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127 Cards in this Set

  • Front
  • Back
botulinum toxin
ACh Release Inhibitor, Snap25, Cosmetic and Spasm
vancomycin
Active only against gram+ bacteria, Inhibits the enzyme, peptidoglycan synthetase, responsible for adding the dissacharide, RED MAN
Esmolol
Adernergic “Selective” B1-blockers, ( 8 min) short half life, emrgencies
Atenolol
Adernergic “Selective” B1-blockers
Clonidine
Adernergic A-2 agonist, chemical sympthectome
Methyldopa
Adernergic A-2 agonist, methyldopa safe in pregnancy, some autoimmune response, chemical sympthectome
Dopamine
Adernergic agonist - [low] B1>B2, [high] all
Dobutamine
Adernergic agonist - [low] B1>B2, [high] all *Selective for contractility without affecting rate
Epinephrine
Adernergic agonist - [low] Betas, [high] all
Phenoxybenzamine
Adernergic Alpha(1>2) blockers (irreversible)
Phenylephrine
Adernergic Alpha1 Agonist. decongestant, pupilary dilator
Norepinephrine
Adernergic Alpha1 and Beta1 Agonist
Terbutaline
Adernergic B2 Selective agonist. Athsma
Albuterol
Adernergic Beta 2 Agonist
Isoproterenol
Adernergic Beta only Agonist
Cocaine (Mechanism Only)
Adernergic Blocks NET
Imipramine (Mechanism Only)
Adernergic Blocks NET
Atomoxetine (Mechanism Only)
Adernergic Blocks NET
Reserpine (Mechanism Only)
Adernergic Blocks VMAT(into vessical transporter) Cause depleation of NE Presynaptic
Ephedrine
Adernergic CNS stimulant (weak A and B agonist, and also a releaser of NE). nasal decongestant and a pressor
Methylphenidate
Adernergic CNS Stimulant for ADHD
Amphetamine
Adernergic displacement of NE (FED) ->sympathomimetic effects
Guanethidine (Mechanism Only)
Adernergic Displaces NE in Vessicles, reducing availabel concentration, enters via NET, Historic Anti-HTN
Tyramine (Mechanism Only)
Adernergic Metabolixed by Monoamine oxidase, On MAOI, it displaces the NE and NE Exits vis FED --> Hypertensive
Phentolamine
Adernergic Non-selective alpha blocker
Propanolol
Adernergic Non-selective Beta Blocker
Timolol
Adernergic non-selective beta blocker, glaucoma
Prazosin
Adernergic Selective alpha-1 blocker (reversible)
Conivaptan
ADH Antagonist, CD-V1a and V2 ADH Receptors
Streptomycin
Aminoglycosides,
Gentamicin
Aminoglycosides,
Amikacin
Aminoglycosides,
Neomycin
Aminoglycosides, poorly absorbed from gut (used as bowel sterilant)
Question
Answer
Nifedipine
Anti-Anginal, Dihydropyradine, Ca++ Blocker
Nimodipine
Anti-Anginal, Dihydropyradine, Ca++ Blocker
Verapamil
Anti-Anginal, Non-Dihydropyradine, Ca++ Blocker
Diltiazem
Anti-Anginal, Non-Dihydropyradine, Ca++ Blocker
Nitroglycerin
Anti-Anginal, Organic Nitrate
Isosorbide dinitrate
Anti-Anginal, Organic Nitrate
amlodipine
Anti-Hypertensive, Dihydropyridine Calcium Channel Blockers - Reflex Tachy
captopril
Anti-Hypertensive, (ACE) Inhibitors
propranolol
Anti-Hypertensive, All Beta blocker
losartan
Anti-Hypertensive, Angiotension Receptor Blockers
hydrochlorothiazide
Anti-Hypertensive, Diuretic -distal convoluted tubule - inhibit Na-Cl co-transport
methyldopa
Anti-Hypertensive, Inhibitors of Central adrenergic function- depletes norepinephrine, SAFE IN PREG
guanethidine
Anti-Hypertensive, Inhibitors of peripheral adrenergic function- depletes norepinephrine
reserpine
Anti-Hypertensive, Inhibitors of peripheral adrenergic function- depletes norepinephrine
amiloride
Anti-Hypertensive, K-sparing diuretics
verapamil
Anti-Hypertensive, Non-dihydropyridine calcium channel blockers
clonidine
Anti-Hypertensive, α2 agonist
prazosin
Anti-Hypertensive, α-blockers, “first does phenomenon”
imipenem-cilastatin
Carbapenemases, imipenem to prevent breakdown, Seizures
meropenem
carbapenems
Acetazolamide
Carbonic Anhydrase Inhibitor, PT and CD
penicillin G
Cell Wall Inhibitor
amoxicillin
Cell Wall Inhibitor, Extended Spectrum, Better GI Absorb
ampicillin
Cell Wall Inhibitor, Extended Spectrum, GI Probs
piperacillin
Cell Wall Inhibitor, Extended Spectrum, Only given IV or IM
bacitracin
Cell wall inhibitor, inhibits recycling of the lipid carrier
cycloserine
Cell wall inhibitor, inhibits the racemase and synthetase, 2nd line TB
nafcillin
Cell Wall Inhibitor, IV use mainly
cefazolin
Cephalosporin, 1st Gen,
cephalexin
Cephalosporin, 1st Gen,
cefoxitin
Cephalosporin, 2nd Gen, IV,
ceftriaxone
Cephalosporin, 3rd Gen, Crosses BBB
ceftazidime
Cephalosporin, 3rd Gen, Crosses BBB
pralidoxime
Cholinesterase Reactivator
amoxicillin + clavulanic acid
Clavulanic acid- inhibitor of bacterial beta lactamase, Improves activity
daptomycin
Cyclic lipopeptide, Forms ion conducting pore, Needs Calcium
clindamycin
Derivative of lincomycin L in MLS, Pseudomembranous colitis
acetylcholine
Direct-Acting Cholenergic Agonist
bethanechol
Direct-Acting Cholenergic Agonist
Metabolized by
acetylcholinesterase? No
Muscarinic
Cholenergic? Any Dose
Nicotinic
Cholenergic? NO
nicotine
Direct-Acting Cholenergic Agonists
varenicline
Direct-Acting Cholenergic Agonists
carbachol
Direct-Acting Cholenergics, Metabolized by
acetylcholinesterase? NO
Muscarinic
Cholenergic? Any Dose
Nicotinic
Cholenergic? High Dose
Treatment of Glaucoma
Ciprofloxacin
Fluoroquinolones
Diphenhydramine
H1 Antagonist 1st Gen (Benadryl®) Motion and Sleep
Chlorpheniramine
H1 Antagonist 1st Gen (Chlortrimeton®), OTC Cold Meds
Dimenhydrinate
H1 Antagonist 1st Gen (Dramamine®) Motion
Loratadine
H1 Antagonist 2nd Gen (Claritin®)
Fexofenadine
H1 Antagonist 2nd Gen (Allegra®)
Cetirizine
H1 Antagonist 2nd Gen (Zyrtec ®)
Cimetidine
H2 Antagonists (Tagamet®), Hormonal Effects(gynomastia, Impotence), Big CYP interactions
Ranitidine
H2 Antagonists (Zantac®)
Famotidine
H2 Antagonists (Pepcid®)
donepezil
Indirect-Acting Cholenergic Agonists, Anticholenesterase, Alzheimers
rivastigmine
Indirect-Acting Cholenergic Agonists, Anticholenesterase, Alzheimers
galantamine
Indirect-Acting Cholenergic Agonists, Anticholenesterase, Alzheimers
sarin
Indirect-Acting Cholenergic Agonists, Anticholenesterase, Death
physostigmine
Indirect-Acting Cholenergic Agonists, Anticholenesterase, Glaucoma
edrophonium
Indirect-Acting Cholenergic Agonists, Anticholenesterase, Myestinia Gravis Diag, Illius
neostigmine
Indirect-Acting Cholenergic Agonists, Anticholenesterase, Myestinia Gravis, Illius
telithromycin
Ketolide, 50% by CYP 3A4,
Furoseminde
Loop Diuretic, Na/K/2Cl (Acending loop)
erythromycin
Macrolide antibiotic
azithromycin
Macrolide antibiotic, Azithromycin penetrates tissues well (CNS exception), T1/2=3Days, Does not inhibit cytochrome P-450
clarithromycin
Macrolide antibiotic, More stable to acid than erythromycin
Cromolyn Sodium
Mast Cell Stabilizer (Nasalcrom®)
Spirolactone
Mineralcorticode antagonist, Aldosterone Antagonist (Competetive), CD, K+ Sparing
Eplerenone
Mineralcorticode antagonist, Aldosterone Antagonist (Competetive), CD, K+ Sparing
aztreonam
Monobactam
atropine
Muscarinic Antagonists, Crosses BBB, Used Pre Surgery
ipratropium
Muscarinic Antagonists, Used for COPD
Amiloride
Na+ Channel Blocker, K+ Sparing, CD
hexamethonium
Nicotinic Antagonists, Disected aorta, a3b2
vecuronium
Nicotinic Antagonists, Paralysis
tubocurarine
Nicotinic Antagonists, Paralysis, Hypotension(mast Cells)
succinylcholine
Nicotinic Antagonists, Quick Paralysis, faculations first, metabolized by ACHase-don’t use neo
Mannitol
Osmotic Diuretic, PT-Decending Loop-CD
linezolid
Oxazolidinone class, inhibitor of monoamine oxidase - avaoid tyrosine,
H1 Antagonist Side Effects
Sedation, CNS Effects, Non specific hit other receptors (anti-ach)
Cotrimazole
Sulfonamide
Dapsone
Sulfonamide, treatment of leprosy (w/rifampin)
Sulfisoxazole
Sulfonamide, urinary tract infections
Sulfamethoxazole
Sulfonamide, urinary tract infections (combo w/ trimethoprim)
Tetracycline
Tetracyclines,
Doxycycline
Tetracyclines,
Minocycline
Tetracyclines,
Tigecycline
Tetracyclines, IV only
Hydrochlorothiazide
Thiazide Diuretic, Na/Cl Cotransporter (DCT)
Chloramphenicol
topical usage for bacterial conjunctivitis - interfere with eukaryotic, mitochondrial ribosomes BAD, Gray Baby Syndrome
Methenamine
Urinary Antiseptic Agent, low pH (<5.5) to yield formaldehyde
Nitrofurantoin
Urinary Antiseptic Agent, reduction in bacteria (not humans)
metronidazole
With nitroreductase forms radicals. anaerobic infections and for pseudomembranous colitis due to C. difficile. Anabuse like, Inhibit P450. Brown Pee
Caffeine
Xanthine Blocks Phostdiesterase metabolism of cAMP, Andenosine Antagonist
Theophylline
Xanthine Relaxes Bronchi