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5 Cards in this Set
- Front
- Back
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what percent of people w. polio will have sx?
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1%
but they can still transmit the dz |
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how is polio mostly spread?
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Asymptomatic infection in 90-95%
(primary source of epidemic spread). fecal oral the only reservoir is man |
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paralytic poliomyelitis only occurs in 1% of ppl, what are the sx of this? how does it kill you
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loss of fnction in limbs due to neuronal destruction
respiratory paralysis-->death |
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what are the 2 tx for polio? which is used to eliminate the virus from the environment
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Salk (killed)
Sabin (live, attenuated) vaccines --sabin prevents fecal-oral spread of wild type-->eliminates from environment Major disadvantage of sabin: but may lead to minor/major disease (including VAPP – vaccine associated paralytic poliomyelitis). |
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3 stratigies for polio tx
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Multiple doses of Sabin-
Countries with continuing disease prevalence: “National Immunization Days” Two doses Salk, followed by 2 doses Sabin Countries w/o polio, but with continued environmental presence of wild-type virus. Four doses Salk Countries where viruses have been eradicated. |
