• Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off
Reading...
Front

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

A key: Read text to speech.a key

image

Play button

image

Play button

image

Progress

1/6

Click to flip

6 Cards in this Set

  • Front
  • Back
  • 3rd side (hint)
Epinephrine (MOA & PK)
MOA - Activation of sympathetic nervous system and all concomitant effects
PK - IV; very short half-life (minutes); degraded rapidly by COMT and MAO; Catechol moiety prevents ready absorption and CNS penetration
Epinephrine (CU & T)
CU - Glaucoma (increase outflow); anaphylaxis; hypotension; heart failure; reduced local blood flow; severe asthma
T - Arrhythmias, hypertension, cerebral hemorrhage, tachycardia, anxiety
Norepinephrine (MOA & PK)
MOA - Activation of sympathetic nervous system and all concomitant effects but more specific effect on a1 and B1
PK - IV; very short half-life (minutes); degraded rapidly by COMT and MAO; Catechol moiety prevents ready absorption and CNS penetration; a1=a2; B1>>B2
Norepinephrine (CU & T)
CU - Hypotension; heart failure
T - Arrhythmias, hypertension, cerebral hemorrhage, tachycardia, anxiety, reflex bradycardia increased risk of cardiac ischemia
Dopamine (MOA & PK)
MOA - low dose: potent dopamine receptor agonist, dilation of renal and coronary vascular beds; medium doses: speeds heart rate (beta); high doses: produces vasoconstriction (alpha); also causes release of catecholamines
PK - IV; very short half-life (minutes); degraded rapidly by COMT and MAO; Catechol moiety prevents ready absorption and CNS penetration; D1=D2 >>B>>a
Dopamine (CU & T)
CU - Hypotension; heart failure especially useful for cardiogenic and hypovolemic shock which are associated with low cardiac output and compromised renal function
T - Arrhythmias, hypertension, cerebral hemorrhage, tachycardia, anxiety, reflex bradycardia increased risk of cardiac ischemia