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45 Cards in this Set

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What is the derivation of neoplasia?
From the Greek, meaning new growth.
What is neoplasia?
A pathologic process characterized by loss of the normal control mechanisms that regulate cell growth, morphogenesis, and differentiation
Which pathologic process is defined as the permanent loss or alteration of cellular growth controls, resulting in continuous proliferation?
Neoplasia.
Is neoplasia a reversible or irreversible process?
irreversible
Which word means pertaining to neoplasia?
Neoplastic.
A collection of neoplastic tissue is referred to as a n_______.
neoplasm
Neoplasms are commonly referred to as t_______.
tumors
While often used as a synonym for neoplasm, the word _______ can also be used to indicate any swelling.
tumors
Which word is commonly used to refer to any malignant neoplasm?
Cancer.
Regarding neoplasia, the word cancer is used to indicate any neoplasm that is _______.
malignant
Define metastasis.
The spread of a disease from one part of the body to another
Intermediate neoplasms are sometimes referred to as b_______ tumors because they appear to straddle the dividing line between benign and malignant neoplasms.
borderline
In general, how are benign neoplasms treated?
By excision.
If the cells in a tumor look like the normal adult cells in the tissue of origin, the tumor is said to be well _______.
differentiated
If the cells in a tumor do not look like the normal adult cells in the tissue of origin, the tumor is said to be _______ differentiated.
poorly
The cells of a benign neoplasm tend to be _______ (well/poorly) differentiated.
well
Define anaplasia.
The replacement of specialized cells with unspecialized or undifferentiated cells.
A neoplastic cell that does not resemble normal tissue at all is said to be a_______.
anaplastic
What is aneuploidy?
Having a number of chromosomes that is not an exact multiple of the haploid number. In humans, this describes any cell with a chromosomal number that is not a multiple of 23.
Is aneuploidy more characteristic of benign or malignant tumors?
Malignant.
What is a totipotent cell?
A cell that has the potential to become any type of cell in the adult body or any cell of the extraembryonic membranes. Mnemonic: Total Potential.
What is a pluripotent cell?
A cell that has the potential to become any type of cell in the adult body but does not have the ability to become a cell of the extraembryonic membranes. Mnemonic: Plural is more than one, but not all.
What are permanent cells?
Nondividing cells with no regenerative ability.
Of pluripotent cells, totipotent cells, differentiated cells, and permanent cells, which can differentiate into any cell type?
Totipotent cells.
Of pluripotent cells, totipotent cells, differentiated cells, and permanent cells, which can differentiate into several cell types but not every cell type?
Pluripotent cells.
Of pluripotent cells, totipotent cells, differentiated cells, and permanent cells, which cannot differentiate and divide?
Permanent cells.
Of pluripotent cells, totipotent cells, differentiated cells, and permanent cells, which can only differentiate into one or several very closely related cell types?
Differentiated cells.
Of pluripotent cells, totipotent cells, differentiated cells, and permanent cells, which do not give rise to neoplasms?
Permanent cells.
Of pluripotent cells, totipotent cells, differentiated cells, and permanent cells, which give rise to most human tumors?
Differentiated cells.
In a person (as opposed to an embryo), which is the only class of totipotent cells?
Germ cells.
What is the derivation of neoplasia?
From the Greek, meaning new growth.
What is neoplasia?
A pathologic process characterized by loss of the normal control mechanisms that regulate cell growth, morphogenesis, and differentiation
Which pathologic process is defined as the permanent loss or alteration of cellular growth controls, resulting in continuous proliferation?
Neoplasia.
Is neoplasia a reversible or irreversible process?
irreversible
Which word means pertaining to neoplasia?
Neoplastic.
A collection of neoplastic tissue is referred to as a n_______.
neoplasm
Neoplasms are commonly referred to as t_______.
tumors
While often used as a synonym for neoplasm, the word _______ can also be used to indicate any swelling.
tumors
Which word is commonly used to refer to any malignant neoplasm?
Cancer.
Regarding neoplasia, the word cancer is used to indicate any neoplasm that is _______.
malignant
Define metastasis.
The spread of a disease from one part of the body to another
Intermediate neoplasms are sometimes referred to as b_______ tumors because they appear to straddle the dividing line between benign and malignant neoplasms.
borderline
In general, how are benign neoplasms treated?
By excision.
If the cells in a tumor look like the normal adult cells in the tissue of origin, the tumor is said to be well _______.
differentiated
If the cells in a tumor do not look like the normal adult cells in the tissue of origin, the tumor is said to be _______ differentiated.
poorly