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39 Cards in this Set
- Front
- Back
with some exceptions, all neuropathies are dependent on what?
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length dependent
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most common cause of neuropathy and its pattern?
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diabetic neuropathy with mixed involvement
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second most common cause of neuropathy?
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hereditary sensory motor defects
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most common presentation of hereditary sensory autonomic neuropathy?
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loss of sensation of pain
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acute motor axonal neuropathy?
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freq. associated with campylobacter jejuni infection, where motor is defect, but sensory is normal
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elevated GQ1 antibody indicate?
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miller fisher variant of AMAN
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tx. of choice for acute neuropathies?
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IV immunoglobulins at the right time; some do worse if administered too early
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"double crush"?
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C6 radiculopathy superimposed over carpal tunnel
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most common location of peroneal nerve injury?
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fibular head, where it is most shallow
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meralgia parasthetica?
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compression of lateral cutaneous nerve of thigh or lateral femoral cutaneous nerve
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mononeuropathy multiplex?
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mononeuropathy in various areas at the same time, mostly seen in diabetics
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which protein is defective in muscular dystrophies?
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dystrophin
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disease that affects the flexor muscles more so than the extensor muscles?
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inclusion body myositis, most often seen in older pop.
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facial and shoulder weakness, and waddling gait indicative of?
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fascioscapulohumeral dystrophy, often associated with cardiac problems as well
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hatchet face, level clavicle and axillary folds indicate?
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myotonic dystrophy
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often dx. when pt. has trouble being weaned from the ventilator?
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acid maltase deficiency
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myoglobinuria and cardiomyopathy common manifestations?
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muscle carnitine deficiency
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hypokalemic periodic paralysis often found after? (4)
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excercise, high carb meal, EtOH, cold exposure
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tx. of K related paralysis?
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diamox
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difference between hypo and hyperkalemic periodic paralysis?
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hyper can have attack after mild excercise
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ICU myopathy often associated with what?
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motor-sensory neuropathy associated
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major difference bet. polymyositis and dermatomyositis?
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derma has rash or color change in skin
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EMG findings with myopathies (4)?
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brief low voltage units, increased recruitment, interference, absent fasciculations
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biopsy findings in myopathies? (5)
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necrosis, fatty change, central nuclei, round cells, ragged red fibers
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upper plexus roots called what and contain which roots?
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C5-C7 called Erb's or Duchenne, arm abducted, int. rotated, and hand in fist
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lower plexus roots involve which roots and called what?
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C8 and T1, Klumpke's; weak flexors
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bilateral and recurrent plexitis?
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parsonage-turner syndrome
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nerve and EMG findings in plexopathies?
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nerve finding are normal for first 14 days, EMG abnormal from beginning
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nerve conduction study results in myasthenia gravis?
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decreasing response (10% or greater), and "jitter" in single fiber EMG
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tensilon test?
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IV edrophonium overcoming weakness in myasthenia gravis
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which tumor commonly associated with MG?
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thymus tumor
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meds that slow breakdown of acetylCoA?
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mestinon or pyridostigmine
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best measure of respiration in MG?
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forced vital capacity; less than one liter indicates ventilator
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difference in lambert eaton and MG?
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absence of bulbar involvement and association with small cell lung ca, also get stronger with excercise
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three forms of botulism?
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food, wound, and infantile
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EMG studies on ALS?
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decreased recruitment and increased motor unit size
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only tx. option for ALS?
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riluzole
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difference in primary lateral sclerosis vs. ALS?
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primary lateral sclerosis in exceptionally slow progression
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excessive muscle activity resulting in cramping and stiffness?
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neuromyotonia
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