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18 Cards in this Set
- Front
- Back
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Paraventricular and supraoptic nuclei make what molecules?
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Vasopressin + oxytocin
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Infundibulum defect
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= Adenohypohyseal relesaing peptide deficiency = LHRH, GHRH, TRH, CRH
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What is the disease where a defect in migration of the cells that produces LHRH does not migrate from the cribiform plate to the hypothalamus called?
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Kallmans syndrome
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What is the defect caused by kallmans syndrome?
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Anosmia (cant smell) + gonad dysgenesis (sterility)
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What neurons detect ↑ body temp and initiate heat loss (aka cooling)
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Anterior hypothalamus
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What happens in a lesion of the anterior hypothalamus?
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Hyperthermia b/c lack of cutaneous vasodilation + sweating -> ↑ body temp and die
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What neurons are sensitive to ↓ body temp and initiate heat gain?
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Posterior hypothalamus
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What happens in a lesion of the posterior hypothalamus?
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Poikilothermia (same body temp as environment) - b/c of lack of cutaneous vasoconstriction and shivering (cant ↑ body temp)
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What nucleus in the hypothalamus is associated with fasting?
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Paraventricular and ventromedial nuclei
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What happens when there is a lesion to the paraventricular and ventromedial nuclei of the hypothalamus?
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Lesion the fasting zones thus ↑ appetite -> obesity
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What nucleus in the hypothalamus is associated with hunger (appetite)?
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Lateral hypothalmic zone
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What happens when there is a lesion to the lateral hypothalmic zone?
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Lesion of the appetite zone -> ↓ food and drink intake -> loose weight
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What nucleus receives input from the retina and is responsible for 24 hr circadian rhythm?
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Suprachiasmatic nucleus
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What happens with a lesion to the posterior hypothalamus?
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Lesion to the awake zone = hypersomnia (lots of sleep)
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What happens when there is damage to the ventromedial nuclei bilaterally?
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Lesion bilaterally to ventromedial = extreme aggressiveness - attack repeatedly w/o provocation
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What is the function of anterior hypothalamus
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Parasympathetic events
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What is the function of posterior hypothalamus on regulation of ventromedial nuclei?
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Regulatory effect on posterior hypothalamus -> sympathetic activation
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Pathway for sexual regulation
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Arcuate nucleus + tuberal nuclei (makes releasing hormones)-> Hypothalamus (infundibulum) -> LHRH -> anterior Pituitary (hypophysis) -> LH, FSH -> fenestrated capilaries -> blood circulation -> ostrogen, progesteron (testis, ovarium)
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