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14 Cards in this Set

  • Front
  • Back
neural tube defect (dysraphism)
developmental defect (week 3 to 4 of gestation)
craniorachischisis
whole neural system NTDS
total dysraphism of brain is...
cranioschisis or anecephaly
spinal cord formation
notocord induces mesderm to form vertebrae...reciprocal induction exists b/w nervous system and vertebrae
spina bifida
defective development of caudal neuropore
spina bifida occulta
occult = hidden

no neural tissue involved

around L5-S1

in 2%

hard to find!
spina bifida cystica
spina bifida meningocele

spina bifida meningomyelocele

spina bifida myelocele
spina bifida with meningocele
cele = sac/cyst

sac contains menginges/CSF

intact nervous system
spina bifida with meningomyelocele
spinal cord and nerve roots are included in sac

more common than meningocele

many die from infections

neural deficits can occur
spina bifida with myelocele
most severe of spina bifida cystica

spinal cord completely open!

myelo = SPINAL CORD
hydrocephalus
associated with myelomeningocele

abnormality called Chiari malformation
Chiari malformation
medullary portion of brainstem and portions of cerebellum herniate through foramen magnum

disrupts normal drainage of CSF from 4th ventricle into subarachnoid space
encephalocele
skin covered NTD of brain.

tissue protrudes through the skull

large ones can affect neurologic function/survival
anencephaly/meroanencephaly
most of brain is exposed/extruding

abnormal forebrain development and defect in calvaria

failure of rostral neuropore to close

1/1000 birts

4x in females

extrauterine life is impossible.