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9 Cards in this Set
- Front
- Back
- 3rd side (hint)
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What are the two main components of D50?
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D50 is 50% dextrose in water
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One may also encounter varying concentrations of dextrose (e.g. D5W is 5% dextrose in water) and different solvents (e.g. D5NS is 5% dextrose in normal saline).
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What is the functional class of D50?
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Carbohydrate
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Dextrose is so named because it consists of the dextrorotatory isomers of glucose
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What is the mechanism of action of D50?
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Principal form of glucose used by the body to create energy
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Glycolysis, the metabolism of glucose, is found in nearly all known organisms.
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What are the listed indications for D50?
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Hypoglycemia
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D50 is used with insulin for in-hospital treatment of hyperkalemia
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What are the listed contraindications for D50?
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None in a patient with documented hypoglycemia
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Some people may claim to have an allergy to glucose/dextrose. As the body produces glucose, this is impossible.
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What are the listed precautions for D50?
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Use with caution in patients with increasing ICP as the added glucose may worsen the cerebral edema. Consider blood glucose monitoring before and after administration. Monitor for localized venous irritation
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Wernicke's encephalopathy may be exacerbated if D50 is administered without thiamine.
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What are the listed side effects for D50?
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- Tissue necrosis
- Phlebitis - Pain at injection site |
D50's side effects result from its hypertonicity
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What are the listed interactions for D50?
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None
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Hyperglycemia from D50 may interfere with the use of fludeoxyglucose f 18 (Gludef, Metatrace) in PET scans.
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What is the dosage and route of D50?
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Adult:
- 25g of a 50% solution IVP PRN Pediatric - 0.5g/kg IVP or IO using a 25% solution - If under 10kg, use 10% solution |
D50 can be administered IO but is reported to be exceptionally painful due to the viscosity.
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