Nonglial And Mixed Glial Brain Tumors

Front 1

Primary CNS lymphoma

Back 1

Immunocompromised patients
almost always non-hodgkins B cell lymphoma
Small blue cell tumor
hyperdensity on noncon CT and hypointense on T2.
Usually located either adjacent to the ventricular system or along the leptomeninges.
Some enhancement seen in all lesions.
Subependymal spread common and bihemispheric involvement via the corpus callosum.

Front 2

Ganglioglioma and gangliocytoma

Back 2

Ganglioglioma composed of both glial cells adn differentiated neurons. Gangliocytoma are pure neuronal tumors.
Most occur younger than 30
Most common location of Ganglioglioma is the temporal lobe
Most common location of Gangliocytoma is floor of the third ventricle.
On CT are most often hypo or iso dens, well-circumscribed lesions with little associated mass effect or surrounding edema.
On MR are hypo or iso intense on T1 and hyperintense on T2.

Hint 2

Ganglioglioma is most common tumor seen in patients with chronic temporal lobe epilepsy.

Front 3

Desmoplastic Infantile ganglioglioma

Back 3

Variant of ganglioglioma. Very large heterogeneous mass and is almost aways seen in first year of life. Affects boys more than girls.
Rapidly expanding head circumference is most common finding.
On imaging- large periopheral heterogeneous mass with both cystlike and solid components.
Intense enhancement of the "desmoplastic" soft tissue is the rule.

Front 4

Dysembryoplastic neuroepithilial tumor

Back 4

Most common tumor associated with medically refractory partial complex seizures.
Most patients between 10 and 30 years old
Peripheral in location and involves cortical gray matter.
Some lesions may produce a "soap bubble" appearance with exophytic extension beyond the normal cortical gray matter margin.

Front 5

Supratentorial primitive neuroectodormal tumor

Back 5

Primarily noted in early childhoold period.
Present with symptoms of increased ICP and seizures.
Large well demarcated heterogeneous mass with both solid and cystlike areas within the deep cerebral white matter.
A periventricular or intraventricular location with hydro is common.
On CT, calcification is common.
Regions of hemorrhage and necrosis also common.

Hint 5

Arise from bipotential precursor cells of the germinal matrix with the ability to differentiate along either glial or neuronal cell lines.