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46 Cards in this Set

  • Front
  • Back
1st line drug for tonic seizures
phenytoin
carbamazepine
valproic acid
1st line drug for simple partial seizures
carbamazepine
1st line drug for partial complex
carbamazepine
DOC for absence seizures
ethosuximide
DOC for status epilepticus
benzos
MOA for phenytoin
increase Na+ channel inactivation
MOA for carbamazepine
increase Na+ channel inactivation
First line for pregnant women and children with seizures
phenobarbitol
Facilitate GABA-a action by increase duration of Cl- chanel opening
Barbiturates
Facilitate GABA-a action by increase frequency of Cl- chanel opening
benzos
benzos vs barbs...MOA
barbs- duration barbiDURATIONates)
benzos- frequency (frenzodiazepines)
agranulocytosis and aplastic anemia
carbamazepine
gingival hyperplasia, hirsutism, fetal hydantoin syndrome and megaloblastic anemia
phenytoin
rare by fatal hepatotox and neural tube defects
valproic acid
kidney stones
topiramate
act via the BZ1 receptor subtype and is used to treat insomnia... lower dependence risk than benzos
zolpidem
act via the MT1 and MT2 receptor
ramelteon.... gets you to sleep, doesnt help you stay there
inhibits stage 3 and rem sleep
benzos
anesthetic that cuases hepatotoxicity
halothane
anesthetic that cuases epileptic AEs
enflurane
anesthetic that is used for brain surgery bc in decreases BF to brain
isoflurane
anesthetic that causes nephrotoxicity
methoxyflurane
anesthetic that is proconvulsant
enflurane

enflurane = epilepsy
barbiturate IV anesthetic that is high potency and high lipid soluble with rapid entry into brain
thipental... good for induction
MC drug used for endoscopy
midazolam
bad dreams, increases cerebral bloo flow, awake/but not
ketamine
an opiate that does nto induce histimine release like morphine does
fentanyl
can lead to pancreatitis with chonic use
propofol (bc it increases TB content)
treatment for malignant hyperthermia
dantrolene
drugs used to treat parkinsonism/ dz
bromocriptine (+ dopamine receptors)
amantadine (increase dopamine levels)
selegiline (prevents dopamine breakdown)
benztropine (decreases tremor)
selectively inhibits MAO-B, increasing the availability for dopamine
selegiline
Alz drugs
memantine (NMDA receptor antagonist)
donepizil, galantamine, rivastigmine (AChE [-])
three AChE inhibitors used in treatment of Alz dz
donepizil, galantamine and rivastigmine
drugs used to treat huntington's dz

(characterized by increased dopamine and decreased GABA + ACh
reserpine/ tetrabenazine (amine depleting)
haloperidol (dopamine receptor [-])
5HT1b/1d agonist
sumatriptan

migraines... do not give with CAD or prinzmetal's angina
list the drugs used to treat glaucoma
alpha (+)
Beta(-)
diuretics
cholinomimetics
prostaglandins
which alpha agonist is used to treat glaucoma
epinephrine and brimonidine

decreases aquaeus humor synthesis due to Vc
which beta blocker is used to treat glaucoma
timolol, betaxolol and carteolol

increases aqueous humor secretion
which diuretics are used to treat glaucoma
manitol and acetazolamide
which cholinomimetic is used to treat glaucoma
pilocarbine (direct) and physostigmine (indirect)
what is the MOA of opiod analgesics
opens K+ channels, closes Ca2+ channels and decreases synaptic transmission

also, inhibits ACh, NE, 5HT, glutamate and substance P release
opiod used for pain and cough
dextromethorphan
opiod used for diarrhea
loperimide and diphenexylate)
opiod used for heroin addicts
methadone
anti-opiod
naloxone and naltrexone
opiods cause _____ pupils
pinpoin pupils