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11 Cards in this Set

  • Front
  • Back

Acetylecholine (ACH) --

Post synaptic-- excitoatory


Precursoer ---- Choline + Acetyle Coa


Rate-Limiting step--- CAT--- CholineAcetyletransferase




REmoval Mechanism - ACHase (acetylecholinease)




small





Glutamate

Excitatory


Glutamine


Glutaminase


Transporter (removal mechanism)


small

GABA

Inhibitory


Glutamate (precursor)


limiting step in synthesis - GAD -- (glutamic acid decarboxylase)


transporter (removal mechanism)

Glycine

Inhibitory


Serine (precursor)


phosphoserine ( limiting)


transporter(removing mech)


small



Catecholamines (such as epinephrine , norepinephrine and dopamine)

Excitoatory


Tyrosine


tyrosine hydroxylase (limiting synt.)


transporter (mechanism removal), MAO, COMT


small , dense ,





Serotonine (5-HT)

Excitatory


Tryptophan


tryptophan hydroxylase


transporter (MAO)


large, dense

Histamine

Excitatory


Histidine (precursor)


histidine decarboxylase(limiting synt)


transporters


Larger dense core

ATP

Excitatory


ADP (precursor)


Mitochondrial oxidative phsophorylation; glycolysis (limiting synth.)




Hydrolysis to AMP and adenosine( removal)




small clear





Neuropeptides

excitatory and inhibitory


Amino acid (protein synthesis= precursor)


Synthesis and transport


Proteases


Large, dense core

Endocannabinoids

inhibits inhibition


membrane lipid- precursor


Enzymatic modification of lipids (limiting synth.)


Hydrolysis by FAAH(removal mechanism)


none -- no visible type





Nitric oxide

Excitatory and inhibitory


Arginine (precursor)


nitric oxide synthase (limiting synth.)


Spontaneous oxidation(removal mechanism)


None -- no vesicle type