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82 Cards in this Set

  • Front
  • Back
Two subdivisions of the Nervous System
Central nervous system (CNS)
Peripheral nervous system (PNS)
Central nervous system (CNS)
consists of
 brain and spinal cord
Peripheral nervous system (PNS) consists of
 cranial nerves, spinal nerves, and ganglia
CNS and PNS perform three general functions:
1. Collecting Information
2. Processing and evaluating information
3. Responding to information
Two functional divisions of the NS
Sensory NS
Motor NS
SNS Subdivided into two systems:
1. Somatic sensory – touch, pain, pressure, vibration and proprioception
2. Autonomic sensory – impulses from viscera
Motor Nervous
Somatic sensory
(Sensory NS)
touch, pain, pressure, vibration and proprioception
Visceral sensory
(Sensory NS)
impulses from viscera
Sensory NS(afferent)--sensory info from_____ receptors to_____ .
PNS, CNS
Motor NS(efferent)--sends impulses from _____ to _____ .
CNS, effectors
Somatic motor (voluntary)
(Motor NS)
causes contraction of skeletal muscles
Autonomic motor (involuntary)
(Motor NS)
regulates smooth and cardiac muscle and glands
Two distinct types of cells w/in NS:
Neurons
Glial cells
electrically excitable cells
o initiate, transmit and receive nerve impulses
Neurons
non-excitable cells
o support and protect neurons
Glial cells
Cell that is the structural and functional unit of NS
Neurons (nerve cells)
Cell that conducts nerve impulses from one part of body to another part
Neurons (nerve cells)
3 Features of Neurons:
1. High metabolic rate
2. Extreme longevity
3. nonmitotic
Three main structural regions of a neuron:
cell body
dendrites
axon
Neuron cell body
o Contains typical organelles
o Nucleus, mitochondria, free ribosomes and rough ER (Nissl bodies)
Dendrites
o Short processes from cell body
o receive nerve impulses
o Carry to cell body
Axon
o Single, long process from cell body
o Connects to cell body at axon hillock .
o transmit nerve impulses to other cells
Structures Associated with Axons:
1. Axon collaterals
2. Telodendria
3.Synaptic knobs
side branches of main axon
Axon collaterals
fine terminal extensions at the ends of axon and collaterals
Telodendria
expanded regions at tip of telodendria
Synaptic knobs
Structural Classification of Neurons
Classified according to number of processes from cell body
Unipolar
bipolar
multipolar
single short process that branches like a T
Unipolar neuron
two processes, one dendrite and one axon
Bipolar neuron
many dendrites and a single axon
o most common of all neurons
multipolar neuron
Functional Classification of Neurons:
1. Sensory (afferent) – sensory receptors to CNS
2. Motor (efferent) – impulses from CNS to muscles or glands
3. Interneurons– facilitate communication between sensory and motor neurons
Sometimes referred to as Neuroglia
Glial cells
Glial cell found..
both CNS and PNS
Glial cells are smaller than neurons and capable of...
mitosis
Physically protect and nourish neurons
Glial cells
These cells are more numerous than neurons...
Glail cells
_________more likely to be derived from glial cells than neurons
Brain tumors
Glial Cells of CNS
Astrocytes
Ependymal
Microglial
Oligodenrocytes
Most abundant glial cells in CNS?
Astrocytes
Functions of Astrocytes
Functions include:
1. Help to form the Blood-brain-barrier (BBB)
2. Regulate tissue fluid composition
3. Form a structural network
4. repair damaged neurons
5. Assist development of fetal neurons
Ependymal Cells
Ciliated cuboidal epithelial cells
 line ventricals of brain and central canal of spinal cord
 produce cerebral spinal fluid (CSF) and form the chrid plexus .
Small, motile cells(cleanup)
 Wander through CNS
 exhibit Phagocytic activity
 remove cellular debris from dead or dying cells
Microglial Cells
 Associated with CNS axons only
 Wrap themselves around axons
 Produce myelin .
 Form myelin sheath .
 insulator of electrical activity
Ogliodendrocytes
Two types of glial cells in the PNS:
Satellite Cells
Neurolemmocytes or Schwann Cells
Neurolemmocytes or Schwann Cells
o Associated w/ PNS axons
o Same function as Ogliodendrocytes.
 Wrap around axons Produce myelin
 Form myelin sheath .
Satellite Cells
o Flattened cells
o Found around cell bodies in ganglia
 Separate cell bodies
 Regulate exchange of nutrients and wastes.
Rapid conduction of electrical charge along plasma membrane
Nerve Impulse or action potential
Myelin consists mainly of
Lipids
Outer membrane of Myelin Sheath called
Neurilemma
Sheath forms when cell wraps around axon
Cytoplasm and nucleus squeezed to periphery
 Overlapping layers of membrane form sheath
can myelinate multiple axons
Ogliodendrocyte
can myelinate one axon
Neurolemmacyte
Gaps in the myelin sheath are called
Neurofibril or Nodes of Ranvier
The region that contains organelles such as the nucleus and Nissl bodies is the
Cell Body
Saltatory Conduction
“jumping” from node to node
Only place where action potential can occur
Neurofibril or Nodes of Ranvier
System that is more vulnerable to damage
PNS
Which is faster?
Myelinated or Unmyelinated Axon
Myelinated
3 factors involved in Axon repair:
Amount of Damage.
– Secretion of growth factors by neurolemmocyte
– distance between site of damaged axon and effector organ
Axon Regeneration:
Greater distance, (more of less) possibility of repair
less
Which System (CNS or PNS) has a greater chance of Axon Regeneration?
PNS
Why is Axon Regeneration limited in the CNS?
Ogliodendrocytes do not secrete growth factor
• Actively inhibit growth
Nerve = bundle of
Axons
Nerve Structure:
Individual myelinated axon wrapped in___________
Endoneurium
Nerve Structure:
Groups of axons bundled into_____ .
• Surrounded by_____
Fascicles
Perineurium
Nerve Structure:
Fascicles bundled together by__________
Epineurium
Junction between neuron and another neuron or an effector_____
Synapse
Nerve impulse transmitted to next cell by way of__________
Synapse
Synapse consists of:
Presynaptic Neuron
Postsynaptic neuron
Synaptic Cleft
Presynaptic Neuron
Transmit impulse
Postsynaptic neuron
Receive impulse
Synaptic Cleft
Between Presynaptic Neuron and Postsynaptic neuron
Three common types of Synapses:
Axodendric
Axosomatic
Axoanonic
Axodendric Synapse
Presynaptic Axon to postsynaptic dendrite
Synaptic Communication:
Sequence of events
Impulse reaches Synaptic knob.
– Causes increase in ca++ in knob
– Ca++ causes Synaptic vesicles to fuse w/membrane and release NT
– NT bind receptors on postsyn. cell
• Synaptic delay – time it takes NT to bind
Synaptic delay
– time it takes Neurotransmitter to bind
Neuronal Pools or Neuronal Pathways
complex groupings of interneurons in CNS
4 types of Neuronal Pools
Converging circuit
Diverging circuit
Reverberating Circuit
Parallel-after-discharge
Converging circuit
many neurons to one neuron
• Receives input from several neurons
Diverging circuit
one neuron to many neurons
• One pool to multiple pools
Reverberating Circuit
use feedback to produce repeated, cyclical stimulation of circuit
• Continues until inhibitory stimuli or synaptic fatigue
Parallel-after-discharge Circuit
several neurons or pools process same info at one time
• Single presynaptic neuron stimulates different groups of neurons
– Each neuron passes impulse to common postsynaptic cell
Higher thought process