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28 Cards in this Set

  • Front
  • Back
Phenobarbital
Mech: na block gaba/cl incr.
Met: hepatic *longest T1/2
IV
Side: sedation, hyperactivity
Phenytoin
Mech: Na block
Met: hepatic NONLINEAR
IV
Side: gingival hyperplasia, bone marrow suppression
Primidone
Mech: na, gaba/cl
Met: hepatic
Side: sedation, hyperactivity
Ethosuximide
Mech: T-Ca block
Met: hepatic
Side: GI upset, headache
Carbamazepine
Mech: Na block
Met: hepatic AUTO INDUCTION
Side: decr Na, WBC, hepatitis
Valproate
Mech: Na-, gaba/cl+, T-ca -
Met: hepatic
IV
Side: Thrombocytopenia, hepatitis, pancreatitis
Felbamate
Mech: Na -, glutamate -
Met: hepatic
Side: aplastic anemia
Gabapentin
Mech: na-, gaba/cl+, glut -
Met: EXCRETEDKIDNEY*short T1/2
Side: sleepiness
Lamotrigine
Mech: na-, glut-
Met:hepatic
Side: rash (increased with valproic acid)
Topiramate
Mech: na-, gaba/cl+, glut-
Met: hepatic
Side: cognitive slowing, renal stones
Tiagibine
Mech: gaba/cl+
Met: hepatic
Side: Dizzy, somnolence
Oxcarbazepine
Mech: na+
Met: hepatic
Side: hyponatremia
Zonisamide
Mech: na+, ca-
Met: hepatic
Side: Kidney stones
Levetiracetam
Mech: ?
Met: EXCRETED KIDNEY
Side: sleepy
Phenobarbital
Mech: na block gaba/cl incr.
Met: hepatic *longest T1/2
IV
Side: sedation, hyperactivity
Phenytoin
Mech: Na block
Met: hepatic NONLINEAR
IV
Side: gingival hyperplasia, bone marrow suppression
Primidone
Mech: na, gaba/cl
Met: hepatic
Side: sedation, hyperactivity
Ethosuximide
Mech: T-Ca block
Met: hepatic
Side: GI upset, headache
Carbamazepine
Mech: Na block
Met: hepatic AUTO INDUCTION
Side: decr Na, WBC, hepatitis
Valproate
Mech: Na-, gaba/cl+, T-ca -
Met: hepatic
IV
Side: Thrombocytopenia, hepatitis, pancreatitis
Felbamate
Mech: Na -, glutamate -
Met: hepatic
Side: aplastic anemia
Gabapentin
Mech: na-, gaba/cl+, glut -
Met: EXCRETEDKIDNEY*short T1/2
Side: sleepiness
Lamotrigine
Mech: na-, glut-
Met:hepatic
Side: rash (increased with valproic acid)
Topiramate
Mech: na-, gaba/cl+, glut-
Met: hepatic
Side: cognitive slowing, renal stones
Tiagibine
Mech: gaba/cl+
Met: hepatic
Side: Dizzy, somnolence
Oxcarbazepine
Mech: na+
Met: hepatic
Side: hyponatremia
Zonisamide
Mech: na+, ca-
Met: hepatic
Side: Kidney stones
Levetiracetam
Mech: ?
Met: EXCRETED KIDNEY
Side: sleepy