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43 Cards in this Set

  • Front
  • Back
Part of Neuron

integration of analog signals (synaptic potentials) to produce digital signals (action potentials)
Axon hillock/ initial segment
Part of Neuron

reception of synapses from other neurons
dendrites, dendritic spines, and cell bodies most commonly

axon terminals less commonly
Part of Neuron

Transmission of information to other neurons
axon terminal
what keeps ions inside and outside from mixing freely
plasma membrane
what two types of proteins exist to move ions from inside to outside
channels and pumps
The ion K is positive. There is a larger concentration of it inside of the cell than outside of it. Why is the inside of the cell more negative than the outside
leak channels allow K to leave the cytoplasm which leaves behind a negative charge. The charge builds up until is it equal and opposite to the force of the concentration difference.
what happens at threshold that turns a synaptic depolarization into an action potential
voltage gated Na channels open
the part of an action potential where the permeability of Na is zero
absolute refractory period because a neuron can't generate another action potential at that time
What two types of resistance determine the speed of condution
membrane resistance and internal resistance
Which of these types of resistance is affected by myelin? What does myelin do to that resistance?
myelin increases membrane resistance
what types of supporting cells in the central and peripheral nervous system produce myelin
CNS-oligodendrocytes
PNS-schwann cells
Function of organelles

Nissel bodies
protein translation
Function of organelles

Golgi Complex
The function is to modify, sort, and package proteins and other materials from the endoplasmic reticulum for storage in the cell of secreation outside the cell.
Function of organelles

Microtubules
esponsible for movement of mitochondria, lipids, synaptic vesicles, proteins, and other cell parts (i.e. organelles) to and from a neuron's cell body, through the cytoplasm of its axon (the axoplasm)
Function of organelles

Ribosomes
site of protein synthesis
Function of organelles

Mitochondria
used to synthesize adenosine triphosphate (ATP). The ATP molecule stores energy within its chemical bonds, releasing this energy to fuel cellular processes as needed.
Function of Organelles

Nucleus
It contains the nucleolus and chromosomes, necessary for the coded production of proteins within the cell. The nucleolus of the nucleus produces ribosomes.
If all you had available was the means to look at proteins at a synapse which proteins would you look at to determine if the synapse was electrical or chemical
chemical-synaptic vesicle or ligand-gated receptor

electrical-connexins
If all you had was too electrodes one record from dendrite and one to stimulate axon. what would tell you that the synapse was chemical or electrical?
look for delay between stimulation and recording
in depolarization channels for which ion are opened by the release of a neurotransmitter?
Na+
Name three things that indicate GABA has been released by the axon
presence, release, effect pharmacological mimicry and termination
stimulation in an axon produces rapid hyperpolarization in one dendrite. what type of receptor is present at this synapse
ionotropic
an axon is stimulated but you observe a slower more prolonged effect in the second dendrite. What receptor is present at this synapse
metabotropic
When the neural tube fails to close
spina bifida
what would cause a growth cone to become lost?
an actin antagonist

cytochalasin
In a growth cone what propels the fillopodia forward?
actin fillaments
In the stretch reflex what is the role of the motor neuron?
It sends inhibitory signal to the antagonist muscle
what instructs ectoderm to become skin?
BMP

Bone morphogenic protein
What inhibits the effect of BMP?
noggin, chordin, falistatin
What can aid in prevention of programmed cell death?
Neurotrophins
Name the neurotropins and tracks?
NGF trk A (pain and temp)

BDNF trk B (touch receptors)

NT-3 trk C

NT-4 trk B
Several touch receptors that end on the same motor neuron fire action potentials at the same time and drive the motor neuron to become active.
spatial summation
One stretch receptor fires action potentials at a very high rate- this, too, drives the motor neuron to become active.
Temporal summation
A stretch receptor and one in the patellar tendon are both active and the motor neuron fails to generate an action potential
autogenic inhibition

could be spatial summation because inhibitory+excitatory= inhibitory
Radial glia serve to major functions in the development of neurons. What are those two functions?
highways along which neurons migrate radially to their destinations and source of neural progenitor cells
What two areas are responsible for speech and how do they differ?
Broca's area-motor speech impairment


Wernicke's area-speech comprehensoin
Growth cones need to cross the midline for escape reflexes requiring contra lateral control. How do growth cone maneuver past the alluring midline?
1. Midline has neutrin

2. DCC attracted to neutrin

3. Slit found at midline repels DCC

4. Robo receptor attracted to slit but wants to know if there is more past midline

5. Passes midline
What repels axons and attracts dendrites?
Sema 3A
what cell layer becomes bone, muscle and blood cells
Mesoderm
What cell layer becomes gut liver and lungs
Endoderm
What cell layer becomes skin or neurons
ectoderm
pituitary gland
rathke's pouch
PNS made from what?
Neural crest