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42 Cards in this Set
- Front
- Back
Which AA are modified by the GA
|
asparagine
serine threonine |
|
what other abnormalities are associated with arnold chiari?
|
hydrocephaly
syringomyelia thoracolumbar meningocele |
|
mesocortical pathway
|
ventral tegmentum
to cortex |
|
mesolimbic pathway
|
ventral tegmentum
to limbic system |
|
nigrostriatal pathway
|
substantial nigra
to striatum (caudate + putamen) |
|
tuberoinfundibular pathway
|
arcuate nucleus
to pituitary |
|
blockage of mesocortical pathway
|
increases negative psychosis symptoms
|
|
blockage of mesolimbic pathway
|
relieves psychosis
|
|
blockage of nigrostriatal pathway
|
increases parkinsons
|
|
blockage of tuberoinfundibular pathway
|
increases prolactin secretion
|
|
look like fried egg
|
oligodendroglia
|
|
form multinucleated giant cells in CNS of HIV px
|
microglia
|
|
myelinates CNS
|
oligodendroglia
|
|
myelinates PNS
|
schwann
|
|
a/w guillain barre
|
schwann
|
|
a/w MS
|
oligodendroglia
|
|
macrophages of CNS
|
microglia
|
|
form BBB
|
astrocyte
|
|
disease a/w decrease ACh
|
huntingtons
alzheimer |
|
disease a/w decreased GABA
|
huntingtons
anxiety |
|
disease a/w decreased NE
|
depression
anxiety/mania |
|
what makes up the reticular activating system
|
reticular formation (NE)
locus ceruleus (NE) raphe nucleus (5HT) |
|
what is a nissl substance
|
RER found on neurons
-cell body -dendrites loss = irreversible damage |
|
why are neurons sensitive to ischemia
|
do not store glycogen
|
|
markers for astrocytes
|
GFAP
glutamine synthetase monoclonal Ab A2B5 |
|
fried egg appearance on H/E
|
oligodendrocytoma
koilocyte (HPV) seminoma/dysgerminoma |
|
location of synthesis
NE |
locus ceruleus
reticular formation solitary tract |
|
location of synthesis
DA |
ventral tegmentum
substantia nigra |
|
location of synthesis
5HT |
raphe nucleus
|
|
location of synthesis
ACh |
basal nucleus of meynert
|
|
location of synthesis
GABA |
nucleus accumbens
|
|
what crosses BBB
|
glucose and AA
-slowly -carrier mediated nonpolar/lipid soluble -cross rapidly -diffuse |
|
what happens after infarction of BBB
|
destruction of tight junctions
vasogenic edema |
|
areas of brain that are fenestrated
|
area postrema
-vomiting after chemo OVLT -osmotic sensing neurohypophysis -ADH -oxytocin |
|
a/w increased AFP
|
anterior abdominal wall defect
neural tube defect |
|
development of telencephalon
|
cerebral hemisphere
basal ganglia hippocampus/amygdala lateral ventrical |
|
development of diencephalon
|
thalami
optic nerve/tract 3rd ventricle |
|
development of mesencephalon
|
midbrain
aqueduct |
|
development of
metencephalon |
pons
cerebellum 4th ventricle |
|
development of myelencephalon
|
medulla
4th ventricle |
|
dandy walker
|
absent cerebellar vermis
enlargement of the 4th ventricle lack of coordination and jerky eye movement may result from riboflavin inhibitors (INH) |
|
arnold chiari
|
cerebellar tonsillar herniation
aqueduct stenosis |