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5 Cards in this Set

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  • Back
What are the four stages of neurulation?
Competence
Specification
Commitment
Differentiation
What are the two types of Neurulation?
Primary
Secondary
What is primary neurulation?
Neuroblasts aggregate to form neural plate which folds to form neural tube
What is secondary neurulation?
A condensation of mesencymal cells form a solid, dense tube, the medullary cord, that is later hollowed out to form the neural tube. [Happens in posterior]
What are the 4 stages of primary neurulation?
Formation of the neural plate: BMP4 induces ectodermal cells to become neural plate.
- Shaping of the neural plate: Cells are signaled to become columnar and the groove forms along with the folds due to the MHP [medial hinge point]

regions and two DLHP [dorsolateral hinge point regions].
- Bending of the neural folds: Epidermis expands putting pressure on the neural plate. Its folds fold along, creasing at the hinge point regions

until both folds meet.
- Closure of the neural tube: The folds adhere to each other and cells merge.