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126 Cards in this Set
- Front
- Back
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Generic name of SCH
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Anectine
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Generic name of rocuronium
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zemuron
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generic name of atracurium
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tracrium
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generic name of cisatracurium
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nimbex
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generic name of vec
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norcuron
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generic name of pipercuronium
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arduan
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induction dose of SCH
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1-1.5 mg/kg
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induction dose of Roc
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0.6-1.2
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Generic name of SCH
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Anectine
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induction dose of Mivacurium
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0.15-0.25mg/kg
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Generic name of rocuronium
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zemuron
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induction dose of Vecuroinum
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0.1mg/kg
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generic name of atracurium
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tracrium
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generic name of cisatracurium
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nimbex
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generic name of vec
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norcuron
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generic name of pipercuronium
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arduan
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induction dose of SCH
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1-1.5 mg/kg
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induction dose of Roc
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0.6-1.2
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induction dose of Mivacurium
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0.15-0.25mg/kg
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induction dose of Vecuroinum
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0.1mg/kg
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induction dose of atracurium
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0.3-0.5
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induction dose of cis-atracurium
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0.2 mg/kg
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pancuronium induction dose
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0.1
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d-tubo induction dose
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0.6 mg/kg
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onset of sux
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30-60 sec
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onset of roc
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45-90 sec
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onset of mivacurium
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2-3 min
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onset of atracurium
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2-4 min
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onset of d-tubo
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3-5 min
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onset of cis-atracurium
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2-4 min
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induction dose of atracurium
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0.3-0.5
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induction dose of cis-atracurium
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0.2 mg/kg
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pancuronium induction dose
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0.1
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d-tubo induction dose
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0.6 mg/kg
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onset of sux
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30-60 sec
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onset of roc
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45-90 sec
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onset of mivacurium
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2-3 min
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onset of atracurium
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2-4 min
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onset of d-tubo
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3-5 min
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onset of cis-atracurium
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2-4 min
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onset of pancuronium
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3-5 min
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duration of sux
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5-8 min
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duration of roc
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30-40 min
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duration of mivacurium
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12-18 min
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duration of vec
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30-40 min
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duration of atracurium
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30-40 min
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duration of cis-stracurium
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40-60 min
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duration of panc
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45-65
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d-tubo duration
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60-90 min
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which are histamine releasers
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atracurium, sux, mivacurium, d-tubo
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what things up regulate AChR
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upper or lower motor neuron lesions
muscle trauma burns immobilization sepsis/inf |
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what things down regulate AChR
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myasthenia gravis
organophosphate poisoning chronic cholinesterase inhibition |
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what meds decrease neuromuscular blocking effects
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corticosteroids
lasix at high doses phenytoin methylxanthines |
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order of muscles that are blocked
first to last |
adductor pollices
orbicular laryngeal diaphragm |
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which are benzoisoquinlinium
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atracurium
cisatracurium mivacurium histamine release reflects presence of tertiary amine |
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maintenance of atracurium
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0.1-0.1
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priming dose of atracurium
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3-5 mg
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atracurium metabolism
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hoffman
plasma esterases |
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hoffman dependent on
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ph and temp
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cis metabolism
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hoffman
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primary route of elimination is metabolism for which
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suc
atracurium cis mivacurium |
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biliary excretion is the primary elimination for
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vec and roc
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renal is primary metabolism for
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d-tubo
metocurarine panc gallamine pipercuronium |
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mivacurium is elimated by
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plasma cholinesterases
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which rarely used other than defasiculation due to large histamine release
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d-tubo
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maintenance of mivacurium
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0.01-0.1mg/kg
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maintenance dose for panc
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.01-0.5mg/kg
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which increase HR secondary to combination of ganglionic blockade and ihibition of reuptake of NE
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panc
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maintenance of roc
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0.06-.6mg/kg
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maintenance of vec
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0.01-0.05mg/kg
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which anticholinergics crosses BBB
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physostigmine
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does atropine cross BBB
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yes
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dose of atropine with edrophonium
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0.01mg/kg
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dose of atropine with neostigmine
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0.02mg/kg
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duration of atropine
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30 min
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onset of atropine
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1 min
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dose of glyco
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0.01 mg/kg with neo or pyrido
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onset of glyco
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2-3 min
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duration of glyco
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2-3 hours HR effect
up to 7 anticholinergic effect |
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edrophonium dose
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0.5-1.0 mg/kg
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onset of edrophonium
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1-2 min
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what should you give before giving edrophonium and why
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atropine
to prevent brady |
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duration of edrophonium
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10 min
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dose of pyrido
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0.2mg/kg
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max dose of pyrido
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30 mg
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peak of pyrido
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6-15 min
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duration of pyrido
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120-180 min
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which anticholinesterase most potent
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neo
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dose of neo
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0.03-0.07mg/kg
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onset of neo
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6 min
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peak of neo
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6-15 min
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dur of neo
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60-120 min
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how many achetylcholine receptors occupied before fade seen
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75%
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how many receptors occupied to completely suppress twitch
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95%
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which produce hypotension
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suc
d-tubo metocurarine |
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which causes hypertension
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panc
gallamine |
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which produces brady and why
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suc
mimics action of ACH and directly stimulates M receptors of SA node |
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which produces autonomic ganglionic blockade
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d-tubo
metocurarine |
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does pcn change degree of sux block
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no
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does VA change degree of sux block
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no
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does LA change sux block
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yes
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does anticonvulsants change degree of nondepolarizers block
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yes, decreases
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how do burn inj change to degree of nondepolarizers block
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decreased
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what decreases normal metabolism of sux
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liver disease
preg neonate |
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which drugs irreversibly alter metabolism of sux
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echothiophate
pesticides |
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normal dibucaine number
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80
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how is sux terminated
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psuedocholinesterases
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mechanism for myalgia side effect
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shif of Ca intracellular
muscle spindle damage asynchronous muscle contractions |
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how long and how much increased intraocular pressures with sux
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5-15mmHG for 10 minutes
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normal K increase with sux
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0.5meq/l
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does LA change sux block
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yes
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does anticonvulsants change degree of nondepolarizers block
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yes, decreases
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how do burn inj change to degree of nondepolarizers block
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decreased
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what decreases normal metabolism of sux
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liver disease
preg neonate |
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which drugs irreversibly alter metabolism of sux
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echothiophate
pesticides |
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normal dibucaine number
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80
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how is sux terminated
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psuedocholinesterases
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mechanism for myalgia side effect
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shif of Ca intracellular
muscle spindle damage asynchronous muscle contractions |
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how long and how much increased intraocular pressures with sux
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5-15mmHG for 10 minutes
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normal K increase with sux
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0.5meq/l
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list EKG effects of hyperkalemia
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peaked T
ST depression prolonged PR loss of P QRS widening |
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do liver disease have a abnormal dibucaine number
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no
measures quality not quanity |
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how many receptors blocked if TV >5ml/kg
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80
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how many receptors blocked if no fade in TOF
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70
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how many receptors blocked if head lift
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50
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why does reversals sometimes augment phase I block
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also inhibits psuedocholinesterases which prolongs depolarizers
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