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17 Cards in this Set
- Front
- Back
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Dementia is a chr, progres, global decline in which cognitive ares? (5 A's)
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Aphasia
Amnesia Agnosia Apraxia Abstract thought disturb (executive func prob) |
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what is most common cz of dementia
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alzheimer
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what is ddx of dementia?
(DEMENTIA) |
neuroDEGENRATIVE dz
Endocrine Metabolic Exogenous Neoplasm Trauma Infection Affective d/o Stroke/Structural |
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What is the most impt rf for alzheimer
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age
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other rf for dementia
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FAMILY HX
DOWN SYNDROME (>35) female low education level |
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Path seen in alzheimer
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NEUROFIBRILLARY TANGLES
NEURITIC PLAQUES W/ AMYLOID DEPOSITS amyloid angiopathy neuronal loss |
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what is usu the 1st sign of Alz?
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amnesia
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DDx of Alz
(some cz of dementia) |
multi-infarct dementia
Pick's pseudodementia (depression) NPH subdural hemorrhage intracranial abscess tumor |
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T or F
Alz is a dx of exclusion |
T
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Why is Alz a dx of exclusion? (how is is definitely dx)
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dx only at autopsy
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t or f
neuropsych testing can disting b/w dementia and depression |
T
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what labs would you perform in dx alz/dementia?
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cbc, esr, lytes, tsh, serum b12
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tx of alzheimer's--first line
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cholinesterase inhibitors
(donepezil, rivastigmine, galantamine) |
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what vit _may_ slow decline
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vit E
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T or F
selegiline, other anti-ox, anti-inflam, estrog have not shown equivocally to afffect dz course |
T
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#yrs survival frm onset of sx
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5-10
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death d/t? (secondary)
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aspiration pneumonia
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