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31 Cards in this Set
- Front
- Back
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What toxicity are you worried about with Halothane and due to what free radical?
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Hepatic; chlorotrifluorethyl
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With what drugs is malignant hyperthermia a concern?
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Succinylcholine, sevoflurane and desflurane
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What is the tx for malignant hyperthermia?
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Dantrolene
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The lower the MAC...
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The more potent the agent
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The more soluble the drug in the blood...
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Slower the rate of induction
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Alterating the ventilation rate does what to the induction of agents?
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> the speed of induction of agents with greater solubility in the blood
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Increased cardiac output does what to induction?
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Slows
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Decreased blood flow does what to induction?
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Speeds it up
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What is the only effect of Halothane?
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produces sleep only
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What needs to be added to halothane?
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NO for analgesia and Succinylcholine for muscle relaxation
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What drug should NOT be used with catecholamines?
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Halothane
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What are some advantages and uses of Halothane?
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Uterine relaxation and reasonable induction and recovery
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What drug should be avoided in patients with epilepsy?
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Enflurane
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What is an advantage of Enflurane?
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Good skeletal muscle relaxation and med rate of induction
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What drug has a pungent, irritating odor and can cause progressive respiratory depression and hypotension?
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Isoflurane
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What drug can be used with catecholamines?
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Isoflurane
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What are some advantages of Isoflurane?
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No cardiac depression and good skeletal muscle relaxation
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What drug is pungent and especially irritating to the airway?
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Desflurane
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What is replacing Isoflurane due to better control?
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Desflurane
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What drug reacts with CO2 absorbants to form a nephrotoxic metabolite that may release flouride ions causing renal damage?
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Sevoflurane
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What drug is very rapid and smooth induction and rapid recovery and can be used via mask?
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Sevoflurane
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What is a disadvantage of NO?
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produces only analgesia
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What drug must be avoided in conditions where there are air pockets in the area of surgery?
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NO
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Which drug is contraindicated in patients with acute intermediate porphyria?
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Thiopental
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What drug has an especially good recovery (upbeat mood)?
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Propofol
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Where is more hypotenstion produced and due to what? (Propofol or Thiopental?
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Propofol due to histamine release causing vasodilation
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What drug produces a dissociate anesthesia?
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Ketamine
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How does Ketamine work?
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Blocks the effects of glutamic acid at NMDA receptors
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In which drug are respiration and protective reflexes well maintained?
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Ketamine
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What drug may be particularily useful in the ER, dressing changes, radiological procedures in kids?
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Ketamine
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Which drug would show high incidence of myoclonia (arm flexing) during injection?
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Etomidate
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