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51 Cards in this Set
- Front
- Back
Basic hypothalamic functions
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nutrient and water intake, temperature/BP regulation, sleep-wake cycles and reproductive rhythms
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Hypothalmic divions
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preoptic area, anterior nucleus, suprachiasmatic nucleus, supraoptic nucleus, preoptic area, paraventricular nucleus, dorsomedial nucleus, ventromedial nucleus, posterior nucleus, mammillary nuclei, arcuate nucleus
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Preoptic area of hypothalamus
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regulates pituiatry gonadotropin secretion, reproductive/feeding/stereotyped locomotive behaviors
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Medial pre-optic
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cellular
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Lateral pre-optic
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fiber pathways
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Lateral zone of hypothalamus
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important in feeding behaviors
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Medial zone of hypothalamus
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supraoptic, suprachiasmatic, tuberal, mammillary
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Supraoptic/suprachiasmatic region
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water balance, circadian rhythm, body temperature
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Supraoptic nucleus
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ADH release
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Mangocellular Paraventricular Nucleus
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Oxytocin and ADH
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Parvocellular Paraventricular Nucleus
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CRH/AH, TRH
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Suprachiasmtic Nucleus
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Circadian Rhythm
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Anterior nucleus
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sleep and thermoregulation
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Role of Tuberal Region of Hypothalamus
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hormone secretion, satiety, emotional behaviors
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Structures of Hypothalamic Tuberal Region
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ventromedial, dorsomedial, arcuate nuclei, median eminence
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Ventromedial nucleus of hypothalamus
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satiety center
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Dorsomedial nucleus
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aggressive and emotional behavior
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Arcuate Nucleus
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endocrine & autonomic control
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Median Eminence
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endocrine control
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Function of Mammillary Region of Hypothalamus
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short term memory and blood pressure
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Structures of Hypothalamic Mammillary region
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medial mammillary nucleus, intermediate mammillary nucleus, lateral mammillary nucleus, posterior mammillary nucleus
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Medial Mammillary Nucleus
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histamine neruons, arousal
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Intermediate mammillary nucleus
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short term memory
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Korsakoff’s syndrome
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thiamine deficiency, issues with intermediate mammillary nucleus
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Posterior Mammillary Nucleus
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emotion & cardiovascular system
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Hypothalamic Blood Supply
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branches of circle of willis.
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Afferent fibers to Hypothalamus
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fornix, amygdala, medial forebrain bundle. Mammillary peduncle, thalamohypothalmotract, cortiohypothalamic tract, retinohypothalamic tract
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Fornix/amygdala → Hypothalamus
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limbic driven emotions
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Ascending medial forebrain bundle
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emotional responses
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Descending medial forebrain bundle
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emotional responses and autonomic functions
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Efferent fibers from Hypothalamus
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mammilothalamic tract, mammillotegmental tract, ascending/descending medial hypothalamic nuclei, lateral hypothalamic nuclei, intrinsic hypothalamic nuclei.
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Mammilolothalamic tract
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anterior nucleus. Mediates emotional responses
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Mammillotegmental tract
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projects to midbrain tegmentum. Mediates visceral autonomic responses
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Ascending medial hypothalamic nuclei
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emotional responses
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Descending medial hypothalamic nuclei
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emotional and autonomic responses
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Lateral hypothalamic nuclei
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synchronization of responeses mediated by projections in medial forebrain bundle
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Intrinsic Hypothalamic COnections
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tuberoinfundibular tract, supraopticohyopyseal tract
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Tuberoinfundibular tract
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dopamine neurons from arcuate nucleus that regulate prolactin release
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Supraopticohypophyseal tract
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projects the posterior pituitary
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Sensory Circumventricular Organs
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subfornical, organum vasculosum of lamina terminals, subcommissural organ, area posterma
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Secretory Circumventricular organs
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median eminence, neural lope of posterior pituitary, pineal gland
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Mangocellular
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ADH (Vassopressin) and Oxytocin. To posterior pituitary and release
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Hormones released by paraventricular nuclei
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TRH, CRH
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Hormones released by arcuate nuclei
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GnRH, GHRH
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Thermo-dissipation center
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anterior hypothalamic
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Thermo-conservation center
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posterior hypothalamus
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BP control
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solitary nucleus in brainstem but paraventricular hypothalamic nuclei can override signal
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Satiety center
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ventromedial nuclei
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Feeding center
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lateral hypothalamus
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Low Insuli:leptin
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anabolosim → increased food intake and weight gain
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High Insulin:Leptin
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catabolism → decreased food intake and weight loss
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