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16 Cards in this Set
- Front
- Back
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5 A's of Dementia
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Aphasia
Amnesia Agnosia Aphasia Abstract thought disturbance |
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DDx of dementia
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DEMENTIAS
neuro Degenerative disorders Endocrine Metabolic Exogenous Neoplasm Trauma Infection Affective d/o Stroke/Structural |
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Treatment for Lambert-Eaton-Myesthenic syndrome
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Guanidine hydrochloride
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Treament for Alzheimers dz
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Donepezil (anticholinesterase)
Vitamin E (tocopherol) slows cognitive decline |
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MCC cause of death in Alzheimers pts
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aspiritation pneumonia
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CT/MRI appearance of Huntington's disease
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Cerebral atrophy esp in caudate and putamen.
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Tx for Huntingtons
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none really
haloperidol for psychosis reserpine for unwanted movements |
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Drugs that can cause Parkinson's
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Carbon disulfide
manganese "designer drugs" |
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Parkinson's Tetrad
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1) Resting tremor
2) Rigidity 3) Bradykinesia 4) Postrual instability festinating gait can also be seen |
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Treatment for Parkinson's
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- Bromocriptine (DA agonist) = 1st line
- Levadopa/Carbidopa = mainstays o tx - Selegiline (MAO-B -) dec need of levadopa - COMT - : entacapone, inc availability of levadopa |
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Multiple Sclerosis Triad
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1) Scanning speech
2) Intranuclear ophthalmogplegia 3) nystagmus ***sx classically worsen with a warm shower*** |
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MRI findings of MS
CSF findings |
mult, asymmetric periventricular white matter lesions esp in corpus collosum-> "dawson's fingers"
active lestions enhance with dadolinium -------------------------------- mononuclear pleocytosis (<5cells/mg), inc IgG index or oligoclonal bands |
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Treamtent of MS
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steroids for acute exacerbations
ABC Avonex/Rebif \ Betaseron \ Copaxone |-- for relapsing/rem / mitting / Mitoxantrone for worsening relapsing/remitting type |
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Guillain Barre syndrome is associated with
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recent Camplobacter jejuni, viral infection or influenza vaccine
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5 A's of GBS
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Acute inflammatory demyelinating polyradiculopathy
Ascending paralysis Autonomic neuropathy Arrythmias Albuminicytologic dissociation ( CSF protien >55mg/dL c lil or no pleocytosis) |
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Treament of Guillan Barre syndrome
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Steroids and plasmaphoresis
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