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63 Cards in this Set
- Front
- Back
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what cancer is associated with down's syndrome
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ALL and AML
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what cancer is associated with xeroderma pigmentosum
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melanoma, BCC and especially SCC of the skin
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what cancer is associated with chronic atrophic gastritis, pernicious anemia and postsurgical gastric remnants
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gastric adenocarcinoma
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tuberoius sclerosis (facial angiofibroma, seizures and mental retardation)
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PG: rhabdomyoma
astrocytoma and angiomyolipoma |
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actinic keratosis
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SCC of the skin
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barret's esophagus
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esophageal adenocarcinoma
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plummer vinson syndrome
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SCC of the esophagus
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cirrhosis (alcoholic, HepB or HepC)
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hepatocellular carcinoma
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ulcerative colitis > Crohn's
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colonic carcinoma
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paget's disease of the bone
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secondary osteosarcoma and fibrosarcoma
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what cancer is associated with Auto immune diseases
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lymphoma
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what cancer is associated with acanthosis nigricans
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visceral malignancy (including stomach, lung, breast and uterus)
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what cancer is associated with dysplastic nevus
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malignant melanoma
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what cancer is associated with radiation exposure
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myeloid leukemia ( AML and CML) and papillary thyroid cancer
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what cancer is associated with the gain of function mutation of the oncogene abl
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CML (tyrosine kinase)
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what cancer is associated with the gain of function mutation of the oncogene c-myc
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burkitt's lymphoma (transcription factor)
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what cancer is associated with the gain of function mutation of the oncogene Bcl-2
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follicular and undifferentiated lymphomas (inhibits apoptosis)
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what cancer is associated with the gain of function mutation of the oncogene erb-2
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Breat, ovarian and gastric carcinomas (tyrosine kinase)
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what cancer is associated with the gain of function mutation of the oncogene RAS
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colon carcinoma (GTPase)
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what cancer is associated with the gain of function mutation of the oncogene L-myc
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lung tumor (transcription factor)
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what cancer is associated with the gain of function mutation of the oncogene N-myc
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adrenal neuroblastoma
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what cancer is associated with the gain of function mutation of the oncogene RET
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multiple endocrine neoplasia (MEN) types IIa and IIb
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what cancer is associated with the gain of function mutation of the oncogene c-kit
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gastrointestinal stromal tumor
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Rb
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retinoblastoma and osteosarcoma
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p53
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most human cancers; Li Fraumani syndrome
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BRCA1
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breast and ovarian cancer
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BRCA2
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breast cancer
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p16
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melanoma
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APC
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colorectal cancer
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WT1
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wilms tumor
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NF1
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neurofibromatosis 1
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NF2
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neurofibromatosis 2
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DPC
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pancreatic cancer (deleted in Panco cancer)
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DCC
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colon cancer (deleted in colon cancer)
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CA-125 tumor marker
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ovarian and malignant epithelial tumors
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s-100 tumor marker
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melanoma, neural tumors and astrocytomas
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alkaline phosphatase tumor marker
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mets to bone, obstructive biliary disease and paget's disease of the bone
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bobesin tumor marker
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adrenal neuroblastoma, lung and gastric cancer
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TRAP tumor marker
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hairy cell leukemia
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CA19-9 tumor marker
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pancreatic cancer
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calcitonin as a tumor marker
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thyroid medullary carcinoma
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HTLV-1 is an oncogenic microbe for
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adult t-cell leukemia/lymphoma
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HBV and HCV are oncogenic microbes for
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hepatocellular carcinoma
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EBV is an oncogenic microbe for
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burkitt's lymphoma, HL and nasopharyngeal CA
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HPV is an oncogenic microbe for
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cervical, penile and anal CA (16,18,31,33)
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hhv-8 is an oncogenic microbe for
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kaposi's sarcoma (AIDs pts)
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HIV is an oncogenic microbe for
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primary CNS lymphoma
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H. pylori is an oncogenic microbe for
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gastric adenocarcinoma
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schistosoma haematobium is an oncogenic microbe for
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SCC of transitional epithelium fo the bladder
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aflatoxin is a chemical carcinogen associated with...
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hepatocellular carcinoma
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vinyl chloride is a chemical carcinogen associated with...
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angiosarcoma
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CCL4 is a chemical carcinogen associated with...
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centrolobular necrosis and fattty change of the liver
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nitrosamines from smoked foods are chemicals carcinogen associated with...
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gastric cancer
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cigarette smoke is a chemical carcinogen associated with...
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SCC of the larnx and lung, SCLC, RCC and transitional cell carcinoma of the bladder
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asbestos is a chemical carcinogen associated with...
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Bronchogenic CA > mesothelioma
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arsenic is a chemical carcinogen associated with...
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SCC and angiosarcoma
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naphtalene (aniline) dyes is a chemical carcinogen associated with...
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transitional cell carcinoma of the baldder
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alkylating agents are chemical carcinogens associated with
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leukemia
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4 cancers with psammoma bodies
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papillary adenocarcinoma of the thyroid, serous papillary cystadenocarcinoma of the ovary, meningioma and malignant mesothelioma
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top 3 incidence of cancer in men
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prostate > lung > colon
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top 4 cancer killers of men
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lung > prostate > colon > panco
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top 3 incedince of cancer in women
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breast >lung > colon
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top 4 killers of cancer in women
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Lung > breast >colon > panco
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