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7 Cards in this Set

  • Front
  • Back
Alpha-latrotoxin
Black Widow toxin
tetramer forms pore
Ca enters terminal
neurotransmitters released constantly - seizures
Scorpian Alpha toxin
slows inactivation gate of voltage gated sodium channels
Scorpian Beta Toxin
slows activation gate of voltage gate sodium channels.
Need more depolarization to open gate.
Scorpian charybdotoxin
Blocks voltage gated potassium channels
Scyllatoxins
blocks Ca activated voltage gated K channels
apamin
block Ca activated gated small conductance potassium channels - SK
blocks hyperpolarization - unable to prevent back propagation
a-bungarotoxin
blocks nmj acetylcholine ionotropic receptors
does not block autonomic acetylcholine receptors - different receptor