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14 Cards in this Set

  • Front
  • Back
Small lymphocytic lymphoma
-B cell
- like CLL with focal mass, low grade
(CLL older adults, lymphadenopathy, hepsplenomegaly, smudge cells, warm autoimmune hemolytic anemia)
Follicular lymphoma
-B cells
- 14:18 bcl-2
-most common in adults and difficult to cure
Diffuse large cell lymphoma
-80% older adults 20% children
-B cells(80%) T cells (20%, mature
-agressive but 50% curable
Mantle cell lymphoma
-B cells
-(11:14)bcl-1, cyclin D
-CD 5 poor prognosis
Lymphoblastic lymphoma
-most common in Children
-T cells (immature)
-most commonly presents with ALL and mediastinal mass, very aggressive

(ALL children, lymphoblasts and most responsive to therapy- may spread to CNS and testes)
Burkitt's Lymphoma
-B cells
- c-myc 8:14
-"starry sky"- lymphocytes with macrophages in between
-associated with EBV- endemic: jaw lesion
-pelvis and abdomen- sporadic form
What are the B cell lymphomas?
small lymphocytic
diffuse large cell (80%)
mantle cell

What is the MC lymphoma in children?
lymphoblastic lymphoma
what is the MC lymphoma in adults?
follicular lymphoma
what are the three lymphomas with translocations?
-follicular (14:18)bcl-2
-mantle (11:14)bcl-1, cyclin D
-Burkitt's (8:14)c-myc
Acute lymphoblastic leukemia
most resp to therapy and may spread to CNS and testes
Acute myeloblastic leukemia
Auer rods, myeloblasts, adults
Chronic lymphocytic leukemia
-older adults, lymphadenopathy and hepatosplenmegaly
-few symptoms
-indolent course
-warm autoimmune hemolytic anemia

-similar to small lymphocytic lymphoma
Chronic myelocytic leukemia
-myeloid stem cell proliferation
-increased neutrophils and metamyelocytes
-(9:22 philidelphia chromosome bcr-abl)
-low leukocyte alkaline phosphatase (unlike leukemoid reaction)

-may accelerte to AML "blast crisis"