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22 Cards in this Set
- Front
- Back
What are the three categories of nematodes?
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1) intestinal 2) extraintestinal 3) tissue
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What is an example of a tissue nematode?
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Trichinella spiralis
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What are 4 examples of intestinal nematodes?
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1) Ascaris lumbricoides 2) Enterobius vermicularis 3) Strongyloides sterocoralis 4) Hookworm
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What is the largest roundworm that parasitizes the human intestine?
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Ascaris lumbricoides
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What is the most common helminthic infection worldwide?
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Ascaris lumbricoides
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What is Loeffler's sydrome?
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A pneumonitis with a marked eosinophilia caused by a worm infection
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Describe the lifecycle of ascaris
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The eggs are ingested and hatch in the intestines, migrate into the intestinal lymphatics and move to the lungs
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What are symptoms of ascaris infection?
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Abdominal pain and intestinal obstruction; also pulmonary symptoms of cough, dyspnea, hemoptysis and Loeffler's syndrome when the lung phase of larval migration occurs
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What is the most common clinical manifestation of enterobius vermicularis?
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perianal pruritus, especially at night, and abdominal pain
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Describe the lifecycle of enterobius vermicularis
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The eggs are ingested from contaminated fingers and make their way to the cecum; the adults live in the cecum and migrate to the anus at night and lay eggs, with self-inoculation following due to prutitus
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Describe the test used to demonstrate the eggs of enterobius vermicularis
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The "scotch tape" test is used which involves using transparent tape to probe the perianal region and then looking at the tape under a microscope for eggs
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What phase of the life cycle of strongyloides sterocoralis is infective and which is diagnostic?
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The infective stage is the filariform larval stage and the rhabditiform stage is diagnostic
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How does strongyloides get into the body?
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It penetrates the skin
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Describe how strongyloides reaches the intestine
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The filariform larvae invades the skin and gets into the bloodstream, spreading to the lungs where it infects the alveolar spaces. It is carried to the trachea and swallowed into the stomach and passes into the intestine
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Describe the eosinophilia in strongyloides infections and in what patients do they disseminate?
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Eosinophilia is present during the acute and chronic stages but is absent in disseminated infections (which occur in immunocompromised patients)
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What is clinical manifestation is often seen with hookworm infection and why does it occur?
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Iron deficiency anemia often occurs because the worm attaches to the intestine leading to bleeding
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How does a hookworm infestation occur?
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The filariform larvae enter the skin and migrate to the intestine
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How does the trichinellosis infection occur?
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The ingestion of undercooked or raw beef or pork
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Where are the larvae in a trichinella infection?
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The larvae are found in the muscle
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What are common symptoms of trichinellosis?
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periorbital and facial edema, conjuctivitis, myalgias and weakness, blood eosinophilia
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What is usually found in the muscle of patients with trichinellosis?
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Larval encystment
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What is the preferred diagnostic test used to confirm trichinellosis?
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Muscle biopsy
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