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49 Cards in this Set

  • Front
  • Back

Superior cerebellar peduncle

cerebellar output



where tract crosses

middle and inferior cerebellar peduncle

cerebellar input

cuneocerebellar tract

arm propreoception



arm interneurons



inferior cerebellar peduncle


dorsal spinocerebellar tract

leg propreoception



leg interneurons



inferior cerebellar peduncle

middle peduncle receives info from...

cerebral cortex

purkinje cells

where ALL cerebellar input goes

inputs to cerebellum

-cerebral cortex


-inferior olive


-spinal cord


-vestibular nucleus

lateral hemisphere

deep nuclei= dentate (projects to red N.)



plans output



target= superior peduncle

intermediate hemisphere

deep nuclei= interposed



motor manipulation (planning)



target= superior peduncle

vermis

deep nuclei= fastigial + vestibular



head/core/balance



target= superior + inferior peduncle


vermis + flocculonodular lobe

deep nuclei= vestibular



target= MLF



eye movement


how many times does the cerebellar output cross?

twice


cerebellar gait deficit

ataxia

magnocellular red nucleus

crosses at ventral tegmental decussation



makes movement

parvocellular red nucleus

plans movement

botzinger complex

does breathing



in medulla

basal ganglia

caudate nucleus


putamen


globus pallidus


subthalamic nucleus


substantia nigra - main motor output

striatum

putamen + caudate nucleus



receives input



part of basal ganglia

parkinson's disease
dopamine degeneration in the substantia nigra



hard to create movement



huntington's disease
contralateral lesions in the subthalamic nucleus
dopamine
in substantia nigra pars compacta



released to striatum




direct pathway = excitatory


indirect pathway = inhibitory

basal ganglia indirect pathway
cortex (E)->caudate(I)->GPi(I)->SubthalN(E)->GP/SN(I)->VA/VL of thalamus(E)->cortical motor area



movement inhibited



basal ganglia direct pathway
cortex(E)->caudate(I)->GP/SN(I)->Thalamus(E)



movement excited




"inhibition of inhibition"

Basal ganglia neurotransmitters
Gaba=inhibitory

Glutamate=excitatory


dopamine=(+/-)

basal ganglia neurons
always a little bit active



release only 1 type of neurotransmitter




always firing APs

occulomotor channel
frontal eye fields>VA/MD of thal



basal nuclei input=caudate body


basal nuclei output=GPinternal/SNp

limbic channel
anterior cingulate>MD/VA of thal



basal nuclei input=nucleus accumbens


basal nuclei output=GPinteral/SNp

motor channel
premotor&primary motor cortex>VL/VA of thal



basal nuclei input=putamen


basal nuclei output=GPinternal/SNp

prefrontal channel
prefrontal cortex>VA/MD of thal



basal nuclei input=caudate head


basal nuclei output=GPinternal/SNp

where does dopamine come from?
cortex from substantia nigra pars compacta
where does dopamine target?
striatum
output nuclei of the cerebellum
globus pallidus internal and substantia nigra pars compacta
hemiballismus
contralateral lesion of the sub thal nucleus



arms and legs flail




destruction of indirect pathway

huntington's
striatum degeneration



indirect dies quicker = more movement

nucleus accumbens
receives dopamine from the ventral tegmentum
limbic system
"reward feeling"



projects to nucleus accumbens when something good happens to you





hypothalamus
master hormone regulator



regulates period, feelings, hormone regulation

pituitary
hormone release regulation



receives info from hypothalamus




skin + nervous system

Wernicke's area
speech cognition
Broca's speech area
speech production
anterior pituitary
gland



needs stimulus- releasing or inhibiting factor from hypothalamus




goes to bloodstream

posterior pituitary
synapses into blood stream and releases neurotransmitters/hormones



oxytocin and vasopressin




cell bodies located in PVN and SON





median eminance
infundibulum and top capillary beds
limbic system
one lobe for each side-wraps around lateral ventricles
cingulate gyrus - emotion
amygdala - memory (in front of hippocampus)
hippocampus - sensory input
Suprachaismatic nucleus of the hypothalamus

(SCN)

receives input from the retina



lets hypothalamus know if day or night



regulates melatonin release from pineal gland


hippocampal circuit
Entorhinal Cortex-dentate-CA3-CA1-subiculum
CA
part of hippocampus



"cornus ammons proper horn"

association cortices
receive info from other cortices and process/decide body's action

-entorhinal


-parahippocampal


-perirhinal

hippocampus
converts short-term to long-term
folds over on itself during development
well connected to association cortices