Neoplasia I

Front 1

What is the derivation of neoplasia?

Back 1

From the Greek, meaning new growth.

Front 2

What is neoplasia?

Back 2

A pathologic process characterized by loss of the normal control mechanisms that regulate cell growth, morphogenesis, and differentiation

Front 3

Which pathologic process is defined as the permanent loss or alteration of cellular growth controls, resulting in continuous proliferation?

Back 3

Neoplasia.

Front 4

Is neoplasia a reversible or irreversible process?

Back 4

irreversible

Front 5

Which word means pertaining to neoplasia?

Back 5

Neoplastic.

Front 6

A collection of neoplastic tissue is referred to as a n_______.

Back 6

neoplasm

Front 7

Neoplasms are commonly referred to as t_______.

Back 7

tumors

Front 8

While often used as a synonym for neoplasm, the word _______ can also be used to indicate any swelling.

Back 8

tumors

Front 9

Which word is commonly used to refer to any malignant neoplasm?

Back 9

Cancer.

Front 10

Regarding neoplasia, the word cancer is used to indicate any neoplasm that is _______.

Back 10

malignant

Front 11

Define metastasis.

Back 11

The spread of a disease from one part of the body to another

Front 12

Intermediate neoplasms are sometimes referred to as b_______ tumors because they appear to straddle the dividing line between benign and malignant neoplasms.

Back 12

borderline

Front 13

In general, how are benign neoplasms treated?

Back 13

By excision.

Front 14

If the cells in a tumor look like the normal adult cells in the tissue of origin, the tumor is said to be well _______.

Back 14

differentiated

Front 15

If the cells in a tumor do not look like the normal adult cells in the tissue of origin, the tumor is said to be _______ differentiated.

Back 15

poorly

Front 16

The cells of a benign neoplasm tend to be _______ (well/poorly) differentiated.

Back 16

well

Front 17

Define anaplasia.

Back 17

The replacement of specialized cells with unspecialized or undifferentiated cells.

Front 18

A neoplastic cell that does not resemble normal tissue at all is said to be a_______.

Back 18

anaplastic

Front 19

What is aneuploidy?

Back 19

Having a number of chromosomes that is not an exact multiple of the haploid number. In humans, this describes any cell with a chromosomal number that is not a multiple of 23.

Front 20

Is aneuploidy more characteristic of benign or malignant tumors?

Back 20

Malignant.

Front 21

What is a totipotent cell?

Back 21

A cell that has the potential to become any type of cell in the adult body or any cell of the extraembryonic membranes. Mnemonic: Total Potential.

Front 22

What is a pluripotent cell?

Back 22

A cell that has the potential to become any type of cell in the adult body but does not have the ability to become a cell of the extraembryonic membranes. Mnemonic: Plural is more than one, but not all.

Front 23

What are permanent cells?

Back 23

Nondividing cells with no regenerative ability.

Front 24

Of pluripotent cells, totipotent cells, differentiated cells, and permanent cells, which can differentiate into any cell type?

Back 24

Totipotent cells.

Front 25

Of pluripotent cells, totipotent cells, differentiated cells, and permanent cells, which can differentiate into several cell types but not every cell type?

Back 25

Pluripotent cells.

Front 26

Of pluripotent cells, totipotent cells, differentiated cells, and permanent cells, which cannot differentiate and divide?

Back 26

Permanent cells.

Front 27

Of pluripotent cells, totipotent cells, differentiated cells, and permanent cells, which can only differentiate into one or several very closely related cell types?

Back 27

Differentiated cells.

Front 28

Of pluripotent cells, totipotent cells, differentiated cells, and permanent cells, which do not give rise to neoplasms?

Back 28

Permanent cells.

Front 29

Of pluripotent cells, totipotent cells, differentiated cells, and permanent cells, which give rise to most human tumors?

Back 29

Differentiated cells.

Front 30

In a person (as opposed to an embryo), which is the only class of totipotent cells?

Back 30

Germ cells.

Front 31

What is the derivation of neoplasia?

Back 31

From the Greek, meaning new growth.

Front 32

What is neoplasia?

Back 32

A pathologic process characterized by loss of the normal control mechanisms that regulate cell growth, morphogenesis, and differentiation

Front 33

Which pathologic process is defined as the permanent loss or alteration of cellular growth controls, resulting in continuous proliferation?

Back 33

Neoplasia.

Front 34

Is neoplasia a reversible or irreversible process?

Back 34

irreversible

Front 35

Which word means pertaining to neoplasia?

Back 35

Neoplastic.

Front 36

A collection of neoplastic tissue is referred to as a n_______.

Back 36

neoplasm

Front 37

Neoplasms are commonly referred to as t_______.

Back 37

tumors

Front 38

While often used as a synonym for neoplasm, the word _______ can also be used to indicate any swelling.

Back 38

tumors

Front 39

Which word is commonly used to refer to any malignant neoplasm?

Back 39

Cancer.

Front 40

Regarding neoplasia, the word cancer is used to indicate any neoplasm that is _______.

Back 40

malignant

Front 41

Define metastasis.

Back 41

The spread of a disease from one part of the body to another

Front 42

Intermediate neoplasms are sometimes referred to as b_______ tumors because they appear to straddle the dividing line between benign and malignant neoplasms.

Back 42

borderline

Front 43

In general, how are benign neoplasms treated?

Back 43

By excision.

Front 44

If the cells in a tumor look like the normal adult cells in the tissue of origin, the tumor is said to be well _______.

Back 44

differentiated

Front 45

If the cells in a tumor do not look like the normal adult cells in the tissue of origin, the tumor is said to be _______ differentiated.

Back 45

poorly