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20 Cards in this Set

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T/F: Pediatric renal function approximates adult renal function at 1-2 years of age?

True

What is apnea of prematurity related to?

Underdeveloped brainstem


Compare length of treatment differences between a <28 week gestation vs >28 week gestation.

<28 weeks: treat until 43 weeks postmenstrual age


>28 weeks: 37 weeks PMA

What should supplemental oxygen saturations for AOP be between?

85%-95%

What is a nonpharmacologic treatment to increase oxygen carry capacity?

Red blood cells transfusion

What is the pharmacologic therapy for AOP?

Methylxanthines

What is the MOA of methylxanthines?

Inhibits adenosine and Inhibits phosphodiesterase

Define BPD

Chronic lung disease of infancy in which the infant lung is characterized by inflammation and fibrosis

Bronchopulmonary dysplasia

Define RDS

Lung condition of prematurity. A respiratory disorder caused by surfactant deficiency.

Respiratory Distress Syndrome

Define atelectasis

Complete or partial collapse of the lung

Due to inadequate surfactant production

What are the critical components of surfactant required for normal respiratory function?

Phosphatidylcholine, surfactant protein B, surfactant protein C

Definitive diagnosis of PDA?

Echocardiogram with left to right flow

What is patent ductus aeteriosus?

Ductus aeteriosus remaining open after birth

Untreated PDA?

CHF congestive heart failure


Hypoperfusion of brain, intestines, kidneys

Refractory hypotension may be due to?

PDA

When is alprostadil .05 mcg/kg/min continuous infusion used?

Maintenance of PDA

How do you manage CHF related to PDA?

Fluid restriction


Diuretics

Betamethasone 12 mg IM daily x2 doses for what?

Antenatal steroidnfor prevention of PDA

How is AOP recognized?



Cessation of breathing for at least 20 seconds or a briefer episode with one of the following...


Bradycardia (low HR)


Cyanosis (bluish coloration)


Pallor (pale appearance)

Apnea of Prematurity

What other causes must first be ruled out before the diagnosis of AOP?

CNS disorders


Decreased oxygen delivery to brain


Infection


Metabolic disorders


Thermal instability