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6 Cards in this Set
- Front
- Back
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Distal Axon Degeneration (DAD)
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exogenous toxins, target axonal transport, dying-back, resembles Wallerian degeneration (myelin sheath breaks down along with axon), muscle atrophy, gradual insidious onset, stocking-glove sensory/motor loss
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Segmental (non-uniform) myelinopathy
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caused by AIDP, affects internodal mylein and schwann cells themselves, immune attack on PNS myelin, end up with short internodes of myelin
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Diffuse (uniform) myelinopathy
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CMT!!onion bulb formatiosn from Schwann cells trying to remyelinate
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Neuronopathy
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cell body of neuron, herpes, polio, drug induced (i.e. pyridoxine-induced), , dorsal root ganglion particularly vulnerable, motor OK, sensory affected, NO REGENERATION
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focal (mononeuropathy) vs. multifocal
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focal - ischemia, infiltration i.e. tuberculoid leprosy,
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classes of nerve injury
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Praxia OK, tmesis BAD
1) neurapraxia -sit on leg funny 2) axonotmesis - crush, itnerupt axon, schwann cell basal lamina ok 3) neurotmesis - axon severed |
