Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
46 Cards in this Set
- Front
- Back
1st line drug for tonic seizures
|
phenytoin
carbamazepine valproic acid |
|
1st line drug for simple partial seizures
|
carbamazepine
|
|
1st line drug for partial complex
|
carbamazepine
|
|
DOC for absence seizures
|
ethosuximide
|
|
DOC for status epilepticus
|
benzos
|
|
MOA for phenytoin
|
increase Na+ channel inactivation
|
|
MOA for carbamazepine
|
increase Na+ channel inactivation
|
|
First line for pregnant women and children with seizures
|
phenobarbitol
|
|
Facilitate GABA-a action by increase duration of Cl- chanel opening
|
Barbiturates
|
|
Facilitate GABA-a action by increase frequency of Cl- chanel opening
|
benzos
|
|
benzos vs barbs...MOA
|
barbs- duration barbiDURATIONates)
benzos- frequency (frenzodiazepines) |
|
agranulocytosis and aplastic anemia
|
carbamazepine
|
|
gingival hyperplasia, hirsutism, fetal hydantoin syndrome and megaloblastic anemia
|
phenytoin
|
|
rare by fatal hepatotox and neural tube defects
|
valproic acid
|
|
kidney stones
|
topiramate
|
|
act via the BZ1 receptor subtype and is used to treat insomnia... lower dependence risk than benzos
|
zolpidem
|
|
act via the MT1 and MT2 receptor
|
ramelteon.... gets you to sleep, doesnt help you stay there
|
|
inhibits stage 3 and rem sleep
|
benzos
|
|
anesthetic that cuases hepatotoxicity
|
halothane
|
|
anesthetic that cuases epileptic AEs
|
enflurane
|
|
anesthetic that is used for brain surgery bc in decreases BF to brain
|
isoflurane
|
|
anesthetic that causes nephrotoxicity
|
methoxyflurane
|
|
anesthetic that is proconvulsant
|
enflurane
enflurane = epilepsy |
|
barbiturate IV anesthetic that is high potency and high lipid soluble with rapid entry into brain
|
thipental... good for induction
|
|
MC drug used for endoscopy
|
midazolam
|
|
bad dreams, increases cerebral bloo flow, awake/but not
|
ketamine
|
|
an opiate that does nto induce histimine release like morphine does
|
fentanyl
|
|
can lead to pancreatitis with chonic use
|
propofol (bc it increases TB content)
|
|
treatment for malignant hyperthermia
|
dantrolene
|
|
drugs used to treat parkinsonism/ dz
|
bromocriptine (+ dopamine receptors)
amantadine (increase dopamine levels) selegiline (prevents dopamine breakdown) benztropine (decreases tremor) |
|
selectively inhibits MAO-B, increasing the availability for dopamine
|
selegiline
|
|
Alz drugs
|
memantine (NMDA receptor antagonist)
donepizil, galantamine, rivastigmine (AChE [-]) |
|
three AChE inhibitors used in treatment of Alz dz
|
donepizil, galantamine and rivastigmine
|
|
drugs used to treat huntington's dz
(characterized by increased dopamine and decreased GABA + ACh |
reserpine/ tetrabenazine (amine depleting)
haloperidol (dopamine receptor [-]) |
|
5HT1b/1d agonist
|
sumatriptan
migraines... do not give with CAD or prinzmetal's angina |
|
list the drugs used to treat glaucoma
|
alpha (+)
Beta(-) diuretics cholinomimetics prostaglandins |
|
which alpha agonist is used to treat glaucoma
|
epinephrine and brimonidine
decreases aquaeus humor synthesis due to Vc |
|
which beta blocker is used to treat glaucoma
|
timolol, betaxolol and carteolol
increases aqueous humor secretion |
|
which diuretics are used to treat glaucoma
|
manitol and acetazolamide
|
|
which cholinomimetic is used to treat glaucoma
|
pilocarbine (direct) and physostigmine (indirect)
|
|
what is the MOA of opiod analgesics
|
opens K+ channels, closes Ca2+ channels and decreases synaptic transmission
also, inhibits ACh, NE, 5HT, glutamate and substance P release |
|
opiod used for pain and cough
|
dextromethorphan
|
|
opiod used for diarrhea
|
loperimide and diphenexylate)
|
|
opiod used for heroin addicts
|
methadone
|
|
anti-opiod
|
naloxone and naltrexone
|
|
opiods cause _____ pupils
|
pinpoin pupils
|