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14 Cards in this Set

  • Front
  • Back
most common cause of brain malformations
abnormal neuronal migration
how do physical lesions (ex. hemorrhage) interfere w/ migration
by disrupting radial glia fibers
Porencephaly anatomic defect
cavity that communicates from subarachnoid space to ventricular system
the term porencephaly is used to describe what radiological finding
big hole in cerebral hemisphere
_ is porencephaly w/ complete division of 1 hemisphere
Schizencephaly
Schizencephaly cause
stroke that cause to not develop -> gray matter present from surface to ventricle
presentation of Schizencephaly
seizures
sometimes normal development
strokes that happen later have better prognosis
lissencephaly refers to
smooth brain - absence of sulci, gyri and normal cortical architectuer
when does a fetus develop sulci and gyri
mid 20th wks
lissencephaly brain has how many layers
4 instead of 6
outcome of lissencephaly
seizures
not much else
pachgyra anatomical abnormality
thick gryi
no sulci
architectural abnormality in that cortex is generally thickened and the alignment of neurons is deranged
cortical heterotopia anatomic abnormality
gray matter in wrong area
SX of cortical heterotopia
seizures