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16 Cards in this Set

  • Front
  • Back
5 A's of Dementia
Aphasia
Amnesia
Agnosia
Aphasia
Abstract thought disturbance
DDx of dementia
DEMENTIAS

neuro Degenerative disorders
Endocrine
Metabolic
Exogenous
Neoplasm
Trauma
Infection
Affective d/o
Stroke/Structural
Treatment for Lambert-Eaton-Myesthenic syndrome
Guanidine hydrochloride
Treament for Alzheimers dz
Donepezil (anticholinesterase)

Vitamin E (tocopherol) slows cognitive decline
MCC cause of death in Alzheimers pts
aspiritation pneumonia
CT/MRI appearance of Huntington's disease
Cerebral atrophy esp in caudate and putamen.
Tx for Huntingtons
none really
haloperidol for psychosis
reserpine for unwanted movements
Drugs that can cause Parkinson's
Carbon disulfide
manganese
"designer drugs"
Parkinson's Tetrad
1) Resting tremor
2) Rigidity
3) Bradykinesia
4) Postrual instability

festinating gait can also be seen
Treatment for Parkinson's
- Bromocriptine (DA agonist) = 1st line
- Levadopa/Carbidopa = mainstays o tx
- Selegiline (MAO-B -) dec need of levadopa
- COMT - : entacapone, inc availability of levadopa
Multiple Sclerosis Triad
1) Scanning speech
2) Intranuclear ophthalmogplegia
3) nystagmus

***sx classically worsen with a warm shower***
MRI findings of MS

CSF findings
mult, asymmetric periventricular white matter lesions esp in corpus collosum-> "dawson's fingers"

active lestions enhance with dadolinium
--------------------------------

mononuclear pleocytosis (<5cells/mg), inc IgG index or oligoclonal bands
Treamtent of MS
steroids for acute exacerbations

ABC

Avonex/Rebif \
Betaseron \
Copaxone |-- for relapsing/rem
/ mitting
/

Mitoxantrone for worsening relapsing/remitting type
Guillain Barre syndrome is associated with
recent Camplobacter jejuni, viral infection or influenza vaccine
5 A's of GBS
Acute inflammatory demyelinating polyradiculopathy
Ascending paralysis
Autonomic neuropathy
Arrythmias
Albuminicytologic dissociation ( CSF protien >55mg/dL c lil or no pleocytosis)
Treament of Guillan Barre syndrome
Steroids and plasmaphoresis