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35 Cards in this Set
- Front
- Back
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B1 selective blockers
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acebutol, betaxolol, esmolol, atenolol, metoprolol
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N/S B blockers
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propanolol, timolol, nadolol, pindolol, labetalol
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B blocker toxicity
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impotence, exacerbation of asthma, CV AE (bradycardia, AV block, CHF), CNS AE (sedation, sleep alterations), use with caution in diabetics
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B blockers and cocaine OD
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if you give a beta blocker you inhibit b2 vasodilation so you increase vasoconstriction
b1 block- decrease hr exception is labetalol |
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B blocker uses
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hypertension, angina pectoris, MI, SVT, CHF, glaucoma
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MI necessities
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b blocker, ACEI/ARB, Aspirin/plavix, statin
Morphine, oxygen, nitrates, aspirin |
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propanolol uses
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thyrotoxicosis, anxiety disorders
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nadolol use
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esophageal varices
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nonselective alpha blockers
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phenoxybenzamine and phentolamine - used for pheochromocytoma
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a1 selective blockers
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prazosin, terazosin, doxazosin - used for HTN, urinary retntion in BPH
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a1 selective blockers SE
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1st dose orthostatic HTN, dizziness, HA
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a2 selective blockers
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mirtazapine- used for depression
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epi and alpha blockade
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beta 2 vasodilation is not suppressed, so you get a decrease in BP
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epi selectivity
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a1, a2, b1, b2 low dose selective for b1
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NE selectivity
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a1, a2 > b1
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isoproterenol selectivity
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b1 = b2
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dopamine selectivity
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d1 = d2 > beta > alpha
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dobutamine selectivity
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b1 > b2
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amphetamine mechanism
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indirect general agonist, releases stored catecholamines
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ephedrine mechanism
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indirect general agonist, releases stored catecholamines (same as amphetamine)
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phenylephrine selectivity
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a1 > a2
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albuterol and terbutaline selectivity
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b2 > b1
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cocaine mechanism
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indirect general agonist, uptake inhibitor
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clonidine mechanism
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centrally acting a-agonist, decreases central adrenergic flow
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epi applications
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anaphylaxis, glaucoma (open angle), asthma, hypotension
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NE applications
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hypotension (but decrease renal perfusion)
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isoproterenol application
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AV block (rare)
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dopamine application
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shock (increases renal perfusion), heart failure
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dobutamine application
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shock, heart failure cardiac stress testing
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amphetamine application
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narcolepsy, obesity, ADD
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ephedrine application
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nasal decongestion, urinary incontinence, hypotension
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phenylephrine applications
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pupil dilator, vasoconstriction, nasal decong
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albuterol, terbutaline applications
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asthma, stop uterine contractions
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cocaine applications
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causes vasoconstriction and local anesthesia
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clonidine applications
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hypertension, especially with renal disease (no decrease in blood flow to kidney), rebound hypertension
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