Neurology Shelf Exam

Front 1

Behcet disease

Back 1

aseptic meningoencephalitis

Front 2

Marchiafava-Bignami syndrome

Back 2

frontal-type dementia, seizures, pyramidal signs, focal demyelination and necrosis of the corpus callosum

Front 3

Lennox-Gastaut syndrome

Back 3

atonic, tonic, myoclonic, GTC, absence seizures, MR, slow 1-2hz spike and wave EEG findings, tx: valproic acid, lamotrigine, felbamate

Front 4

Benign rolandic epilepsy

Back 4

Simple partial invovling mouth and face, GTC, nocturnal preponderance of szs, centrotemporal spikes on EEG, tx: carbamazepine

Front 5

Apraxia

Back 5

inability to perform a learned motor task despite preservation of necessary basic motor, sensory, cognitive capacities

Front 6

Agnosia

Back 6

inability to recognize objects despite preservation of the basic sensory modalities being used

Front 7

Alexander disease

Back 7

glial fibrillary acidic protien defect, rosenthal fibers on bx, macrocephaly, demyelination of the CNS

Front 8

Canavan disease

Back 8

aspartoacylase deficiency, macrocephaly, demyelination of the CNS

Front 9

Anti-Hu antibodies

Back 9

sensory neuronopathy - paraneoplastic disorder (SCLC) a/w paraneoplastic encephalomyelitis, ataxia, and autonomic neuropathies

Front 10

Causes of sensory neuropathy

Back 10

Sjogren, pyridoxine intoxication, chemo (cisplatin)

Front 11

Pancerebellar syndrome

Back 11

ataxia, dysarthria, nystagmus - underlying malignancy is gynecological

Front 12

Mytonic dystrophy

Back 12

causes frontal balding, diabetes, GI sxs, cataracts, cardiac arrythmias - AD inheritance, triplet repeat in DMPK gene, EMG shows myotonic discharges

Front 13

Mononeuropathy multiplex

Back 13

multiple, sequential mononeuropathies, each affecting a single peripheral nerve

Front 14

Subfalcine herniation

Back 14

compression of ACA with leg weakness

Front 15

Uncal herniation

Back 15

i.l. CN III palsy. compression of c.l. cerebral peduncle against free edge of tentorium --> i.l. hemiparesis (Kernohans notch phenomenon)

Front 16

Right INO

Back 16

inability to adduct the right eye in left lateral gaze plus nystagmus of the abducting left eye, caused by lesion of MLF

Front 17

One-and-a-half syndrome

Back 17

lesion involving the PPRF, CNVI and adjacent i.l. MLF --> only eye movement present in horizontal plane is abduction of left eye (for right one and a half)

Front 18

bilateral LMN facial weakness, lymphocytic meningitis, cranial neuropathies including optic neuropathy with RAPD

Back 18

sarcoidosis

Front 19

hypomelanotic eye lesions, cortical tubers, subependymal giant cell astrocytomas

Back 19

tuberous sclerosis

Front 20

polyradiculitis with flaccid paraparesis, sacral pain, paresthesias, sphincter dysfunction or cauda equina syndrome cause in an immunocompromised individual

Back 20

CMV

Front 21

ICH caused by HTN - areas in order of decreasing frequency

Back 21

basal ganglia, thalamus, pons, cerebellum

Front 22

Carbamazepine side effects

Back 22

hyponatremia, agranulocytosis, SJS

Front 23

parkinsonism, supranuclear impairment of eye movements with difficult vertical gaze, impaired postural reflexes

Back 23

progressive supranuclear palsy

Front 24

ataxia, ophthalmoplegia, areflexia (variant of GBS), anti-GQ1b antibodies

Back 24

Miller-Fisher Syndrome

Front 25

most sensitive MRI sequence for presence of blood breakdown products

Back 25

susceptibility

Front 26

REM sleep disorders

Back 26

synucleinopathies - PD, lewy body dementia, multiple system atrophy

Front 27

Vitamin E deficiency

Back 27

ataxia, myelopathy, polyneuropathy