for ICU patients

ABX with pseudomonas coverage: 3rd or 4th generation cephalosporins, carbapenems, fluoroquinolones, aminoglycoside, aztreonam

Treatment for nosocomial pneumonia in pts with increased risk of staph aureus

Vancomycin

Nosocomial pneumonia treatment in HIV pts

Bactrim (pentamidine if sulfa allergic)

Pre-operative hair removal (increases/decreases) surgical site infections

INCREASES

To prevent surgical site infections, antimicrobial prophylaxis should be given when?

Within 1 hour of skin incisions

Antibiotics before surgical colon procedures should include coverage for what organisms?

E. coli, bacteroides fragilis

Most common cause of IV catheter associated infections?

Staph epidermidis (coagulase negative staphylococci)

Where is the preferred IV site to prevent IVCA infections? What site should be avoided?

Preferred: Subclavian




Avoided: Femoral (increased risk in adults)