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32 Cards in this Set

  • Front
  • Back
How are the cunate and gracile tracts similar?
they carry information to the cortex about:
1. discriminatory touch
2. proprioception
3. vibration
How are the cuneate and gracile tract different?
cuneate tract carries information from the upper part of SC (above T12)

gracile carries information from below T12
True or false:

Cuneate and Gracile tracts decussate after they join together at the brain stem?
False

Cuneate and Gracile tracts join in the spinal cord

They do, however, decussate after the brainstem
Name the 3 main tracts of the lateral white column
1. Spinothalamic Tract (StT)
2. Spinocerebellar Tract (ScT) -focus on dorsal
3. Corticospinal Tract (CsT) -focus on lateral
What information does the StT carry?

Describe where the tract goes
Mainly pain and temperature
(also carries SIMPLE touch and pressure)

Starts from the dorsal root ganglia -> dorsal horn -> nucleus proprius -> decussate (in SC) ->axons form StT around ventral horn -> ascends and more axons are added on as it proceeds upwards -> brainstem (BS) -> thalamus -> cortex
What information does the ScT carry

Describe where the tract goes
Carries: unconscious proprioception for coordination of movement

Splits into dorsal and ventral
Neurons originate from the nucleus dorsalis (in the intermediate zone)
Ends in the cerebellum (without decussating)

Does NOT go to the CORTEX
What information does the CsT carry

Describe where the lateral tract goes
Unlike the other two, CsT is a descending tract and it controls voluntary movement

cerebral cortex (esp. precentral motor cortex) -> brainstem -> decussate -> SC -> at all levels, the axons terminate on motor neurons in the adjacent ventral horn
If there is a lesion that affects ScT and DCT, what would you expect?
You'd lose proprioception on the ipsilateral side (ScT and DCT) and tactile loss (DCT)

DCT = conscious proprioception
SCT= unconscious proprioception
Describe the patter of degeneration of motor and sensory neurones after a SC transection.
Sensory neurons degenerate above the transection

Motor neurons degenerate below the transection
Why is at transection of C1, C2 or C3 fatal?
You lose innervation of the diaphragm (phrenic nerve) and respiratory muscles
Explain what happens with a C4, C5 transection.
quadriplegia, lost of all sensation below level of lesion and loss of voluntary control of bowel and bladder
True or False

Lesions in the thoracic region causes paraplegia but no loss of voluntary control over bowel and bladder
False

There is loss of control over bowel and bladder
What is an upper motor neurone paralysis?

Describe 3 ways it can occur
UMNP : paralysis resulting from damage to the CsT (extensive voluntary paralysis)

1. stroke in the cerebral cortex
2. loss of blood supply to the tract
3. transection
What are the typical features of UMNP?

And give an explanation for why they occur
1. widespread voluntary paralysis
2. increase muscle tone in paralysed muscles
3. exaggerated tendon reflexes in paralysed muscles

Surviving nerve supply allows reflex activity and maintenance of muscle tone
True of false

a peripheral nerve lesion is a typical lower motor neuron lesion?
True
What does lower motor neurone paralysis refer to?
LMNP: loss of ventral horn cells or ventral roots or spinal nerves
What are the typical features of LMNP?

And give an explanation for why they occur
1. restricted area of voluntary paralysis

And affected muscles display:
2. no muscle tone
3. atropy
4. no tendon reflexes
What is spinal shock?
a period of 2-6 weeks of no spinal reflexes and flaccid muscle tone (despite type of lesion) following severe brain or SC injuries to CsT (UMNP)
What is the most frequent UMN lesion?
capsular stroke

vascular accident in the internal capsule
Do skilled movements return after a SC lesion involving CsT?
Very poor recovery for skilled movements (distal muscles)

Proximal muscles recover better

RULE: lesion in the forebrain =better movement recovery than lesion in the SC
True of False:

CsT is the ONLY tract that deals with skilled movements, particularly of the hands
True
What are the three types of spinal reflexes?
1. Flexor reflex
2. Stretch reflex
3. gamma reflex loop
Describe how the Flexor Reflex works
1. Painful/Tactile stimulus

2. spinal interneurone (dorsal horn)

3. alpha cells (ventral horn)

4. motor end plate in somatic muscle

5. movement
Describe how the Stretch Reflex works

Note: Stretch reflex is for adjustment in muscle tone
Ia sensory neurons supplies neuromuscular in tendionous insertion of muscle (parallel to axons of somatic muscles)

1. Slight stretch of muscle, stretches neuromuscular spindles

2. Ia stimulated

3. alpha motor cells get the signal (ventral horn)

4. Signals motor end plate in somatic muscles

5. Adjustment in muscle tone
Describe how the gamma reflex loop works

Note: this reflex is for

A. maintenance of posture, equilibrium and basic movements

B. maintain the sensitivity of neuromuscular spindles
Function A

1. Axons from BS (reticular formation) -> SC

2. synapse with gamma motor cells

3. gamma motor cells (ventral horn) innervate Ia sensory neurons ("trick" Ia neurons into activating without muscle stretch in the periphery)

4. alpha cells activated

5. Increase tone in muscles

Function B
When a muscle contracts, the tension is relieved on the neuromuscular spindles thus Ia neurones will be insensitive to stretch. Gamma cells regular this when they fire, as they will cause the neuromuscular spindles to contract, restoring tension and sensitivity at any given muscle length
What level of the vertebral column does the SC finish?
L2
Which region of the spinal cord do the nerves exit above their corresponding vertebrae?
Cervical area
True or False

C1 is the only nerve that does not have a dorsal root
True
True or False

The spinal cord is mostly supplied by end-artieres
True
What segments of the SC are particular prone to ischaemia?
T4-L1

end-arteries in SC
What arteries supply the SC?
Single anterior spinal artery and
Two posterior spinal arteries (in pia)

They're branches of the vertebral arteries (sometimes PICA)
Most significant radicular artery: Great radicular artery (of Adamkiewicz). What segments does it supply?
T9-L1