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39 Cards in this Set

  • Front
  • Back
with some exceptions, all neuropathies are dependent on what?
length dependent
most common cause of neuropathy and its pattern?
diabetic neuropathy with mixed involvement
second most common cause of neuropathy?
hereditary sensory motor defects
most common presentation of hereditary sensory autonomic neuropathy?
loss of sensation of pain
acute motor axonal neuropathy?
freq. associated with campylobacter jejuni infection, where motor is defect, but sensory is normal
elevated GQ1 antibody indicate?
miller fisher variant of AMAN
tx. of choice for acute neuropathies?
IV immunoglobulins at the right time; some do worse if administered too early
"double crush"?
C6 radiculopathy superimposed over carpal tunnel
most common location of peroneal nerve injury?
fibular head, where it is most shallow
meralgia parasthetica?
compression of lateral cutaneous nerve of thigh or lateral femoral cutaneous nerve
mononeuropathy multiplex?
mononeuropathy in various areas at the same time, mostly seen in diabetics
which protein is defective in muscular dystrophies?
dystrophin
disease that affects the flexor muscles more so than the extensor muscles?
inclusion body myositis, most often seen in older pop.
facial and shoulder weakness, and waddling gait indicative of?
fascioscapulohumeral dystrophy, often associated with cardiac problems as well
hatchet face, level clavicle and axillary folds indicate?
myotonic dystrophy
often dx. when pt. has trouble being weaned from the ventilator?
acid maltase deficiency
myoglobinuria and cardiomyopathy common manifestations?
muscle carnitine deficiency
hypokalemic periodic paralysis often found after? (4)
excercise, high carb meal, EtOH, cold exposure
tx. of K related paralysis?
diamox
difference between hypo and hyperkalemic periodic paralysis?
hyper can have attack after mild excercise
ICU myopathy often associated with what?
motor-sensory neuropathy associated
major difference bet. polymyositis and dermatomyositis?
derma has rash or color change in skin
EMG findings with myopathies (4)?
brief low voltage units, increased recruitment, interference, absent fasciculations
biopsy findings in myopathies? (5)
necrosis, fatty change, central nuclei, round cells, ragged red fibers
upper plexus roots called what and contain which roots?
C5-C7 called Erb's or Duchenne, arm abducted, int. rotated, and hand in fist
lower plexus roots involve which roots and called what?
C8 and T1, Klumpke's; weak flexors
bilateral and recurrent plexitis?
parsonage-turner syndrome
nerve and EMG findings in plexopathies?
nerve finding are normal for first 14 days, EMG abnormal from beginning
nerve conduction study results in myasthenia gravis?
decreasing response (10% or greater), and "jitter" in single fiber EMG
tensilon test?
IV edrophonium overcoming weakness in myasthenia gravis
which tumor commonly associated with MG?
thymus tumor
meds that slow breakdown of acetylCoA?
mestinon or pyridostigmine
best measure of respiration in MG?
forced vital capacity; less than one liter indicates ventilator
difference in lambert eaton and MG?
absence of bulbar involvement and association with small cell lung ca, also get stronger with excercise
three forms of botulism?
food, wound, and infantile
EMG studies on ALS?
decreased recruitment and increased motor unit size
only tx. option for ALS?
riluzole
difference in primary lateral sclerosis vs. ALS?
primary lateral sclerosis in exceptionally slow progression
excessive muscle activity resulting in cramping and stiffness?
neuromyotonia