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15 Cards in this Set
- Front
- Back
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What is Multiple scelerosis?
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Neurological lesions separated by space and time. More than one area of the CNS is involved in more than one attack.
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What is the best INITIAL test for multiple Scelerosis?
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MRI.
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When do we use Lumbar puncture in Multiple scelerosis?
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-When MRI result are equivocal and non reliable to reach a diagnosis.
-"Oligoclonal bands" |
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Multiple sclerosis treatment?
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-During relapses I.V steroids
-Inbetween attacks: (slow progress of the disease. a)Beta 1a Interferon( Avonex) b)Beta 1b Interferon( Betaseron) c)Copolymer A (Copaxone) Chronic progressive MS: No effective drug. |
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Managment of Multiple sclerosis patient+ pain
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Phenytoin
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Managment of Ms patient + Spasticity
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Baclofen or Zanaflex.
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Managment of Ms patient+ fatigue
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Amantadine or provigi.
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Hot climate effect on MS
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Promotes weakness.
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What is the most efficient anti-parkinson's drug?
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L-dopa/Carbidopa
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What is the side effects of L-dopa/carbidop( Sinemet)
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-Acute:
a)Psychosis: Due to increased level of dopamine. b)Hypotension. c)GIT upset. Late side effects /response fluccations a)On/off symptoms b)Dyskenisea: Abnormal Movements. c)Akinesia: Restless. |
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How do you treat the functioning or reasonably functioning parkison's patient?
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a)Age>60------> Amantadine.
b)Age<60------>Anti-cholinergic which would may caue confusion, dry mouth, urine retention. |
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How do you treat the non-functioning parkinson's patient?
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L-dopa/carbidop.
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What to do if patient starts to exhibit L-dopa/cabridop side effects?
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Add:
1)Dopamine agonists Pergolide, Pramipexole,Ropinirole. 2)COMT inhibitor : Tolcapone. Dopamine agnoists is better to than COMT. |
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What the drug that can slow the progress of parkinson's disease?
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MAO-B inhibitor: Selegline.
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How to Diagnois huntington Chorea?
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-presentation:
a)Abnormal movments(chorea) b)Abnormal Behavior. C)Postive family history (autosomal dominant) -Tests: a)Chromosomal analysis:Huntington protien on chromsome4 b)CT may show boxcar ventricle "enlarged" (from loss of caudate)with cortical atrophy |
