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82 Cards in this Set
- Front
- Back
Two subdivisions of the Nervous System
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Central nervous system (CNS)
Peripheral nervous system (PNS) |
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Central nervous system (CNS)
consists of |
brain and spinal cord
|
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Peripheral nervous system (PNS) consists of
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cranial nerves, spinal nerves, and ganglia
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CNS and PNS perform three general functions:
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1. Collecting Information
2. Processing and evaluating information 3. Responding to information |
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Two functional divisions of the NS
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Sensory NS
Motor NS |
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SNS Subdivided into two systems:
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1. Somatic sensory – touch, pain, pressure, vibration and proprioception
2. Autonomic sensory – impulses from viscera Motor Nervous |
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Somatic sensory
(Sensory NS) |
touch, pain, pressure, vibration and proprioception
|
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Visceral sensory
(Sensory NS) |
impulses from viscera
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Sensory NS(afferent)--sensory info from_____ receptors to_____ .
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PNS, CNS
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Motor NS(efferent)--sends impulses from _____ to _____ .
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CNS, effectors
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Somatic motor (voluntary)
(Motor NS) |
causes contraction of skeletal muscles
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Autonomic motor (involuntary)
(Motor NS) |
regulates smooth and cardiac muscle and glands
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Two distinct types of cells w/in NS:
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Neurons
Glial cells |
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electrically excitable cells
o initiate, transmit and receive nerve impulses |
Neurons
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non-excitable cells
o support and protect neurons |
Glial cells
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Cell that is the structural and functional unit of NS
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Neurons (nerve cells)
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Cell that conducts nerve impulses from one part of body to another part
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Neurons (nerve cells)
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3 Features of Neurons:
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1. High metabolic rate
2. Extreme longevity 3. nonmitotic |
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Three main structural regions of a neuron:
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cell body
dendrites axon |
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Neuron cell body
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o Contains typical organelles
o Nucleus, mitochondria, free ribosomes and rough ER (Nissl bodies) |
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Dendrites
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o Short processes from cell body
o receive nerve impulses o Carry to cell body |
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Axon
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o Single, long process from cell body
o Connects to cell body at axon hillock . o transmit nerve impulses to other cells |
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Structures Associated with Axons:
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1. Axon collaterals
2. Telodendria 3.Synaptic knobs |
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side branches of main axon
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Axon collaterals
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fine terminal extensions at the ends of axon and collaterals
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Telodendria
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expanded regions at tip of telodendria
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Synaptic knobs
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Structural Classification of Neurons
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Classified according to number of processes from cell body
Unipolar bipolar multipolar |
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single short process that branches like a T
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Unipolar neuron
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two processes, one dendrite and one axon
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Bipolar neuron
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many dendrites and a single axon
o most common of all neurons |
multipolar neuron
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Functional Classification of Neurons:
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1. Sensory (afferent) – sensory receptors to CNS
2. Motor (efferent) – impulses from CNS to muscles or glands 3. Interneurons– facilitate communication between sensory and motor neurons |
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Sometimes referred to as Neuroglia
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Glial cells
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Glial cell found..
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both CNS and PNS
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Glial cells are smaller than neurons and capable of...
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mitosis
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Physically protect and nourish neurons
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Glial cells
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These cells are more numerous than neurons...
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Glail cells
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_________more likely to be derived from glial cells than neurons
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Brain tumors
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Glial Cells of CNS
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Astrocytes
Ependymal Microglial Oligodenrocytes |
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Most abundant glial cells in CNS?
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Astrocytes
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Functions of Astrocytes
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Functions include:
1. Help to form the Blood-brain-barrier (BBB) 2. Regulate tissue fluid composition 3. Form a structural network 4. repair damaged neurons 5. Assist development of fetal neurons |
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Ependymal Cells
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Ciliated cuboidal epithelial cells
line ventricals of brain and central canal of spinal cord produce cerebral spinal fluid (CSF) and form the chrid plexus . |
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Small, motile cells(cleanup)
Wander through CNS exhibit Phagocytic activity remove cellular debris from dead or dying cells |
Microglial Cells
|
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Associated with CNS axons only
Wrap themselves around axons Produce myelin . Form myelin sheath . insulator of electrical activity |
Ogliodendrocytes
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Two types of glial cells in the PNS:
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Satellite Cells
Neurolemmocytes or Schwann Cells |
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Neurolemmocytes or Schwann Cells
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o Associated w/ PNS axons
o Same function as Ogliodendrocytes. Wrap around axons Produce myelin Form myelin sheath . |
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Satellite Cells
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o Flattened cells
o Found around cell bodies in ganglia Separate cell bodies Regulate exchange of nutrients and wastes. |
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Rapid conduction of electrical charge along plasma membrane
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Nerve Impulse or action potential
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Myelin consists mainly of
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Lipids
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Outer membrane of Myelin Sheath called
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Neurilemma
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Sheath forms when cell wraps around axon
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Cytoplasm and nucleus squeezed to periphery
Overlapping layers of membrane form sheath |
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can myelinate multiple axons
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Ogliodendrocyte
|
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can myelinate one axon
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Neurolemmacyte
|
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Gaps in the myelin sheath are called
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Neurofibril or Nodes of Ranvier
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The region that contains organelles such as the nucleus and Nissl bodies is the
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Cell Body
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Saltatory Conduction
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“jumping” from node to node
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Only place where action potential can occur
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Neurofibril or Nodes of Ranvier
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System that is more vulnerable to damage
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PNS
|
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Which is faster?
Myelinated or Unmyelinated Axon |
Myelinated
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3 factors involved in Axon repair:
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Amount of Damage.
– Secretion of growth factors by neurolemmocyte – distance between site of damaged axon and effector organ |
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Axon Regeneration:
Greater distance, (more of less) possibility of repair |
less
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Which System (CNS or PNS) has a greater chance of Axon Regeneration?
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PNS
|
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Why is Axon Regeneration limited in the CNS?
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Ogliodendrocytes do not secrete growth factor
• Actively inhibit growth |
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Nerve = bundle of
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Axons
|
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Nerve Structure:
Individual myelinated axon wrapped in___________ |
Endoneurium
|
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Nerve Structure:
Groups of axons bundled into_____ . • Surrounded by_____ |
Fascicles
Perineurium |
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Nerve Structure:
Fascicles bundled together by__________ |
Epineurium
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Junction between neuron and another neuron or an effector_____
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Synapse
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Nerve impulse transmitted to next cell by way of__________
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Synapse
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Synapse consists of:
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Presynaptic Neuron
Postsynaptic neuron Synaptic Cleft |
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Presynaptic Neuron
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Transmit impulse
|
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Postsynaptic neuron
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Receive impulse
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Synaptic Cleft
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Between Presynaptic Neuron and Postsynaptic neuron
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Three common types of Synapses:
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Axodendric
Axosomatic Axoanonic |
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Axodendric Synapse
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Presynaptic Axon to postsynaptic dendrite
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Synaptic Communication:
Sequence of events |
Impulse reaches Synaptic knob.
– Causes increase in ca++ in knob – Ca++ causes Synaptic vesicles to fuse w/membrane and release NT – NT bind receptors on postsyn. cell • Synaptic delay – time it takes NT to bind |
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Synaptic delay
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– time it takes Neurotransmitter to bind
|
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Neuronal Pools or Neuronal Pathways
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complex groupings of interneurons in CNS
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4 types of Neuronal Pools
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Converging circuit
Diverging circuit Reverberating Circuit Parallel-after-discharge |
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Converging circuit
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many neurons to one neuron
• Receives input from several neurons |
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Diverging circuit
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one neuron to many neurons
• One pool to multiple pools |
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Reverberating Circuit
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use feedback to produce repeated, cyclical stimulation of circuit
• Continues until inhibitory stimuli or synaptic fatigue |
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Parallel-after-discharge Circuit
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several neurons or pools process same info at one time
• Single presynaptic neuron stimulates different groups of neurons – Each neuron passes impulse to common postsynaptic cell Higher thought process |