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42 Cards in this Set
- Front
- Back
2 Structural Divisions
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CNS - brain and spinal cord
PNS - cranial nerves and spinal nerves |
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2 Functional Systems or Divisions
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Somatic NS - skeletal muscles
Autonomic NS - Smooth and cardiac muscles |
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2 arms of the autonomic
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sympathetic - F and F
parasympathetic - R and R |
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Afferent neurons
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Sensory - TO CNS
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Efferent neurons
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Motor - away from CNS
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Neurons
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The excitable, impulse transmitting cells which are the primary functional cells or units of the NS
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Astrocytes
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Blood brain barrier
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Microglia
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Immune cells
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ependymal
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epethelial cells, cerebrospinal fluid
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Oligodendrocytes
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myelinate
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Schwann cells
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in PNS, produce Myelin
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Satellite cells
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in PNS, structural support
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Input zone
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soma, dendrites
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Summation zone
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axon hillock
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conduction
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axon
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output zone
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telodendria and synaptic knobs
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Where are nerves found?
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in the PNS
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Where are tracts found?
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in the CNS
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epineurium
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surrounds entire nerve
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perineurium
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around fasicles of fibers
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endoneurium
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around each individual nerve fiber (axon)
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resting membrane potential
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-70mV
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charge inside of cells
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Negative
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charge outside of cells
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positive
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Why is the potassium-sodium pump important?
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transport Na OUT and K IN, to maintain polarity
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What is the nerve impulse called?
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Action potential
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Threshold potential
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-59 mV to -55mV
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What does the opening of Na+ channels produce?
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ion movement and changes in membrane potential.
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What happens when the threshold potential is reached?
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Voltage regulated Na channels are opened and the Action Potential Occurs. (going only one direction, down the axon away from the cell body) called DEPOLARIZATION
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Peak potential of the action potential
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+30mV
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What happens when the peak potential is reached?
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the Na+ channels are closed and the K+ channels are opened, so that K+ ions go OUT of the cells, so as to return the potential back to the -70mV resting level. Called REPOLARIZATION.
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2 types of conduction of the Action potential
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Continuous conduction - unmyelinated
and Saltatory conduction - myelinated, faster, jump |
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What is the synapse?
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The junction or connection, the site where nerve impulses are transmitted from neuron to the next neuron or to the effector
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What are the components of the synapse? (3)
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1. The synaptic bulb
2. a Synaptic cleft or space 3. plasma membrane of the Post synaptic cell |
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When does synaptic transmission occur?
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When the impulse reaches the synaptic bulb.
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Synaptic transmission step 1
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Action potential arrives
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synaptic transmission step 2
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voltage gated calcium channels open and Ca++ ions rush IN.
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synaptic transmission step 3
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Ca++ ions trigger the release of neurotransmitter (Ach, acetylcholine) from vesicles at te synaptic cleft
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synaptic transmission step 4
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Ach, diffuse across the cleft, and are bound to receptors at the post synaptic cell membrane
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synaptic transmission step 5
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in the post synaptic cell membrane, the neurotransmitter trigger opening of ion channels producing 'local' or gated potentials. These may be either excitatory or inhibitory, depending on the type of channels which are triggered
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synaptic transmission step 6
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neurotransmitter molecules are either removed and broken down, and recycled
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Acetylocholine
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the most common and most important of the neurotransmitters
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