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35 Cards in this Set

  • Front
  • Back
B1 selective blockers
acebutol, betaxolol, esmolol, atenolol, metoprolol
N/S B blockers
propanolol, timolol, nadolol, pindolol, labetalol
B blocker toxicity
impotence, exacerbation of asthma, CV AE (bradycardia, AV block, CHF), CNS AE (sedation, sleep alterations), use with caution in diabetics
B blockers and cocaine OD
if you give a beta blocker you inhibit b2 vasodilation so you increase vasoconstriction
b1 block- decrease hr
exception is labetalol
B blocker uses
hypertension, angina pectoris, MI, SVT, CHF, glaucoma
MI necessities
b blocker, ACEI/ARB, Aspirin/plavix, statin
Morphine, oxygen, nitrates, aspirin
propanolol uses
thyrotoxicosis, anxiety disorders
nadolol use
esophageal varices
nonselective alpha blockers
phenoxybenzamine and phentolamine - used for pheochromocytoma
a1 selective blockers
prazosin, terazosin, doxazosin - used for HTN, urinary retntion in BPH
a1 selective blockers SE
1st dose orthostatic HTN, dizziness, HA
a2 selective blockers
mirtazapine- used for depression
epi and alpha blockade
beta 2 vasodilation is not suppressed, so you get a decrease in BP
epi selectivity
a1, a2, b1, b2 low dose selective for b1
NE selectivity
a1, a2 > b1
isoproterenol selectivity
b1 = b2
dopamine selectivity
d1 = d2 > beta > alpha
dobutamine selectivity
b1 > b2
amphetamine mechanism
indirect general agonist, releases stored catecholamines
ephedrine mechanism
indirect general agonist, releases stored catecholamines (same as amphetamine)
phenylephrine selectivity
a1 > a2
albuterol and terbutaline selectivity
b2 > b1
cocaine mechanism
indirect general agonist, uptake inhibitor
clonidine mechanism
centrally acting a-agonist, decreases central adrenergic flow
epi applications
anaphylaxis, glaucoma (open angle), asthma, hypotension
NE applications
hypotension (but decrease renal perfusion)
isoproterenol application
AV block (rare)
dopamine application
shock (increases renal perfusion), heart failure
dobutamine application
shock, heart failure cardiac stress testing
amphetamine application
narcolepsy, obesity, ADD
ephedrine application
nasal decongestion, urinary incontinence, hypotension
phenylephrine applications
pupil dilator, vasoconstriction, nasal decong
albuterol, terbutaline applications
asthma, stop uterine contractions
cocaine applications
causes vasoconstriction and local anesthesia
clonidine applications
hypertension, especially with renal disease (no decrease in blood flow to kidney), rebound hypertension