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45 Cards in this Set

  • Front
  • Back
What are the three mechanisms of an ischemic stroke?
Thrombosis
Emboli
Hypoperfusion
Name four anastomotic channels in the anterior circulation of the brain.
Posterior and anterior communicating arteries
Leptomeningeal connections
Ophthalmic artery to ext carotid artery anastomoses.
An older man with a history of diabetes and hypertension comes in with sudden onset focal disability.
Ischemic stroke.
What underlying disease does Amaurosis Fugax indicate?
Extracranial carotid artery disease with retinol emboli.
Occlusion of what can present as amaurosis fugax, and MCA stroke, or a combined MCA/ACA stroke?
Internal carotid artery stenosis/occlusion
Broca's aphasia is supplied by an anterior branch of the MCA and typically associated with what finding?
Right hemiplegia
Wernicke's aphasia is supplied by a posterior branch of the MCA and is associated with what finding?
Right homonymous hemianopsia
Syndrome associated with agraphia, acalculia, finger agnosia, and left-right confusion.
Gerstmann's Syndrome
Anosognosia (denial of illness) and asomatosognosia (denial of body parts) are associated with a stroke located where?
Non-dominant hemisphere, usually right, localized to the parietal lobe.
Wernicke's aphasia, Broca's aphasia, Gerstmann's syndrome, and syndromes involving denial of illness are associated with strokes in which artery?
MCA
In an ACA stroke, the hemiparesis and sensory loss is due to an infarct in which area?
Paracentral lobule
Urinary incontinence is typically seen with strokes involving which artery?
ACA
Sudden onset pure motor weakness in face, arm, and leg
Urinary incontinence
Abulia
Stroke of the ACA involving the artery of Heubner
Sudden onset leg weakness, sensory loss, problems with continence, frontal lobe release signs, lack of will/animation
Stroke of the ACA, probably bilateral due to abulia and release signs
Sudden onset ne-sided weakness and sensory loss, mostly of the leg, incontinence. What kind of stroke?
ACA
Posterior limb of the internal capsule is supplied by which artery?
Anterior choroidal artery
Posterior limb of the internal capsule, internal segment of the globus pallidus, optic tract, and the choroid plexus in the temporal horn of the lateral ventricle are supplied by what artery?
Anterior choroidal artery
Comtralateral hemiplegia and hemisensory loss
contralateral homonymous hemianopsia with a spared beaklike zone horizontally
Anterior choroidal artery
Crossed stroke findings point to a stroke involving which artery?
PCA
Syndrome from stroke involvement of the posterior inferior cerebellar artery
Lateral medullary syndrome
Stroke resulting in medial medullary syndrome involves which artery?
Anterior spinal artery.
Contralateral hemiplegia with sparing of face
Contralateral loss of vib and prop
Ipsilateral tongue weakness

What syndrome?
Medial medullary
Contralateral hemiplegia with sparing of face
Contralateral loss of vib and prop
Ipsilateral tongue weakness

What arteries involved in stroke?
Anterior spinal artery distribution of the Vertebral arteries
Lateral medullary syndrome--artery involved?
Posterior inferior cerebellar artery (PICA)
Contralateral decreased pain and temp in arm and leg
Ipsilateral decreased pain and temp in face

Can also have miosis, ptosis, anhydrosis, limb ataxia, hiccips, nystagmus.
Lateral medullary syndrome
What area is affected in lat medullary syndrome to give hoarseness, dysphagia, hiccups, decreased gag reflex?
Nucleus ambiguous
What area is affected by lat medullary syndrome to give nystagmus, vertigo, nausea, and vomiting?
Vestibular nuclei
What area is involved in lat medullary syndrome to give decreased ipsilateral pain and temp to the face?
spinal trigeminal nucleus (V)
Testing of the CSF hows increased Ig, oligoclonal bands which aren't found in blood, and increased MBP
Multiple schlerosis
Category of demyelinating disease which follows an infection and immune response, but shows no infective agent at time of demyelination
Perivenous Encephalomyelitis
Mild version of Perivenous Encephalomyelitis, usually preceded by viral infections such as measles, mumps, chicken pox, rubella, and influenza
Acute disseminated encephalomyelitis (ADEM)
More severe version of Perivenous Encephalomyelitis, usually preceded by a systemic viral infection or respiratory infection such as measles or atypical pneumonia
Acute hemorrhagive leukoencephalitis (AHLE)
Demyelinating disease targeting oligodendroglial cells, caused by a slow viral infection in an immunocompromised patient
Progressive Multifocal Leukoencephalopathy (PML)
Progressive Multifocal Leukoencephalopathy can be caused by what three polyomaviruses?
JC
BK
SV40
This demyelinating disease whos large oligodendroglial nuclei with viral inclusions, foamy macrophages, and atypical astrocytes
Progressive Multifocal Leukoencephalopathy (PML)
This leukodystrophy shows PAS+ and LFB+ macrophages showing metechromasia with cresyl violet staining
Metachromatic Leukodystrophy
This leukodystrophy shows progressive motor disability in childhood
Metachromatic Leukodystrophy
This leukodystrophy has an aryl sulfatase A deficiency and is a lysosomal disorder
Metachromatic Leukodystrophy
Leukodystrophy that shows tuffstein or zebra-like inclusions in white matter
Metachromatic Leukodystrophy
Leukodystrophy shows multinucleated globoid PAS + macophages in white matter
Globoid Dystrophy (GLD)/Krabbes
Leukodystrophy has galactocerebrosidase beta galactosidase deficiency and lysosomal disorder
Globoid Dystrophy (GLD)/Krabbes
Leukodystrophy shows developmental failure, tonic spasms, gait disorder, and spasticity
Globoid Dystrophy (GLD)/Krabbes
Leukodystrophy has storage of very long fatty acid chains and is perozisomal X-linked
Adrenal leukodystrophy (ALD)
Leukodystrophy that causes diffuse demyelination of mainly the posterior portion of the cerebellum
Adrenal Leukodystrophy (ALD)
Leukodystrophy that causes failure to thrive, seizures, and retinal degeneration in children
Adrenal leukodystrophy