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106 Cards in this Set

  • Front
  • Back

sensory

responding to stimuli; found in ganglion outside the CNS; bring info from outside to CNS

motor

motor nerve fibers; conducts impoulses from the CNS to effectors muscles and glands

integrative

Reasoning part of our brain


CNS takes information and relates it to each other, synthesize it and comes up with a response/conclusion

3 functions of the nervous system

1. sensory


2. integrative


3. motor

Where does most integrative processing happen?

CNS - cerebrum

CNS

Central Nervous System


-brain and spinal cord


-integrative and control centers

PNS

Peripheral Nervous System


-Sensory (afferent) division


-Motor (efferent) division

efferent system ______ the system

exits

ANS

Autonomic nervous system

sympathetic division

mobilizes body systems during activity (fight or flight)

autonomic nervous system ANS

-sympathetic division


-parasympathetic division

neurons

afferent (sensory) and efferent (motor) and interneuron (links within the CNS)

neurons

die when deprived of O2; little regeneration in CNS; slow regeneration in PNS; excitable/conduct

glial cells

protect and support neurons

glial cells

produce myelin; serve as a barrier in brain to toxins, pathogens, drugs (blood-brain barrier)

parts of the neuron

dendrite; cell body; axon; Schwann cells; axon terminals; synapses

dendrites

bring information TO the neuron; accepts/receives impulses

axon

transmits impulse FROM the dendrites; can be several feet long

Schwann cells

made of myelin; make transmission happen faster; does a hop skip down axon which makes it happen faster; contains impulses in axon so we can get it where we want it accurately

axon terminals

end of the signal; may go to another neuron/muscle cell

myelin sheath

like insulation on electrical wire; white matter; schwann cells/ speed up impulses; can be visible as muscle control (newborns, cerebral palsy)

When is the myelination process complete in people?

Teens - cognitive isn't quite complete until almost adulthood. (Think wiggly newborns.)

nerves

large bundle of axons wrapped in connective tissue (telephone cable). Emerge FROM (leave) spinal cord or base of brain and then branch

tracts

bundles of axons (nerves) IN the CNS. Ascending of descending. Cross over at the base of the brain

Cranial nerves

leave brain

spinal nerves

leave spinal cord through the vertebrae

ganglia

cell bodies grouped together outside CNS. Many are located just outside the spinal cord

white matter

myelinated nerve fibers

gray matter

mostly unmyleninated fibers and cell bodies

Myelinated makes the nerve fibers what "color"?

White - White Matter in the CNS.

Action Potential

way that we conduct an electrical signal along the cell to pass it to the other cell it's trying to send info to

resting potential

There are fewer positive ions inside neuron than in tissue fluid. Positive ions inside the cell are potassium (K+), whereas positive ions outside the cell are sodium (Na+). As long as inside is negative and outside is positive, neuron is polarized and will stay inactive.

Which ions are outside of the cell?

Na+ (sodium)

Which ions are inside of the cell?

K+ (potassium)

Depolarization phase

In response to a stimulus, the cell membrane becomes permeable to sodium ions, so they rapidly enter the cell through sodium channels in the membrane. Continued Na+ diffusion causes depolarization of the cell.

Repolarization phase

The membrane then becomes impermeable to sodium and permeable to K+. K+ diffuses out of the cell to repolarize the membrane.

Action Potential Phases

-Depolarization phase


-Repolarization phase


-After-Hyperpolarization phase


-Refractory Period

After-Hyperpolarization Phase

Prolonged outflow of potassium ions causes the potential difference across the membrane to decrease more than resting state.


After K gates close, the Na-K pump and leakage channels restore to resting concentrations of sodium and potassium allowing membrane to return to a resting state

Refractory Period

Following onset of an action potential, there is a period during which a neuron cannot generate further action potentials in response to normal threshold stimuli.


This prevents backwards depolarization and keeps the electrical impulse moving toward the axon terminal.

Conduction of Action Potential

-Threshold stimulus - minimum stimulus needed to start AP


-AP propagates another at an adjacent point and continues along entire length of neuron


-AP jumps from node to node in myelin sheath

Sodium influx creates a local region of ______

positive charge on the inside of the axon membrane with respect to the outside

Potential difference results in _______

local flow of current, in the form of ions, between these regions

Conduction between neurons

At the synapse, a neurotransmitter (ex: ecatylcholine) diffuses across synaptic cleft and reacts with receptors

ecatylcholine

neurotransmitter

Things that impact conduction

-alcohol, sedatives, anesthetics, cold, continuous pressure slow or stop conduction


-caffeine lowers the threshold of synapses

EEG (electroencephalogram)

Way you can measure the amount of electricity going on in your nervous system. Measuring Action Potentials.


Represent total electrical activity of neruons in the brain, as a recorded by electrodes places on the forehead and scalp.


A recording of brain waves.

Brain waves

Amalgamation of the many APs generated by the neurons in the brain.

Reflexes

-type of conduction pathway


-important tool for evaluation of NS


-automatic, unconscious response to changes occurring inside or outside the body


-simplest ex of a neural response


-bypasses the brain, quick


-attempts to keep the body in balance

5 components of a reflex arc

1. receptor


2. sensory neuron


3. center


4. motor neuron


5. effector

Types of reflexes

autonomic


somatic

autonomic reflex

regulates smooth muscles


ex: salivary reflex, papillary reflex, hearts, glands

somatic reflex

stimulates skeletal muscles; sometimes conscious inhibition or facilitation


ex: bladder

Most common reflex site for an adult and why routine?

Patellar (knee) reflex


b/c checking on the CNS, this nerve, reflex depression/suppression

moro reflex

used with infants via startling them/just observing when not bundled watching for spread of arms/grabbing of fingers

babinski reflex

one of the foot reflex tests for infants; tested by running stimulus along the side and toes stretch

CNS consists of __________

brain and spinal cord

3 major regions of the brain

1. Cerebrum (latest developed, most complex)


2. Cerebellum


3. Dienchephalon


4. Brain stem (most primitive)



(As you go outward on the brain - you get more developed/complex.)

limbic system

connection between emotion and reasoning

cerebrum

largest part of brain, most superior, most recent via evolution; 2 hemispheres totally separate except for corpus collusum



-interprets sensation


-control motor acts


-intellect


-reason


-memory


-consciousness, language, personality

Diencphalon

-thalamus


-hypothalamus


-epithalamus


-choroid plexu

thalamus

relay station for sensory impulese passing upward toward brain. crude recognition of pleasant or not


everything passes through on way to cerebrum

hypothalamus

-link between mind/body/nervous/endocrine


-regulates temperature, appetite, sex, vitals, homeostatis

epithalamus

pineal body; biological clock (bear hibernation)

choroid plexus

form cerebrospinal fluid; exist in four different areas

brain stem

all nerve tracts between spinal cord and brain pass here. Fibers cross so right brain controls left body.


Vital reflex center. (things that keep us alive are controlled here)


very deep in brain - best protected

6 funcitons of brain stem

1. respiratory center


2. heart rate control


3. swallowing, vomiting, BP control


4. transmit impulses from cerebrum to cerebellum


5. visual and auditory reflexes


6. consciousness and wake/sleep cycles RAS (Reticular activating system)

coma

RAS inactivity

RAS

Reticular Formation


-motor control of visceral organs


-responsible for consciousness (wake/sleep)


-network that rouses the cerebral cortex


-screens incoming sensory info so cerebrum is not constantly bombarded (habituation)


- sleep results from decreased activity of RAS


-active cerebrum can stimulate the RF to cause sleeplessness

cerebellum

-cauliflower-looking-section in back of brain


-fine coordination of muscle movement


-helps to maintain muscle tone


-balance


-Compares brain's intentions with actual body performance and makes corrections

hemisphere dominance

-"left brained" "right brained"


-90% of people are L hemisphere dominant for language activities, complex intellectual functions requiring verbal, analytical, computational skills.


-Non-dominant side specializes in non-verbal functions like motor, visual, musical, emotional, intuitive.

circadian rhythm

24 cycle of sleep and wakefulness

wakefulness

state of consciousness; ability to react to stimuli


sleep

state of partial unconsciousness; less able to respond to stimuli

2 different types of sleep

NREM (non rapid eye movement sleep)


REM (rapid eye movement sleep)

Limbic System

-encircles the top of brain stem (hypothalamus, medial parts of cerebral cortex)


-plays role in emotions, subconscious drives, sex, biological rhythm, motivation, pain, pleasure


-evolved early, instinctive behavior similar to animal responses that relate to survival but in humans are modified by the cerebral cortex

cerebral cortex

outer layer or cerebrum

short term memory

stored weakly and for a limited period of time

long term memory

required consolidation - attention, repetition, associative ideas

meninges

3 layers of membrane that cover the entire CNS

3 meninges

1. dura mater (outer)


2. arachnoid


3. pia mater (inner most)

meningitis

inflammation of meninges caused by bacteria or virus


-may spread to nervous tissue (DANGER)


-diagnosed by taking a sample of cerebrospinal fluid from subarachnoid space

cerebral spinal fluid

-produces in ventricles of dienchephalon of brain


-protects against mechanical injury


-dissolves and transports substances


-hydrates


-4 ventricles filled with fluid

Normal volume of cerebral spinal fluid

3-5 oz

Too much cerebral spinal fluid results in

pressure in the brain and in a fetus you can grow a big head b/c bones are not fused

CSF

cerebrospinal fluid

blood brain barrier

capillaries in brain have extra-tight junctures/walls so they become impassible for larger molecules of many drugs and chemicals (except for certain psychotropic drugs - alcohol, LSD, mental health meds)

cerebrovascular accident

stroke; circulation to brain area is blocked as in blood clot or ruptured blood vessel; vital brain tissue dies

After a stroke, how are certain abilities regained/relearned

undamaged neurons spread to areas where neurons have died

spinal cord

two way conduction between brain and PNS; simple reflex actions

How many of the vertebra are considered the spinal cord?

first 2/3rds of vertebra

Why are epidurals given below the 3rd lumbar vertebrae?

Don't want to hit spinal cord

dorsal root

sensory neurons


damage = loss of sensation

ventral root

motor neurons


damage = paralysis

spinal nerves

-dorsal root


-ventral root

3 types of nerves

1. sensory nerves


2. motor


3. autonomic

nerves

bundle of fibers found outside the CNS

sensory nerves

mechanoreceptor - touch, pressure, vibration, streth


-thermoreceptor - temp


-photoreceptor - light


-chemoreceptor - chemicals


-nociceptor - chemical released at site of tissue damage


-osmoreceptor - osmotic pressure

sensory adaptation

receptors adapt, impulses are triggered only if strength of stimulation is changed; pain adapts very little (smells/noises at home "fade")

How many cranial nerves are there?

12 (roman numerals)


innervate the eyes, face, tongue, throat, visceral organs.

How many spinal nerves are there?

31


(C1-8, T1-12, L1-5, S1-5, Coccyx-1)

2 arms of autonomic NS

1. sympathetic


2. parasympathetic

sympathetic

dominates in stress; excitory system (pupils dilate, pulse increases, decreased bowel activity, blood vessels dilate, increased adrenalin)

parasympathetic

active in periods of rest; maintains/restores energy (pupils constrict, decreased pulse, increased bowel activity, sexual organs stimulated)

Nerves found in the uterus come from what region of the spinal nerves?

sacral region

referred pain

visceral pain is sometimes referred to a region with a common nerve pathway


(ex - heart attack in women can feel it in their face; pelvic organs refer pain to the upper back/scapula; in labor pain in hips and legs)

What is the theory behind referred pain

nerves that travel near each other may cause "jumping sensation"