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7 Cards in this Set

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"caine" suffix=

local anesthetic i.e. lidoCAINE

"coxib" suffix =

cyclooxygenase (COX)-2 inhibitors




ie celeCOXIB




COX-2 plays a major role in prostaglandin biosynthesis in inflammatory cells and in the CNS. Prostaglandin synthesis is a key factor in the development of inflammation and hyperalgesia.


COX-2 inhibitors have analgesic and anti-inflammatory activity by blocking the transformation of arachidonic acid into prostaglandin H2 selectively.

"dipine" suffix =

CCB


ie nifeDIPINE




disrupt the movement of calcium (Ca2+) through calcium channels.


Calcium channel blockers are used as antihypertensive drugs.


CCBs are particularly effective against large vessel stiffness, one of the common causes of elevated systolic blood pressure

"dronate" suffix =

biphosphonate


ie alenDRONATE






prevent the loss of bone mass, used to treat osteoporosis

"fungin" suffix =

gluten synthesis inhibitor, antifungal




ie caspoFUNGIN

"gliptin" suffix =

dipeptidyl peptidase-4 inhibitor drug for type 2 diabetes


ie. sitaGLIPTIN

"pril" suffix =

angiotension-converting enzyme (ACE) inhibitors


ie CaptoPRIL