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20 Cards in this Set

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Equation for CEREBRAL PERFUSION PRESSURE (CPP)
CPP = MAP -- ICP

Cerebral Perfusion Pressure = Mean Arterial Pressure ( - ) minus Intercranial Pressure
Cerebral Blood Flow requires what?
Oxygen and Glucose
Abnormal increases in ICP are associated with:
1. Altered production of CSF, circulation or absorption of CSF

2. Brain tumor, Injury, Edema, CVA

3. Icrease in cerebral blood
When there is an increase in ICP:
Perfusion of the brain is decreased or cut off.

No perfusion - no oxygen or glucose
Cause # 1 for increased ICP:

Tumor - Glioblastoma
Cause: Tumor

Mechanism: As the tumor grows it pushes on the brain --- decreases space for brain --- and increases ICP
Cause # 2 for increased ICP:

Hemorrhagic Stroke
Cause: Hemorrhagic Stroke (b/c of aneurysm)

Mechanism: A hemorrhagic stroke causes bleeding out in the brain -- the blood fills up intercranial space and there is less space available for the brain -- Increases pressure -- Increased ICP
Cause # 3 for increased ICP:

Hydrocephalus
Cause: Hydrocephalus

Mechanism: Overproduction of cerebral spinal fluid (CSF) -- causes a decrease in space for the brain -- increases pressure in the cranium -- Increased ICP
Type of CVA # 1:

Thrombotic Stroke
CVA type: Thrombotic Stroke

Mechanism: Atherosclerosis in cerebral artery -- collagen is exposed due to an injury to plaque -- primary and secondary hemostasis occurs -- clot forms which causes a blockage in the cerebral artery -- blockage causes a thrombotic stroke
Type of CVA # 2:

Embolitic Stroke
Embolitic Stroke CVA

Mechanism:

Atrial fibrillation in the heart -- stasis of blood in the atria -- thrombus is formed -- emboli breaks off and travels to the brain -- blocks cerebral artery -- decreases perfusion -- embolitic stroke
Type of CVA # 3:

Hemorrhagic Stroke
Hemorrhagic Stroke CVA

Mechanism: Aneurysm weakens a blood vessel in the brain -- HTN ruptures the aneurysm -- blood drains into cranial space -- there is decreased perfusion to the brain -- hemorrhagic stroke
Thrombotic or Embolytic stroke alternative mechanism:
Atherosclerosis -- stable plaque becomes unstable -- thrombus is formed (an embolus can break off) -- both a thrombus and an emboli will create a blockage -- decrease perfusion to the brain -- thrombotic or embolitic stroke
What causes a decrease in LOC?
Decreased perfusion to the brain will cause a decrease in LOC.
Clinical Manifestation of CVA # 1:

Decreased Motor Skills
Decreased Motor Skills:

Mechanism: Thrombosis (caused by atherosclerosis) within cerebral artery causes a blockage -- over time perfusion to the brain decreases -- as perfusion decreases ability to function also decreases -- one decrease in function is motor skills
Clinical Manifestation of CVA # 2:

Speech is affected
Speech is affected by a CVA because of decreased perfusion to the brain -- when the area of the brain that controls speech is not getting the perfusion it needs then it will have impact the ability of someone to speak
Clinical Manifestation of CVA # 3:

Thought processes affected
Decreased perfusion to the area of the brain that controls thought and higher thinking will affect a persons ability to think clearly.
Cerebral Cardial Accident:
Hemorrhage
Brain Shift
Usually occurs on the brain stem

Increases pressure on the brain stem
Reason why CVA is always an EMERGENCY:
CVA is always an emergency becauses it causes irreversible damage to the brain. The sooner a CVA is treated, the better because ischemic brain cells can be saved and the amount of brain damage done can be reduced.
Causes for decreased LOC:
CVA

Subdural Hematoma

Trauma
Clinical Manifestations of decreased LOC:
Inability to obey commands

Impaired speech

Thought processes impaired