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13 Cards in this Set

  • Front
  • Back
Odds Ratio of 1 means?
no difference in the probability
Odds Ratio of more than 1 means?
higher probability
incidence of a disease can only be shown by what sorta study?
prospective study
Retrospective studies ____ show the incidence of a disease.
cannot
What are the factors in risk assessment?
True Risk Factors
Modifying factors
Predisposing local factors
Other associated factors.
Confounding factors.
Define true risk factor
“A factor exposure to which is related to the onset of the disease
Define Modifying factors
“A situation, condition or characteristic of a patient that can alter the progress of a disease (prognosis), once this has been initiated.”
Define Predisposing local factors
A situation, condition or characteristic which predisposes for the effect of a known risk factor
Define Confounding factors
A situation, condition or characteristic that appears to be associated with a disease, without really having a role in the pathogenesis and progression of the disease
Potential Mechanisms for Diabetes induced Host Susceptibility?
• Impaired blood flow to periodontium
• Depressed neutrophil function
• Genetic susceptibility
– LPS response genes >> Increased inflammation
• Enhanced monocytic responses to LPS
– increased secretion of PGE2, IL-1b and TNFa
Complete the following for periodontal diseases:

True Risk Factors
Modifying factors
Predisposing factors
Other associated factors
Confounding factors.
True Risk Factors
- Bacterial Plaque

Modifying factors
- Diabetes Mellitus
- Smoking

Predisposing factors
- Overhanging Restorations
- Subgingival Restorations
- Calculus
- Furcation Involvement

Other associated factors
- Osteoporosis
- Psychosocial factors
- Obesity

Confounding factors
- age
- SES
Which are the main types of Diabetes mellitus and how do they differ?
Type 1
insulin dependent

type 2
insulin independent
What is the influence of Diabetes Mellitus on Periodontal disease?
Impaired blood flow to periodontium
Slows down the healing
Depressed neutrophil function
Genetic susceptibility
Enhanced monocytic responses to LPS